SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cjn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1103_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3cjn TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Ruegeria
pomeroyi) 		4 / 5 ASN A  37
ARG A  39
HIS A 123
LEU A 120
 None
 1.00A 4g5jA-3cjnA:
0.0		 4g5jA-3cjnA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3cjn TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Ruegeria
pomeroyi) 		4 / 7 LEU A 144
ASN A 148
MET A 131
ILE A 154
 None
 1.04A 4okwA-3cjnA:
undetectable		 4okwA-3cjnA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 3cjn TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Ruegeria
pomeroyi) 		3 / 3 LEU A  38
ARG A  39
ARG A  53
 None
 0.81A 4yiaB-3cjnA:
undetectable		 4yiaB-3cjnA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_J_4LEJ401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3cjn TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Ruegeria
pomeroyi) 		6 / 9 ALA A  73
LEU A  69
LEU A  84
ALA A  83
LEU A  87
LEU A  55
 None
 1.12A 4z91F-3cjnA:
undetectable
4z91G-3cjnA:
undetectable
4z91H-3cjnA:
undetectable
4z91I-3cjnA:
undetectable
4z91J-3cjnA:
undetectable		 4z91F-3cjnA:
22.08
4z91G-3cjnA:
22.08
4z91H-3cjnA:
22.08
4z91I-3cjnA:
22.08
4z91J-3cjnA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 3cjn TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Ruegeria
pomeroyi) 		4 / 6 LEU A  87
LEU A  84
SER A  81
THR A  79
 None
 1.28A 5l4iB-3cjnA:
undetectable		 5l4iB-3cjnA:
20.69