SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cjs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 3cjs 50S RIBOSOMAL
PROTEIN L11
RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 PHE B  41
PHE B  37
PHE A  21
LEU A  17
LEU A  10
 None
 1.09A 1dtlA-3cjsB:
undetectable		 1dtlA-3cjsB:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 3cjs RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Thermus
thermophilus) 		3 / 3 PHE A  39
VAL A  43
TRP A  51
 None
 0.68A 2cc8A-3cjsA:
undetectable		 2cc8A-3cjsA:
27.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 3cjs RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Thermus
thermophilus) 		3 / 3 PHE A  39
VAL A  43
TRP A  51
 None
 0.67A 2ccbA-3cjsA:
undetectable		 2ccbA-3cjsA:
27.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 3cjs 50S RIBOSOMAL
PROTEIN L11
RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 ILE B  34
VAL B   8
TRP A  29
LEU B  10
MET A   1
 None
 1.40A 2jj8C-3cjsB:
undetectable		 2jj8C-3cjsB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 3cjs RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Thermus
thermophilus) 		3 / 3 PHE A  39
VAL A  43
TRP A  51
 None
 0.68A 2vx9A-3cjsA:
undetectable		 2vx9A-3cjsA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 3cjs RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 4 VAL A  35
GLU A  30
GLY A   8
LEU A  13
 None
 1.36A 5g5gC-3cjsA:
undetectable		 5g5gC-3cjsA:
6.32