SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cim'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2I_C_QPSC1060_1 (ALPHA-1,4-GLUCAN LYASE ISOZYME 1)	3cim	CARBON DIOXIDE-CONCENTRATIN G MECHANISM PROTEIN CCMK HOMOLOG 2 (Synechocystis sp.)	5 / 12	THR A 10 VAL A 44 VAL A 67 GLY A 70 ALA A 64	None	1.01A	2x2iC-3cimA: undetectable	2x2iC-3cimA: 7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA152_0 (ILEAL BILE ACID-BINDING PROTEIN)	3cim	CARBON DIOXIDE-CONCENTRATIN G MECHANISM PROTEIN CCMK HOMOLOG 2 (Synechocystis sp.)	3 / 3	VAL A 5 LYS A 3 HIS A 96	None	0.83A	3elzA-3cimA: undetectable	3elzA-3cimA: 21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FPJ_A_SAMA301_0 (PUTATIVE UNCHARACTERIZED PROTEIN)	3cim	CARBON DIOXIDE-CONCENTRATIN G MECHANISM PROTEIN CCMK HOMOLOG 2 (Synechocystis sp.)	5 / 12	ILE A 61 GLY A 60 VAL A 57 ALA A 63 VAL A 72	None	0.95A	3fpjA-3cimA: undetectable	3fpjA-3cimA: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K50_C_ACTC1403_0 (L-THREONINE 3-DEHYDROGENASE)	3cim	CARBON DIOXIDE-CONCENTRATIN G MECHANISM PROTEIN CCMK HOMOLOG 2 (Synechocystis sp.)	4 / 4	MET A 23 SER A 56 VAL A 53 GLY A 6	None	1.22A	5k50C-3cimA: 0.0	5k50C-3cimA: 15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YSI_A_NCAA1001_0 (UBIQUITINATING/DEUBI QUITINATING ENZYME SDEA)	3cim	CARBON DIOXIDE-CONCENTRATIN G MECHANISM PROTEIN CCMK HOMOLOG 2 (Synechocystis sp.)	4 / 6	ARG A 11 GLY A 40 THR A 10 VAL A 42	GOL A 101 (-3.0A) None None None	1.11A	5ysiA-3cimA: undetectable	5ysiA-3cimA: 18.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X2I_C_QPSC1060_1","ALPHA-1,4-GLUCAN LYASE ISOZYME 1","3cim","CARBON DIOXIDE-CONCENTRATING MECHANISM PROTEIN CCMK HOMOLOG 2","Synechocystis sp.",5,"THR A  10;VAL A  44;VAL A  67;GLY A  70;ALA A  64","None","1.01A","2x2iC-3cimA:undetectable","2x2iC-3cimA:7.46"],["3ELZ_A_CHDA152_0","ILEAL BILE ACID-BINDING PROTEIN","3cim","CARBON DIOXIDE-CONCENTRATING MECHANISM PROTEIN CCMK HOMOLOG 2","Synechocystis sp.",3,"VAL A   5;LYS A   3;HIS A  96","None","0.83A","3elzA-3cimA:undetectable","3elzA-3cimA:21.99"],["3FPJ_A_SAMA301_0","PUTATIVE UNCHARACTERIZED PROTEIN","3cim","CARBON DIOXIDE-CONCENTRATING MECHANISM PROTEIN CCMK HOMOLOG 2","Synechocystis sp.",5,"ILE A  61;GLY A  60;VAL A  57;ALA A  63;VAL A  72","None","0.95A","3fpjA-3cimA:undetectable","3fpjA-3cimA:19.80"],["5K50_C_ACTC1403_0","L-THREONINE 3-DEHYDROGENASE","3cim","CARBON DIOXIDE-CONCENTRATING MECHANISM PROTEIN CCMK HOMOLOG 2","Synechocystis sp.",4,"MET A  23;SER A  56;VAL A  53;GLY A   6","None","1.22A","5k50C-3cimA:0.0","5k50C-3cimA:15.62"],["5YSI_A_NCAA1001_0","UBIQUITINATING\/DEUBIQUITINATING ENZYME SDEA","3cim","CARBON DIOXIDE-CONCENTRATING MECHANISM PROTEIN CCMK HOMOLOG 2","Synechocystis sp.",4,"ARG A  11;GLY A  40;THR A  10;VAL A  42","GOL A 101 (-3.0A);None;None;None","1.11A","5ysiA-3cimA:undetectable","5ysiA-3cimA:18.35"]]