SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3cje OSMC-LIKE PROTEIN
(Jannaschia
sp.
CCS1) 		4 / 4 ILE A  66
LEU A  69
VAL A  73
ALA A 136
 None
 0.93A 1mz9A-3cjeA:
undetectable		 1mz9A-3cjeA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3cje OSMC-LIKE PROTEIN
(Jannaschia
sp.
CCS1) 		4 / 5 ILE A  66
LEU A  69
VAL A  73
ALA A 136
 None
 0.87A 1mz9C-3cjeA:
undetectable		 1mz9C-3cjeA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 3cje OSMC-LIKE PROTEIN
(Jannaschia
sp.
CCS1) 		5 / 9 VAL A  73
THR A  70
ASP A 118
ILE A 119
VAL A  93
 None
 1.40A 2l8mA-3cjeA:
undetectable		 2l8mA-3cjeA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 3cje OSMC-LIKE PROTEIN
(Jannaschia
sp.
CCS1) 		4 / 5 LEU A  69
GLN A  76
LEU A 143
GLU A 144
 None
 1.02A 3h5gA-3cjeA:
undetectable
3h5gB-3cjeA:
undetectable		 3h5gA-3cjeA:
12.35
3h5gB-3cjeA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3cje OSMC-LIKE PROTEIN
(Jannaschia
sp.
CCS1) 		4 / 8 LEU A  44
LEU A  30
VAL A  32
ILE A  66
 None
 0.87A 4oj4A-3cjeA:
undetectable		 4oj4A-3cjeA:
21.35