SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cj1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 9 THR A 172
LEU A 176
VAL A  69
GLY A  70
VAL A  43
 None
 1.43A 1dz8A-3cj1A:
undetectable		 1dz8A-3cj1A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 4 THR A 136
LEU A 140
VAL A 143
LEU A 147
 None
 0.63A 1fbmB-3cj1A:
undetectable		 1fbmB-3cj1A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 4 THR A 136
LEU A 140
VAL A 143
LEU A 147
 None
 0.46A 1fbmD-3cj1A:
undetectable		 1fbmD-3cj1A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 5 THR A 136
LEU A 140
VAL A 143
LEU A 147
 None
 0.56A 1fbmE-3cj1A:
undetectable		 1fbmE-3cj1A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 7 GLY A  81
HIS A  50
THR A 122
ILE A  82
 None
 0.94A 1gtnF-3cj1A:
undetectable
1gtnG-3cj1A:
undetectable		 1gtnF-3cj1A:
10.64
1gtnG-3cj1A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 7 GLY A  81
HIS A  50
THR A 122
ILE A  82
 None
 0.98A 1gtnJ-3cj1A:
undetectable
1gtnK-3cj1A:
undetectable		 1gtnJ-3cj1A:
10.64
1gtnK-3cj1A:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 4 THR A 136
LEU A 140
VAL A 143
LEU A 147
 None
 0.76A 1mz9D-3cj1A:
undetectable		 1mz9D-3cj1A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A  47
ALA A  46
ASP A  45
VAL A 139
ILE A  82
 None
 1.12A 1sduB-3cj1A:
undetectable		 1sduB-3cj1A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 11 GLU A  63
ILE A 448
LEU A 442
TYR A 229
ILE A 181
 None
 0.96A 2dg9A-3cj1A:
undetectable		 2dg9A-3cj1A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A  47
ALA A  46
ASP A  45
VAL A 139
ILE A  82
 None
 1.02A 2f81A-3cj1A:
undetectable		 2f81A-3cj1A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_0
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 THR A 351
TYR A 350
GLY A 204
GLY A 124
HIS A  50
 None
 0.95A 2fk8A-3cj1A:
undetectable		 2fk8A-3cj1A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A  47
ALA A  46
ASP A  45
VAL A 139
ILE A  82
 None
 1.05A 2hs2B-3cj1A:
undetectable		 2hs2B-3cj1A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 4 SER A  48
GLY A 124
GLY A 203
GLY A 244
 None
 0.92A 3bogB-3cj1A:
undetectable
3bogD-3cj1A:
undetectable		 3bogB-3cj1A:
undetectable
3bogD-3cj1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 VAL A 167
GLY A 166
SER A 161
ALA A 199
THR A 210
 None
 1.23A 3dh0A-3cj1A:
undetectable		 3dh0A-3cj1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 8 ILE A 448
TYR A 233
HIS A 232
GLY A 230
 None
 0.92A 3em0B-3cj1A:
undetectable		 3em0B-3cj1A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A 244
LEU A 250
SER A  49
GLY A  47
SER A  48
 None
 1.05A 3g2oA-3cj1A:
undetectable		 3g2oA-3cj1A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 ALA A 205
GLY A 244
SER A  49
GLY A  47
SER A  48
 None
 1.08A 3g2oB-3cj1A:
undetectable		 3g2oB-3cj1A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A 244
LEU A 250
SER A  49
GLY A  47
SER A  48
 None
 1.01A 3g2oB-3cj1A:
undetectable		 3g2oB-3cj1A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 6 HIS A 225
ARG A 234
PHE A 334
PRO A 336
 None
 1.32A 3gclA-3cj1A:
undetectable		 3gclA-3cj1A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 7 LEU A 140
ARG A 126
SER A  95
GLY A  47
 None
 1.04A 3hcrB-3cj1A:
2.4		 3hcrB-3cj1A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A 204
ASP A 246
ILE A 248
ASP A 201
LEU A 202
 None
 1.10A 3iv6B-3cj1A:
undetectable		 3iv6B-3cj1A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLU A 165
GLY A 166
GLY A 203
SER A 206
PHE A 240
 None
 1.01A 3k13C-3cj1A:
undetectable		 3k13C-3cj1A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 4 GLY A 120
ASP A  45
GLY A 439
THR A 445
 None
 1.10A 3k4vC-3cj1A:
undetectable		 3k4vC-3cj1A:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA201_1
(PROTEIN S100-A4)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 9 GLY A 203
ILE A 209
PHE A 420
PHE A 348
PHE A 425
 None
 1.43A 3ko0A-3cj1A:
0.8
3ko0C-3cj1A:
0.7		 3ko0A-3cj1A:
11.67
3ko0C-3cj1A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 8 GLY A 203
ILE A 209
PHE A 420
PHE A 348
PHE A 425
 None
 1.43A 3ko0B-3cj1A:
0.7
3ko0J-3cj1A:
undetectable		 3ko0B-3cj1A:
11.67
3ko0J-3cj1A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC201_1
(PROTEIN S100-A4)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 9 PHE A 348
PHE A 425
GLY A 203
ILE A 209
PHE A 420
 None
 1.37A 3ko0A-3cj1A:
0.8
3ko0C-3cj1A:
0.7		 3ko0A-3cj1A:
11.67
3ko0C-3cj1A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN201_1
(PROTEIN S100-A4)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 10 PHE A 348
PHE A 425
GLY A 203
ILE A 209
PHE A 420
 None
 1.41A 3ko0L-3cj1A:
0.8
3ko0N-3cj1A:
0.7		 3ko0L-3cj1A:
11.67
3ko0N-3cj1A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 10 GLY A 203
ILE A 209
PHE A 420
PHE A 348
PHE A 425
 None
 1.44A 3ko0R-3cj1A:
undetectable
3ko0T-3cj1A:
0.8		 3ko0R-3cj1A:
11.67
3ko0T-3cj1A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 11 HIS A 238
PHE A 404
GLY A 203
GLY A 204
GLU A 165
 None
 1.10A 4fglA-3cj1A:
undetectable
4fglB-3cj1A:
undetectable		 4fglA-3cj1A:
16.99
4fglB-3cj1A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A  81
GLY A  80
GLY A  79
ALA A  46
VAL A 143
 None
 0.91A 4htfA-3cj1A:
undetectable		 4htfA-3cj1A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A  81
GLY A  80
GLY A  79
ALA A  46
VAL A 143
 None
 0.90A 4htfB-3cj1A:
undetectable		 4htfB-3cj1A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 ALA A 123
GLY A 124
SER A  83
ASN A 129
GLY A 162
 None
 0.96A 4obwA-3cj1A:
undetectable		 4obwA-3cj1A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA601_1
(SERUM ALBUMIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 11 ASN A 443
PHE A 168
VAL A 171
GLY A 439
LEU A 228
 None
 1.24A 4or0A-3cj1A:
undetectable		 4or0A-3cj1A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 ASN A 443
PHE A 168
VAL A 171
GLY A 439
LEU A 228
 None
 1.34A 4ot2A-3cj1A:
undetectable		 4ot2A-3cj1A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLY A 204
ALA A 205
SER A 206
TYR A 349
ASP A 201
 None
 1.16A 4rtpA-3cj1A:
undetectable		 4rtpA-3cj1A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		3 / 3 ALA A 437
TYR A 440
PRO A 116
 None
 0.69A 4zdyA-3cj1A:
undetectable		 4zdyA-3cj1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 GLN A 288
LEU A 317
LEU A 313
ILE A 259
ALA A 256
 None
 1.41A 5xprA-3cj1A:
undetectable		 5xprA-3cj1A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		4 / 4 LEU A 202
ASP A 201
GLN A 208
VAL A 279
 None
 1.43A 6bzoF-3cj1A:
undetectable		 6bzoF-3cj1A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 12 ASN A 443
PHE A 168
VAL A 171
GLY A 439
LEU A 228
 None
 1.33A 6ci6A-3cj1A:
undetectable		 6ci6A-3cj1A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 10 LEU A 100
THR A  51
VAL A 143
VAL A  77
LEU A 147
 None
 1.14A 6czmA-3cj1A:
undetectable
6czmC-3cj1A:
undetectable		 6czmA-3cj1A:
24.63
6czmC-3cj1A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 9 VAL A 143
VAL A  77
LEU A 147
LEU A 100
THR A  51
 None
 1.08A 6czmA-3cj1A:
undetectable
6czmB-3cj1A:
undetectable		 6czmA-3cj1A:
24.63
6czmB-3cj1A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 9 VAL A 143
VAL A  77
LEU A 147
LEU A 100
THR A  51
 None
 1.12A 6czmB-3cj1A:
undetectable
6czmC-3cj1A:
undetectable		 6czmB-3cj1A:
24.63
6czmC-3cj1A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 9 VAL A 143
VAL A  77
LEU A 147
LEU A 100
THR A  51
 None
 1.09A 6czmD-3cj1A:
undetectable
6czmE-3cj1A:
undetectable		 6czmD-3cj1A:
24.63
6czmE-3cj1A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2
(Rattus
norvegicus) 		5 / 10 VAL A 143
VAL A  77
LEU A 147
LEU A 100
THR A  51
 None
 1.09A 6czmE-3cj1A:
undetectable
6czmF-3cj1A:
undetectable		 6czmE-3cj1A:
24.63
6czmF-3cj1A:
24.63