SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cjd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		5 / 12 ARG A  13
GLY A  64
GLU A  21
VAL A  62
GLU A  14
 None
 1.31A 1jdvE-3cjdA:
undetectable
1jdvF-3cjdA:
undetectable		 1jdvE-3cjdA:
21.63
1jdvF-3cjdA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		4 / 5 LEU A 107
ARG A  65
ARG A  69
ILE A  17
 CL  A 202 (-4.1A)
None
None
None
 1.28A 2cmlA-3cjdA:
undetectable		 2cmlA-3cjdA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		4 / 5 LEU A 107
ARG A  65
ARG A  69
ILE A  17
 CL  A 202 (-4.1A)
None
None
None
 1.27A 2cmlB-3cjdA:
undetectable		 2cmlB-3cjdA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		4 / 5 LEU A 107
ARG A  65
ARG A  69
ILE A  17
 CL  A 202 (-4.1A)
None
None
None
 1.27A 2cmlC-3cjdA:
undetectable		 2cmlC-3cjdA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		4 / 5 LEU A 107
ARG A  65
ARG A  69
ILE A  17
 CL  A 202 (-4.1A)
None
None
None
 1.28A 2cmlD-3cjdA:
undetectable		 2cmlD-3cjdA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		4 / 6 LEU A  19
GLN A  23
GLU A  25
ILE A  24
 None
 1.07A 2fcnA-3cjdA:
undetectable
2fcnB-3cjdA:
undetectable		 2fcnA-3cjdA:
20.20
2fcnB-3cjdA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		5 / 11 LEU A  32
ALA A 110
GLY A  64
ALA A  20
ILE A  24
 None
 0.91A 2idwA-3cjdA:
undetectable		 2idwA-3cjdA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		5 / 10 ALA A  34
LEU A  58
LEU A  55
HIS A  51
LEU A  16
 None
 1.21A 3erdB-3cjdA:
undetectable		 3erdB-3cjdA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		3 / 3 ARG A  65
ARG A  69
ILE A  17
 None
 0.87A 4b7qC-3cjdA:
undetectable		 4b7qC-3cjdA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		5 / 12 GLU A  25
LEU A 107
ARG A  65
ARG A  69
ILE A  17
 None
CL  A 202 (-4.1A)
None
None
None
 1.25A 4mwvA-3cjdA:
undetectable		 4mwvA-3cjdA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		5 / 11 ALA A  34
LEU A  58
LEU A  55
HIS A  51
LEU A  16
 None
 1.18A 4zn7B-3cjdA:
undetectable		 4zn7B-3cjdA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		5 / 12 ALA A 129
HIS A 128
LEU A 133
ALA A 131
PHE A 134
 None
None
STE  A 203 (-4.0A)
None
None
 1.11A 5k9dA-3cjdA:
undetectable		 5k9dA-3cjdA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3cjd TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Jannaschia
sp.
CCS1) 		4 / 8 VAL A 164
HIS A  95
GLY A 171
LEU A 172
 None
 0.80A 5w3jB-3cjdA:
undetectable		 5w3jB-3cjdA:
18.18