SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cji'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)
3cji POLYPROTEIN
POLYPROTEIN

(Senecavirus
A;
Senecavirus
A)
4 / 6 TRP C 187
THR A  80
LEU A 106
GLY A  90
None
1.33A 1gtiC-3cjiC:
undetectable
1gtiC-3cjiC:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 169
ILE A 217
TRP A 140
None
1.08A 1m8eB-3cjiA:
undetectable
1m8eB-3cjiA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 169
ILE A 217
TRP A 140
None
1.12A 1nodB-3cjiA:
undetectable
1nodB-3cjiA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 6 GLY C  94
VAL C  83
ALA C  88
SER C  91
None
1.00A 1p6kA-3cjiC:
undetectable
1p6kA-3cjiC:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 169
ILE A 217
TRP A 140
None
1.16A 1qomA-3cjiA:
undetectable
1qomA-3cjiA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 TRP C 236
THR A 117
TYR A 118
None
1.21A 2a3aA-3cjiC:
undetectable
2a3aA-3cjiC:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 TRP C 236
THR A 117
TYR A 118
None
1.23A 2a3bA-3cjiC:
undetectable
2a3bA-3cjiC:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 8 GLY C 279
PHE C 109
THR C 232
SER A 202
None
1.03A 2a8tB-3cjiC:
undetectable
2a8tB-3cjiC:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)
3cji POLYPROTEIN
POLYPROTEIN
POLYPROTEIN

(Senecavirus
A;
Senecavirus
A;
Senecavirus
A)
3 / 3 ASP B  21
ASP A 122
ASN D  16
None
0.80A 2bm9D-3cjiB:
undetectable
2bm9D-3cjiB:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 12 THR C 139
VAL C 119
ALA C  82
PHE C  80
VAL C 133
None
1.30A 2g72A-3cjiC:
undetectable
2g72A-3cjiC:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 7 THR C 225
SER C  48
SER C  49
LEU A 201
None
0.93A 2hdnE-3cjiC:
undetectable
2hdnF-3cjiC:
undetectable
2hdnH-3cjiC:
undetectable
2hdnE-3cjiC:
9.26
2hdnF-3cjiC:
19.44
2hdnH-3cjiC:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 7 SER C  49
LEU A 201
THR C 225
SER C  48
None
0.95A 2hdnF-3cjiC:
undetectable
2hdnG-3cjiC:
undetectable
2hdnH-3cjiC:
undetectable
2hdnF-3cjiC:
19.44
2hdnG-3cjiC:
9.26
2hdnH-3cjiC:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 169
ILE A 217
TRP A 140
None
1.12A 2nodB-3cjiA:
undetectable
2nodB-3cjiA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG B 178
SER B 175
TYR B 111
None
1.03A 2q2hA-3cjiB:
undetectable
2q2hB-3cjiB:
undetectable
2q2hA-3cjiB:
20.92
2q2hB-3cjiB:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 8 THR A  80
THR A 216
VAL A 237
ILE A 239
None
0.67A 2qbmA-3cjiA:
undetectable
2qbmA-3cjiA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 4 LEU C  90
PRO C  86
LEU C 105
ARG C 273
None
1.42A 2qd2A-3cjiC:
undetectable
2qd2A-3cjiC:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 5 PRO B 174
ILE B 172
ARG B 178
ASP B 191
None
1.42A 2rhmB-3cjiB:
undetectable
2rhmB-3cjiB:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 5 PRO B 174
ILE B 172
ARG B 178
ASP B 191
None
1.40A 2rhmD-3cjiB:
undetectable
2rhmD-3cjiB:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 6 LEU A 113
ALA B 103
LEU B 100
ALA B  48
None
0.92A 2vcvB-3cjiA:
undetectable
2vcvB-3cjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 6 LEU A 113
ALA B 103
LEU B 100
ALA B  48
None
0.98A 2vcvK-3cjiA:
undetectable
2vcvK-3cjiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 6 TYR B  69
TYR B  72
PHE B 217
LEU C 243
None
1.17A 2w98A-3cjiB:
undetectable
2w98B-3cjiB:
undetectable
2w98A-3cjiB:
22.22
2w98B-3cjiB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 12 LEU A 191
VAL A 193
TRP A 214
VAL A 125
TYR A 241
None
1.49A 2y00A-3cjiA:
undetectable
2y00A-3cjiA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 12 VAL A 237
LEU A  43
SER A  83
PHE A  72
THR A 216
None
1.14A 3bjwF-3cjiA:
undetectable
3bjwF-3cjiA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 169
ILE A 217
TRP A 140
None
1.04A 3e68A-3cjiA:
undetectable
3e68A-3cjiA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 169
ILE A 217
TRP A 140
None
1.06A 3e6tB-3cjiA:
undetectable
3e6tB-3cjiA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 169
ILE A 217
TRP A 140
None
1.11A 3e7iB-3cjiA:
undetectable
3e7iB-3cjiA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)
3cji POLYPROTEIN
POLYPROTEIN
POLYPROTEIN

(Senecavirus
A;
Senecavirus
A;
Senecavirus
A)
5 / 12 GLN C  17
THR C  15
GLN C 205
LEU D  71
THR A   7
None
1.18A 3fsuA-3cjiC:
undetectable
3fsuA-3cjiC:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)
3cji POLYPROTEIN
POLYPROTEIN

(Senecavirus
A;
Senecavirus
A)
4 / 8 LEU C 141
SER A 250
GLY C 190
PRO C 191
None
1.11A 3hcrA-3cjiC:
undetectable
3hcrA-3cjiC:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 12 PRO A 192
VAL A 190
TYR B  36
GLU C 138
ILE C 222
None
1.41A 3q5pA-3cjiA:
undetectable
3q5pA-3cjiA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
3cji POLYPROTEIN
POLYPROTEIN

(Senecavirus
A;
Senecavirus
A)
4 / 4 VAL B 237
PHE A 108
PHE A 110
VAL A 193
None
1.06A 3rv5C-3cjiB:
undetectable
3rv5D-3cjiB:
undetectable
3rv5C-3cjiB:
17.78
3rv5D-3cjiB:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 PRO C  53
THR C  54
LEU C 272
None
0.57A 3ttrA-3cjiC:
undetectable
3ttrA-3cjiC:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 7 ILE B  85
PHE B  56
MET B  54
PHE B 194
None
1.22A 3tvxB-3cjiB:
undetectable
3tvxB-3cjiB:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 12 GLY A 197
GLY A 196
THR C 237
LEU C 141
GLY C 223
None
0.96A 3vasA-3cjiA:
undetectable
3vasA-3cjiA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 8 GLN C 120
GLN C 118
ASN C  25
THR C  16
None
1.03A 4d1yA-3cjiC:
undetectable
4d1yB-3cjiC:
undetectable
4d1yA-3cjiC:
22.01
4d1yB-3cjiC:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 194
THR C 169
TRP C 189
None
1.11A 4d7hA-3cjiA:
undetectable
4d7hA-3cjiA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 9 VAL A 127
VAL A 128
GLU A 131
VAL A  48
ILE A  46
None
1.02A 4fwdA-3cjiA:
undetectable
4fwdA-3cjiA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 6 VAL A 127
VAL A 235
ILE A  46
LEU A  75
None
0.92A 4l1wB-3cjiA:
undetectable
4l1wB-3cjiA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
3cji POLYPROTEIN
POLYPROTEIN

(Senecavirus
A;
Senecavirus
A)
3 / 3 ASN A 243
ASP A  38
ASP B  20
None
0.81A 4obwD-3cjiA:
undetectable
4obwD-3cjiA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 12 GLY A   8
ILE C 206
ILE B  50
LEU B  53
ILE B 214
None
1.09A 4pd4C-3cjiA:
undetectable
4pd4C-3cjiA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 8 MET C 111
PHE C 269
ARG C 107
ALA C 103
None
1.01A 4rkuA-3cjiC:
undetectable
4rkuJ-3cjiC:
undetectable
4rkuA-3cjiC:
16.76
4rkuJ-3cjiC:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))
3cji POLYPROTEIN
(Senecavirus
A)
4 / 7 PRO A 192
GLU C 138
SER A 189
THR D  37
None
1.21A 4uacA-3cjiA:
undetectable
4uacA-3cjiA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 194
THR C 169
TRP C 189
None
1.09A 4uglA-3cjiA:
undetectable
4uglA-3cjiA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 7 VAL A 235
ILE A  46
LEU A 182
LEU A  75
None
0.98A 4xo7A-3cjiA:
undetectable
4xo7A-3cjiA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)
3cji POLYPROTEIN
POLYPROTEIN

(Senecavirus
A;
Senecavirus
A)
3 / 3 ASN B 107
SER B 106
ARG A 255
None
0.97A 5b2qA-3cjiB:
undetectable
5b2qA-3cjiB:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 8 PHE A 119
ALA A 114
PRO A  77
LEU A 191
None
1.06A 5dzkd-3cjiA:
undetectable
5dzkr-3cjiA:
undetectable
5dzkd-3cjiA:
23.21
5dzkr-3cjiA:
4.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 8 PHE A 119
ALA A 114
PRO A  77
LEU A 191
None
1.07A 5dzkF-3cjiA:
undetectable
5dzkT-3cjiA:
undetectable
5dzkF-3cjiA:
23.21
5dzkT-3cjiA:
4.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
3cji POLYPROTEIN
(Senecavirus
A)
4 / 7 PHE B 131
PHE B 121
GLY B 129
LEU B 204
None
1.01A 5esmA-3cjiB:
undetectable
5esmA-3cjiB:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 ARG A 194
THR C 169
TRP C 189
None
1.12A 5g6cA-3cjiA:
undetectable
5g6cA-3cjiA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 THR A  80
PRO A 192
ARG A 194
None
0.87A 5nd7B-3cjiA:
undetectable
5nd7B-3cjiA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)
3cji POLYPROTEIN
(Senecavirus
A)
3 / 3 THR A 205
PRO A 192
ARG A 194
None
0.63A 5nd7B-3cjiA:
undetectable
5nd7B-3cjiA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)
3cji POLYPROTEIN
POLYPROTEIN

(Senecavirus
A;
Senecavirus
A)
4 / 7 GLY A 196
GLY A 207
GLU C 138
THR C 225
None
0.66A 5ybbB-3cjiA:
undetectable
5ybbB-3cjiA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 12 TYR A 111
TYR A 241
PHE A 119
LEU A 191
ALA A 114
None
1.23A 5zwrA-3cjiA:
undetectable
5zwrA-3cjiA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)
3cji POLYPROTEIN
(Senecavirus
A)
5 / 12 TYR A 111
TYR A 241
PHE A 119
LEU A 191
ALA A 114
None
1.20A 5zwrB-3cjiA:
undetectable
5zwrB-3cjiA:
21.70