SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 221
LEU A 224
VAL A 225
SER A 227
LEU A 138
 None
 1.10A 1db1A-3cijA:
undetectable		 1db1A-3cijA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 10 LEU A 160
ALA A 162
ILE A 163
ALA A 118
LEU A 230
 None
 1.02A 1xp0A-3cijA:
undetectable		 1xp0A-3cijA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		4 / 5 ASP A 152
MET A 213
LEU A 230
HIS A 223
 None
 1.12A 2jfaA-3cijA:
undetectable		 2jfaA-3cijA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 315
LEU A 318
GLY A 319
GLN A 242
LEU A 323
 None
 1.16A 2oz7A-3cijA:
undetectable		 2oz7A-3cijA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		4 / 5 ASP A 152
MET A 213
LEU A 230
HIS A 223
 None
 1.14A 2qxsA-3cijA:
undetectable		 2qxsA-3cijA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		4 / 5 ASP A 152
MET A 213
LEU A 230
HIS A 223
 None
 1.15A 2qxsB-3cijA:
undetectable		 2qxsB-3cijA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 11 HIS A  58
ALA A  53
GLU A 310
VAL A  63
VAL A  86
 None
 1.05A 2uxpB-3cijA:
undetectable		 2uxpB-3cijA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 9 PRO A  46
LEU A 315
LEU A  43
ALA A  88
PHE A 110
 None
 1.18A 2vcvD-3cijA:
undetectable		 2vcvD-3cijA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 9 PRO A  46
LEU A 315
LEU A  43
ALA A  88
PHE A 110
 None
 1.18A 2vcvE-3cijA:
undetectable		 2vcvE-3cijA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 9 PRO A  46
LEU A 315
LEU A  43
ALA A  88
PHE A 110
 None
 1.18A 2vcvH-3cijA:
undetectable		 2vcvH-3cijA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 9 PRO A  46
LEU A 315
LEU A  43
ALA A  88
PHE A 110
 None
 1.23A 2vcvI-3cijA:
undetectable		 2vcvI-3cijA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 287
PHE A 110
GLN A 312
LEU A 315
THR A 107
 None
 1.31A 2w3mB-3cijA:
undetectable		 2w3mB-3cijA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 12 PRO A 150
GLY A 156
ASN A 151
ILE A  74
THR A  78
 None
 0.98A 4n49A-3cijA:
undetectable		 4n49A-3cijA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 10 TYR A 157
LEU A  94
LEU A  43
ALA A  40
GLY A 286
 None
None
None
WO4  A 400 (-3.3A)
None
 1.27A 4rn6A-3cijA:
undetectable		 4rn6A-3cijA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		3 / 3 ASN A 149
SER A 202
ARG A  75
 None
 0.78A 5b2qA-3cijA:
undetectable		 5b2qA-3cijA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 12 LEU A  94
ALA A  90
PHE A 147
VAL A 268
PHE A 188
 None
WO4  A 400 (-3.5A)
None
None
None
 1.32A 5x6yA-3cijA:
2.5		 5x6yA-3cijA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 12 GLU A  66
THR A  44
GLU A  45
HIS A 243
HIS A 223
 None
 1.33A 5xioB-3cijA:
2.1		 5xioB-3cijA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 3cij UPF0100 PROTEIN
AF_0094
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 205
SER A 184
LEU A 272
ASN A 151
ILE A 212
 None
 1.34A 6dwnB-3cijA:
undetectable		 6dwnB-3cijA:
14.51