SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cjm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
7 / 12 ALA A 107
SER A 108
LYS A 111
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
None
0.28A 1ghmA-3cjmA:
25.5
1ghmA-3cjmA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
7 / 12 ALA A 107
SER A 108
LYS A 111
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
None
0.39A 1i2wA-3cjmA:
26.2
1i2wA-3cjmA:
28.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
7 / 12 ALA A 107
SER A 108
LYS A 111
SER A 169
ASN A 171
GLY A 259
ARG A 244
None
NO3  A   1 (-2.9A)
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
EDO  A   6 ( 4.5A)
0.94A 1i2wB-3cjmA:
26.1
1i2wB-3cjmA:
28.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
7 / 12 SER A 108
LYS A 111
SER A 169
ASN A 171
LYS A 257
GLY A 259
ASP A 262
NO3  A   1 (-2.9A)
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
None
None
0.57A 1ymxA-3cjmA:
27.5
1ymxA-3cjmA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
8 / 12 SER A 108
LYS A 111
SER A 169
ASN A 171
LYS A 257
GLY A 259
SER A 260
ASP A 262
NO3  A   1 (-2.9A)
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
None
EDO  A   7 ( 4.0A)
None
0.66A 1ymxB-3cjmA:
27.4
1ymxB-3cjmA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
3 / 3 LYS A 198
ASP A 267
ASP A 211
None
1.00A 2br4D-3cjmA:
undetectable
2br4D-3cjmA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 12 LYS A 198
GLU A 103
ASP A 267
ASP A 211
ALA A 212
None
0.99A 2br4E-3cjmA:
undetectable
2br4E-3cjmA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 11 SER A 108
THR A 145
SER A 169
GLY A 259
SER A 260
NO3  A   1 (-2.9A)
EDO  A   7 ( 4.9A)
None
None
EDO  A   7 ( 4.0A)
0.60A 2xf3A-3cjmA:
22.0
2xf3A-3cjmA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 11 SER A 108
THR A 145
SER A 169
GLY A 259
SER A 260
NO3  A   1 (-2.9A)
EDO  A   7 ( 4.9A)
None
None
EDO  A   7 ( 4.0A)
0.59A 2xf3B-3cjmA:
21.9
2xf3B-3cjmA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 LYS A 111
SER A 169
ASN A 171
LYS A 257
GLY A 259
SER A 260
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
None
EDO  A   7 ( 4.0A)
0.64A 3hlwA-3cjmA:
27.5
3hlwA-3cjmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 LYS A 111
ASN A 171
LYS A 257
GLY A 259
SER A 260
ASP A 262
NO3  A   1 (-3.5A)
NO3  A   1 ( 4.7A)
None
None
EDO  A   7 ( 4.0A)
None
0.74A 3huoA-3cjmA:
27.3
3huoA-3cjmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 LYS A 111
ASN A 171
LYS A 257
GLY A 259
SER A 260
ASP A 262
NO3  A   1 (-3.5A)
NO3  A   1 ( 4.7A)
None
None
EDO  A   7 ( 4.0A)
None
0.75A 3huoB-3cjmA:
27.5
3huoB-3cjmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 ALA A 107
SER A 108
LYS A 111
ASN A 171
GLY A 259
ARG A 244
None
NO3  A   1 (-2.9A)
NO3  A   1 (-3.5A)
NO3  A   1 ( 4.7A)
None
EDO  A   6 ( 4.5A)
0.68A 3mzeA-3cjmA:
20.8
3mzeA-3cjmA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 9 ASP A 234
ILE A 232
GLY A 269
PRO A 113
ILE A 166
None
1.02A 3nu4A-3cjmA:
undetectable
3nu4A-3cjmA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 SER A 108
SER A 169
ARG A 244
LYS A 257
GLY A 259
ASP A 262
NO3  A   1 (-2.9A)
None
EDO  A   6 ( 4.5A)
None
None
None
0.82A 3ny4A-3cjmA:
25.8
3ny4A-3cjmA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
3 / 3 TYR A 150
GLY A 146
ASP A 170
None
0.58A 3ou6C-3cjmA:
undetectable
3ou6C-3cjmA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 10 TYR A 229
ILE A 232
MET A 236
TYR A 220
ILE A 270
None
1.17A 3p4wD-3cjmA:
undetectable
3p4wD-3cjmA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 10 TYR A 229
ILE A 232
MET A 236
TYR A 220
ILE A 270
None
1.17A 3p4wE-3cjmA:
undetectable
3p4wE-3cjmA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 LYS A 111
SER A 169
ASN A 171
GLY A 259
SER A 260
ASP A 262
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
EDO  A   7 ( 4.0A)
None
0.74A 3q07A-3cjmA:
27.4
3q07A-3cjmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 LYS A 111
SER A 169
ASN A 171
LYS A 257
GLY A 259
ASP A 262
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
None
None
0.54A 3q07A-3cjmA:
27.4
3q07A-3cjmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
7 / 12 LYS A 111
SER A 169
ASN A 171
LYS A 257
GLY A 259
SER A 260
ASP A 262
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
None
EDO  A   7 ( 4.0A)
None
0.67A 3q07B-3cjmA:
27.3
3q07B-3cjmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 ALA A 107
SER A 108
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
None
0.25A 3sh8A-3cjmA:
26.7
3sh8A-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
7 / 12 ALA A 107
SER A 108
LYS A 111
SER A 169
ASN A 171
GLY A 259
ARG A 244
None
NO3  A   1 (-2.9A)
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
EDO  A   6 ( 4.5A)
0.96A 3sh8B-3cjmA:
26.5
3sh8B-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
7 / 12 ALA A 107
SER A 108
LYS A 111
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
NO3  A   1 (-3.5A)
None
NO3  A   1 ( 4.7A)
None
None
0.28A 3sh8B-3cjmA:
26.5
3sh8B-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 12 LEU A 219
LEU A 216
LEU A 213
ALA A 212
MET A 236
None
1.25A 4fn9B-3cjmA:
undetectable
4fn9B-3cjmA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
3 / 3 ILE A  85
MET A 245
ARG A 244
None
None
EDO  A   6 ( 4.5A)
0.87A 4lnwA-3cjmA:
undetectable
4lnwA-3cjmA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
3 / 3 ILE A  85
MET A 245
ARG A 244
None
None
EDO  A   6 ( 4.5A)
0.87A 4lnxA-3cjmA:
undetectable
4lnxA-3cjmA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 ALA A 107
SER A 108
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
None
0.31A 4n9kA-3cjmA:
26.8
4n9kA-3cjmA:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 ALA A 107
SER A 108
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
None
0.32A 4n9kB-3cjmA:
26.7
4n9kB-3cjmA:
28.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
4 / 7 GLU A  91
TYR A  87
LEU A 302
TYR A 310
None
1.09A 4twdF-3cjmA:
2.0
4twdJ-3cjmA:
undetectable
4twdF-3cjmA:
23.30
4twdJ-3cjmA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
4 / 5 THR A 106
ALA A 107
THR A 109
HIS A 266
None
1.30A 5ecmA-3cjmA:
undetectable
5ecmA-3cjmA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 ALA A 107
SER A 108
SER A 169
ASN A 171
GLY A 259
ARG A 244
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
EDO  A   6 ( 4.5A)
1.01A 5ghyA-3cjmA:
26.8
5ghyA-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 ALA A 107
SER A 108
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
None
0.31A 5ghyA-3cjmA:
26.8
5ghyA-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 ALA A 107
SER A 108
SER A 169
ASN A 171
GLY A 259
ARG A 244
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
EDO  A   6 ( 4.5A)
1.01A 5ghyB-3cjmA:
26.7
5ghyB-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 ALA A 107
SER A 108
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
None
0.28A 5ghyB-3cjmA:
26.7
5ghyB-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 11 ALA A 107
SER A 108
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
None
0.30A 5ghzA-3cjmA:
26.7
5ghzA-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 10 ALA A 107
SER A 108
SER A 169
ASN A 171
LYS A 257
GLY A 259
None
NO3  A   1 (-2.9A)
None
NO3  A   1 ( 4.7A)
None
None
0.29A 5ghzB-3cjmA:
26.9
5ghzB-3cjmA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 SER A 108
SER A 169
ARG A 244
LYS A 257
GLY A 259
ASP A 262
NO3  A   1 (-2.9A)
None
EDO  A   6 ( 4.5A)
None
None
None
0.64A 6b5yB-3cjmA:
26.1
6b5yB-3cjmA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 SER A 108
SER A 169
ARG A 244
LYS A 257
GLY A 259
ASP A 262
NO3  A   1 (-2.9A)
None
EDO  A   6 ( 4.5A)
None
None
None
0.59A 6b68D-3cjmA:
26.0
6b68D-3cjmA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 SER A 108
SER A 169
ARG A 244
LYS A 257
GLY A 259
ASP A 262
NO3  A   1 (-2.9A)
None
EDO  A   6 ( 4.5A)
None
None
None
0.61A 6b6aB-3cjmA:
26.2
6b6aB-3cjmA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
6 / 12 SER A 108
SER A 169
ARG A 244
LYS A 257
GLY A 259
ASP A 262
NO3  A   1 (-2.9A)
None
EDO  A   6 ( 4.5A)
None
None
None
0.63A 6b6aD-3cjmA:
25.9
6b6aD-3cjmA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 12 SER A 108
SER A 169
ARG A 244
LYS A 257
GLY A 259
NO3  A   1 (-2.9A)
None
EDO  A   6 ( 4.5A)
None
None
0.37A 6b6cA-3cjmA:
26.1
6b6cA-3cjmA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 12 SER A 169
ASN A 171
LYS A 257
GLY A 259
SER A 260
None
NO3  A   1 ( 4.7A)
None
None
EDO  A   7 ( 4.0A)
0.59A 6c79A-3cjmA:
27.4
6c79A-3cjmA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 11 VAL A  76
GLY A  84
SER A 209
ALA A 212
ASN A  69
EDO  A   3 ( 4.7A)
None
None
None
None
1.44A 6hu9A-3cjmA:
undetectable
6hu9E-3cjmA:
0.1
6hu9I-3cjmA:
undetectable
6hu9A-3cjmA:
21.07
6hu9E-3cjmA:
22.59
6hu9I-3cjmA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
3cjm PUTATIVE
BETA-LACTAMASE

(Enterococcus
faecalis)
5 / 10 VAL A  76
GLY A  84
SER A 209
ALA A 212
ASN A  69
EDO  A   3 ( 4.7A)
None
None
None
None
1.42A 6hu9L-3cjmA:
undetectable
6hu9P-3cjmA:
undetectable
6hu9T-3cjmA:
undetectable
6hu9L-3cjmA:
21.07
6hu9P-3cjmA:
22.59
6hu9T-3cjmA:
14.39