SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cii'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3cii NATURAL KILLER CELLS
ANTIGEN CD94
(Homo
sapiens) 		4 / 6 TYR G 115
ILE G 173
SER G 110
SER G 111
 None
 1.21A 3pmzD-3ciiG:
undetectable		 3pmzD-3ciiG:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3cii NATURAL KILLER CELLS
ANTIGEN CD94
(Homo
sapiens) 		5 / 12 PHE G 114
GLU G 104
LEU G 119
ILE G 153
LEU G 162
 None
 1.37A 4k38B-3ciiG:
undetectable		 4k38B-3ciiG:
16.80