SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DBB_H_STRH229_1 (IGG1-KAPPA DB3 FAB (HEAVY CHAIN) IGG1-KAPPA DB3 FAB (LIGHT CHAIN))	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	4 / 8	GLY A 102 GLY A 100 HIS A 197 VAL A 189	None SAH A 258 (-3.1A) None None	0.86A	1dbbH-3cjtA: undetectable 1dbbL-3cjtA: undetectable	1dbbH-3cjtA: 19.85 1dbbL-3cjtA: 17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QAO_A_SAMA245_0 (ERMC' METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 128 GLY A 130 ILE A 150 ASP A 151 ASN A 191	SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-4.0A) None SAH A 258 ( 3.8A)	0.47A	1qaoA-3cjtA: 11.2	1qaoA-3cjtA: 17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VQ1_A_SAMA301_1 (N5-GLUTAMINE METHYLTRANSFERASE, HEMK)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	GLY A 128 ASP A 149 ASN A 191	SAH A 258 (-3.1A) SAH A 258 (-2.8A) SAH A 258 ( 3.8A)	0.26A	1vq1A-3cjtA: 16.9	1vq1A-3cjtA: 25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CC8_A_RBFA1067_1 (VNG1446H)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	PHE A 39 VAL A 43 TRP A 51	None	0.66A	2cc8A-3cjtA: undetectable	2cc8A-3cjtA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CCB_A_RBFA1067_1 (VNG1446H)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	PHE A 39 VAL A 43 TRP A 51	None	0.66A	2ccbA-3cjtA: undetectable	2ccbA-3cjtA: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KCE_A_D16A566_1 (THYMIDYLATE SYNTHASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLU A 139 LEU A 187 GLY A 147 PHE A 171 ALA A 190	None	1.36A	2kceA-3cjtA: undetectable	2kceA-3cjtA: 22.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	ASP A 126 LEU A 127 GLY A 128 LEU A 134 ILE A 150 LEU A 200	SAH A 258 ( 3.9A) None SAH A 258 (-3.1A) SAH A 258 (-4.2A) SAH A 258 (-4.0A) None	1.16A	2nxeA-3cjtA: 37.5	2nxeA-3cjtA: 99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2NXE_A_SAMA302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	12 / 12	PHE A 99 GLY A 100 ASP A 126 LEU A 127 GLY A 128 GLY A 130 LEU A 134 ILE A 150 ASP A 151 ASN A 191 LEU A 192 LEU A 196	SAH A 258 ( 4.3A) SAH A 258 (-3.1A) SAH A 258 ( 3.9A) None SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-4.2A) SAH A 258 (-4.0A) None SAH A 258 ( 3.8A) None SAH A 258 (-4.6A)	0.26A	2nxeA-3cjtA: 37.5	2nxeA-3cjtA: 99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2NXE_A_SAMA302_1 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	THR A 107 ASP A 149 SER A 175	SAH A 258 (-2.9A) SAH A 258 (-2.8A) SAH A 258 (-2.6A)	0.12A	2nxeA-3cjtA: 37.5	2nxeA-3cjtA: 99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	12 / 12	PHE A 99 GLY A 100 ASP A 126 LEU A 127 GLY A 128 GLY A 130 LEU A 134 ILE A 150 ASP A 151 ASN A 191 LEU A 192 LEU A 196	SAH A 258 ( 4.3A) SAH A 258 (-3.1A) SAH A 258 ( 3.9A) None SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-4.2A) SAH A 258 (-4.0A) None SAH A 258 ( 3.8A) None SAH A 258 (-4.6A)	0.26A	2nxeB-3cjtA: 38.3	2nxeB-3cjtA: 99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2NXE_B_SAMB303_1 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	THR A 107 ASP A 149 SER A 175	SAH A 258 (-2.9A) SAH A 258 (-2.8A) SAH A 258 (-2.6A)	0.13A	2nxeB-3cjtA: 38.3	2nxeB-3cjtA: 99.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_D_ASDD1223_1 (GLUTATHIONE S-TRANSFERASE A2)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	4 / 7	ILE A 136 GLY A 132 LEU A 155 PHE A 171	None	1.00A	2vctD-3cjtA: undetectable	2vctD-3cjtA: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VX9_A_RBFA1064_1 (DODECIN)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	3 / 3	PHE A 39 VAL A 43 TRP A 51	None	0.67A	2vx9A-3cjtA: undetectable	2vx9A-3cjtA: 12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X7H_B_PFNB1374_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	4 / 4	TYR A 204 LEU A 125 LEU A 127 HIS A 197	None	1.22A	2x7hB-3cjtA: 9.7	2x7hB-3cjtA: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X7H_B_PFNB1374_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	4 / 4	TYR A 204 LEU A 208 LEU A 188 HIS A 197	None	1.27A	2x7hB-3cjtA: 9.7	2x7hB-3cjtA: 22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN3_A_ID8A1356_1 (THYROXINE-BINDING GLOBULIN)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	4 / 8	LEU A 6 LYS A 7 LEU A 10 ARG A 5	None	1.18A	2xn3A-3cjtA: undetectable 2xn3B-3cjtA: undetectable	2xn3A-3cjtA: 21.95 2xn3B-3cjtA: 8.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ZBP_A_SAMA300_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	12 / 12	PHE A 99 GLY A 100 LEU A 127 GLY A 128 GLY A 130 LEU A 134 ILE A 150 ASP A 151 SER A 175 ASN A 191 LEU A 192 LEU A 196	SAH A 258 ( 4.3A) SAH A 258 (-3.1A) None SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-4.2A) SAH A 258 (-4.0A) None SAH A 258 (-2.6A) SAH A 258 ( 3.8A) None SAH A 258 (-4.6A)	0.31A	2zbpA-3cjtA: 37.1	2zbpA-3cjtA: 99.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	PHE A 99 GLY A 128 GLY A 130 LEU A 134 ASN A 191	SAH A 258 ( 4.3A) SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-4.2A) SAH A 258 ( 3.8A)	0.44A	2zulA-3cjtA: 18.4	2zulA-3cjtA: 27.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CJT_C_SAMC302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	11 / 12	ASP A 126 LEU A 127 GLY A 128 VAL A 133 LEU A 134 ASP A 149 ILE A 150 ASP A 151 SER A 175 LEU A 192 LEU A 196	SAH A 258 ( 3.9A) None SAH A 258 (-3.1A) None SAH A 258 (-4.2A) SAH A 258 (-2.8A) SAH A 258 (-4.0A) None SAH A 258 (-2.6A) None SAH A 258 (-4.6A)	0.27A	3cjtC-3cjtA: 34.5	3cjtC-3cjtA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CJT_C_SAMC302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	8 / 12	ASP A 126 LEU A 127 GLY A 128 VAL A 133 LEU A 134 ILE A 150 SER A 175 LEU A 200	SAH A 258 ( 3.9A) None SAH A 258 (-3.1A) None SAH A 258 (-4.2A) SAH A 258 (-4.0A) SAH A 258 (-2.6A) None	1.38A	3cjtC-3cjtA: 34.5	3cjtC-3cjtA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CJT_G_SAMG302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	11 / 12	LEU A 127 GLY A 128 GLY A 130 SER A 131 VAL A 133 LEU A 134 ILE A 150 ASP A 151 ASN A 191 LEU A 192 LEU A 196	None SAH A 258 (-3.1A) SAH A 258 (-3.6A) None None SAH A 258 (-4.2A) SAH A 258 (-4.0A) None SAH A 258 ( 3.8A) None SAH A 258 (-4.6A)	0.34A	3cjtG-3cjtA: 34.4	3cjtG-3cjtA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CJT_K_SAMK302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	11 / 12	LEU A 127 GLY A 128 SER A 131 VAL A 133 LEU A 134 ILE A 150 ASP A 151 SER A 175 ASN A 191 LEU A 192 LEU A 196	None SAH A 258 (-3.1A) None None SAH A 258 (-4.2A) SAH A 258 (-4.0A) None SAH A 258 (-2.6A) SAH A 258 ( 3.8A) None SAH A 258 (-4.6A)	0.34A	3cjtK-3cjtA: 31.2	3cjtK-3cjtA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	11 / 12	LEU A 127 GLY A 128 GLY A 130 SER A 131 VAL A 133 LEU A 134 ILE A 150 ASP A 151 ASN A 191 LEU A 192 LEU A 196	None SAH A 258 (-3.1A) SAH A 258 (-3.6A) None None SAH A 258 (-4.2A) SAH A 258 (-4.0A) None SAH A 258 ( 3.8A) None SAH A 258 (-4.6A)	0.35A	3cjtO-3cjtA: 31.3	3cjtO-3cjtA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	LEU A 127 GLY A 128 VAL A 133 LEU A 134 ILE A 150 LEU A 200	None SAH A 258 (-3.1A) None SAH A 258 (-4.2A) SAH A 258 (-4.0A) None	1.46A	3cjtO-3cjtA: 31.3	3cjtO-3cjtA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	7 / 12	LEU A 192 GLY A 128 GLY A 130 SER A 131 VAL A 133 ILE A 150 ASP A 151	None SAH A 258 (-3.1A) SAH A 258 (-3.6A) None None SAH A 258 (-4.0A) None	1.46A	3cjtO-3cjtA: 31.3	3cjtO-3cjtA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DMH_A_SAMA384_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	PHE A 99 GLY A 128 GLY A 130 LEU A 134 ASN A 191	SAH A 258 ( 4.3A) SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-4.2A) SAH A 258 ( 3.8A)	0.45A	3dmhA-3cjtA: 18.5	3dmhA-3cjtA: 27.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GRV_A_ADNA300_1 (DIMETHYLADENOSINE TRANSFERASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 11	GLY A 128 GLY A 130 ILE A 150 ASP A 151 ASN A 191	SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-4.0A) None SAH A 258 ( 3.8A)	0.71A	3grvA-3cjtA: 13.7	3grvA-3cjtA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DCM_A_SAMA401_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE G)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	6 / 11	PHE A 99 ASP A 126 GLY A 128 GLY A 130 ASP A 149 ASN A 191	SAH A 258 ( 4.3A) SAH A 258 ( 3.9A) SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-2.8A) SAH A 258 ( 3.8A)	0.40A	4dcmA-3cjtA: 17.7	4dcmA-3cjtA: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DU2_A_LDPA501_1 (CYTOCHROME P450 BM3 VARIANT B7)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	4 / 7	ALA A 137 ALA A 110 PRO A 74 LEU A 114	None	0.88A	4du2A-3cjtA: undetectable	4du2A-3cjtA: 21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4POO_B_SAMB301_0 (PUTATIVE RNA METHYLASE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 130 ASP A 149 ILE A 150 SER A 175 ASN A 191	SAH A 258 (-3.6A) SAH A 258 (-2.8A) SAH A 258 (-4.0A) SAH A 258 (-2.6A) SAH A 258 ( 3.8A)	0.55A	4pooB-3cjtA: 15.0	4pooB-3cjtA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G5G_C_ACTC1740_0 (PUTATIVE XANTHINE DEHYDROGENASE YAGS FAD-BINDING SUBUNIT)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	4 / 4	VAL A 35 GLU A 30 GLY A 8 LEU A 13	None	1.36A	5g5gC-3cjtA: undetectable	5g5gC-3cjtA: 17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WY0_A_SAMA800_0 (SMALL RNA 2'-O-METHYLTRANSFERA SE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 128 GLY A 130 ASP A 149 ILE A 150 LEU A 192	SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-2.8A) SAH A 258 (-4.0A) None	0.63A	5wy0A-3cjtA: 11.4	5wy0A-3cjtA: 23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WY0_A_SAMA800_0 (SMALL RNA 2'-O-METHYLTRANSFERA SE)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 12	GLY A 128 GLY A 130 ASP A 149 ILE A 150 LEU A 196	SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 (-2.8A) SAH A 258 (-4.0A) SAH A 258 (-4.6A)	0.60A	5wy0A-3cjtA: 11.4	5wy0A-3cjtA: 23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_A_ADNA401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	7 / 12	GLY A 128 ASP A 149 ILE A 150 ASP A 151 VAL A 154 LEU A 192 LEU A 196	SAH A 258 (-3.1A) SAH A 258 (-2.8A) SAH A 258 (-4.0A) None None None SAH A 258 (-4.6A)	1.05A	6bq4A-3cjtA: 12.9	6bq4A-3cjtA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_B_ADNB401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	6 / 12	GLY A 128 ASP A 149 ILE A 150 ASP A 151 VAL A 154 LEU A 192	SAH A 258 (-3.1A) SAH A 258 (-2.8A) SAH A 258 (-4.0A) None None None	0.89A	6bq4B-3cjtA: 13.0	6bq4B-3cjtA: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NQA_K_SAMK500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	3cjt	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE (Thermus thermophilus)	5 / 10	THR A 107 ASP A 126 GLY A 128 GLY A 130 ASN A 191	SAH A 258 (-2.9A) SAH A 258 ( 3.9A) SAH A 258 (-3.1A) SAH A 258 (-3.6A) SAH A 258 ( 3.8A)	0.97A	6nqaK-3cjtA: 8.5	6nqaK-3cjtA: 20.20

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DBB_H_STRH229_1","IGG1-KAPPA DB3 FAB (HEAVY CHAIN);IGG1-KAPPA DB3 FAB (LIGHT CHAIN)","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",4,"GLY A 102;GLY A 100;HIS A 197;VAL A 189","None;SAH A 258 (-3.1A);None;None","0.86A","1dbbH-3cjtA:undetectable;1dbbL-3cjtA:undetectable","1dbbH-3cjtA:19.85;1dbbL-3cjtA:17.87"],["1QAO_A_SAMA245_0","ERMC' METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 128;GLY A 130;ILE A 150;ASP A 151;ASN A 191","SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-4.0A);None;SAH A 258 ( 3.8A)","0.47A","1qaoA-3cjtA:11.2","1qaoA-3cjtA:17.27"],["1VQ1_A_SAMA301_1","N5-GLUTAMINE METHYLTRANSFERASE, HEMK","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",3,"GLY A 128;ASP A 149;ASN A 191","SAH A 258 (-3.1A);SAH A 258 (-2.8A);SAH A 258 ( 3.8A)","0.26A","1vq1A-3cjtA:16.9","1vq1A-3cjtA:25.16"],["2CC8_A_RBFA1067_1","VNG1446H","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",3,"PHE A  39;VAL A  43;TRP A  51","None","0.66A","2cc8A-3cjtA:undetectable","2cc8A-3cjtA:16.29"],["2CCB_A_RBFA1067_1","VNG1446H","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",3,"PHE A  39;VAL A  43;TRP A  51","None","0.66A","2ccbA-3cjtA:undetectable","2ccbA-3cjtA:16.29"],["2KCE_A_D16A566_1","THYMIDYLATE SYNTHASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"GLU A 139;LEU A 187;GLY A 147;PHE A 171;ALA A 190","None","1.36A","2kceA-3cjtA:undetectable","2kceA-3cjtA:22.92"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",6,"ASP A 126;LEU A 127;GLY A 128;LEU A 134;ILE A 150;LEU A 200","SAH A 258 ( 3.9A);None;SAH A 258 (-3.1A);SAH A 258 (-4.2A);SAH A 258 (-4.0A);None","1.16A","2nxeA-3cjtA:37.5","2nxeA-3cjtA:99.61"],["2NXE_A_SAMA302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",12,"PHE A  99;GLY A 100;ASP A 126;LEU A 127;GLY A 128;GLY A 130;LEU A 134;ILE A 150;ASP A 151;ASN A 191;LEU A 192;LEU A 196","SAH A 258 ( 4.3A);SAH A 258 (-3.1A);SAH A 258 ( 3.9A);None;SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-4.2A);SAH A 258 (-4.0A);None;SAH A 258 ( 3.8A);None;SAH A 258 (-4.6A)","0.26A","2nxeA-3cjtA:37.5","2nxeA-3cjtA:99.61"],["2NXE_A_SAMA302_1","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",3,"THR A 107;ASP A 149;SER A 175","SAH A 258 (-2.9A);SAH A 258 (-2.8A);SAH A 258 (-2.6A)","0.12A","2nxeA-3cjtA:37.5","2nxeA-3cjtA:99.61"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",12,"PHE A  99;GLY A 100;ASP A 126;LEU A 127;GLY A 128;GLY A 130;LEU A 134;ILE A 150;ASP A 151;ASN A 191;LEU A 192;LEU A 196","SAH A 258 ( 4.3A);SAH A 258 (-3.1A);SAH A 258 ( 3.9A);None;SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-4.2A);SAH A 258 (-4.0A);None;SAH A 258 ( 3.8A);None;SAH A 258 (-4.6A)","0.26A","2nxeB-3cjtA:38.3","2nxeB-3cjtA:99.61"],["2NXE_B_SAMB303_1","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",3,"THR A 107;ASP A 149;SER A 175","SAH A 258 (-2.9A);SAH A 258 (-2.8A);SAH A 258 (-2.6A)","0.13A","2nxeB-3cjtA:38.3","2nxeB-3cjtA:99.61"],["2VCT_D_ASDD1223_1","GLUTATHIONE S-TRANSFERASE A2","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",4,"ILE A 136;GLY A 132;LEU A 155;PHE A 171","None","1.00A","2vctD-3cjtA:undetectable","2vctD-3cjtA:23.16"],["2VX9_A_RBFA1064_1","DODECIN","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",3,"PHE A  39;VAL A  43;TRP A  51","None","0.67A","2vx9A-3cjtA:undetectable","2vx9A-3cjtA:12.20"],["2X7H_B_PFNB1374_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",4,"TYR A 204;LEU A 125;LEU A 127;HIS A 197","None","1.22A","2x7hB-3cjtA:9.7","2x7hB-3cjtA:22.11"],["2X7H_B_PFNB1374_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",4,"TYR A 204;LEU A 208;LEU A 188;HIS A 197","None","1.27A","2x7hB-3cjtA:9.7","2x7hB-3cjtA:22.11"],["2XN3_A_ID8A1356_1","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",4,"LEU A   6;LYS A   7;LEU A  10;ARG A   5","None","1.18A","2xn3A-3cjtA:undetectable;2xn3B-3cjtA:undetectable","2xn3A-3cjtA:21.95;2xn3B-3cjtA:8.68"],["2ZBP_A_SAMA300_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",12,"PHE A  99;GLY A 100;LEU A 127;GLY A 128;GLY A 130;LEU A 134;ILE A 150;ASP A 151;SER A 175;ASN A 191;LEU A 192;LEU A 196","SAH A 258 ( 4.3A);SAH A 258 (-3.1A);None;SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-4.2A);SAH A 258 (-4.0A);None;SAH A 258 (-2.6A);SAH A 258 ( 3.8A);None;SAH A 258 (-4.6A)","0.31A","2zbpA-3cjtA:37.1","2zbpA-3cjtA:99.61"],["2ZUL_A_SAMA376_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"PHE A  99;GLY A 128;GLY A 130;LEU A 134;ASN A 191","SAH A 258 ( 4.3A);SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-4.2A);SAH A 258 ( 3.8A)","0.44A","2zulA-3cjtA:18.4","2zulA-3cjtA:27.76"],["3CJT_C_SAMC302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",11,"ASP A 126;LEU A 127;GLY A 128;VAL A 133;LEU A 134;ASP A 149;ILE A 150;ASP A 151;SER A 175;LEU A 192;LEU A 196","SAH A 258 ( 3.9A);None;SAH A 258 (-3.1A);None;SAH A 258 (-4.2A);SAH A 258 (-2.8A);SAH A 258 (-4.0A);None;SAH A 258 (-2.6A);None;SAH A 258 (-4.6A)","0.27A","3cjtC-3cjtA:34.5","3cjtC-3cjtA:100.00"],["3CJT_C_SAMC302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",8,"ASP A 126;LEU A 127;GLY A 128;VAL A 133;LEU A 134;ILE A 150;SER A 175;LEU A 200","SAH A 258 ( 3.9A);None;SAH A 258 (-3.1A);None;SAH A 258 (-4.2A);SAH A 258 (-4.0A);SAH A 258 (-2.6A);None","1.38A","3cjtC-3cjtA:34.5","3cjtC-3cjtA:100.00"],["3CJT_G_SAMG302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",11,"LEU A 127;GLY A 128;GLY A 130;SER A 131;VAL A 133;LEU A 134;ILE A 150;ASP A 151;ASN A 191;LEU A 192;LEU A 196","None;SAH A 258 (-3.1A);SAH A 258 (-3.6A);None;None;SAH A 258 (-4.2A);SAH A 258 (-4.0A);None;SAH A 258 ( 3.8A);None;SAH A 258 (-4.6A)","0.34A","3cjtG-3cjtA:34.4","3cjtG-3cjtA:100.00"],["3CJT_K_SAMK302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",11,"LEU A 127;GLY A 128;SER A 131;VAL A 133;LEU A 134;ILE A 150;ASP A 151;SER A 175;ASN A 191;LEU A 192;LEU A 196","None;SAH A 258 (-3.1A);None;None;SAH A 258 (-4.2A);SAH A 258 (-4.0A);None;SAH A 258 (-2.6A);SAH A 258 ( 3.8A);None;SAH A 258 (-4.6A)","0.34A","3cjtK-3cjtA:31.2","3cjtK-3cjtA:100.00"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",11,"LEU A 127;GLY A 128;GLY A 130;SER A 131;VAL A 133;LEU A 134;ILE A 150;ASP A 151;ASN A 191;LEU A 192;LEU A 196","None;SAH A 258 (-3.1A);SAH A 258 (-3.6A);None;None;SAH A 258 (-4.2A);SAH A 258 (-4.0A);None;SAH A 258 ( 3.8A);None;SAH A 258 (-4.6A)","0.35A","3cjtO-3cjtA:31.3","3cjtO-3cjtA:100.00"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",6,"LEU A 127;GLY A 128;VAL A 133;LEU A 134;ILE A 150;LEU A 200","None;SAH A 258 (-3.1A);None;SAH A 258 (-4.2A);SAH A 258 (-4.0A);None","1.46A","3cjtO-3cjtA:31.3","3cjtO-3cjtA:100.00"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",7,"LEU A 192;GLY A 128;GLY A 130;SER A 131;VAL A 133;ILE A 150;ASP A 151","None;SAH A 258 (-3.1A);SAH A 258 (-3.6A);None;None;SAH A 258 (-4.0A);None","1.46A","3cjtO-3cjtA:31.3","3cjtO-3cjtA:100.00"],["3DMH_A_SAMA384_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"PHE A  99;GLY A 128;GLY A 130;LEU A 134;ASN A 191","SAH A 258 ( 4.3A);SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-4.2A);SAH A 258 ( 3.8A)","0.45A","3dmhA-3cjtA:18.5","3dmhA-3cjtA:27.76"],["3GRV_A_ADNA300_1","DIMETHYLADENOSINE TRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 128;GLY A 130;ILE A 150;ASP A 151;ASN A 191","SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-4.0A);None;SAH A 258 ( 3.8A)","0.71A","3grvA-3cjtA:13.7","3grvA-3cjtA:20.83"],["4DCM_A_SAMA401_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE G","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",6,"PHE A  99;ASP A 126;GLY A 128;GLY A 130;ASP A 149;ASN A 191","SAH A 258 ( 4.3A);SAH A 258 ( 3.9A);SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-2.8A);SAH A 258 ( 3.8A)","0.40A","4dcmA-3cjtA:17.7","4dcmA-3cjtA:24.32"],["4DU2_A_LDPA501_1","CYTOCHROME P450 BM3 VARIANT B7","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",4,"ALA A 137;ALA A 110;PRO A  74;LEU A 114","None","0.88A","4du2A-3cjtA:undetectable","4du2A-3cjtA:21.72"],["4POO_B_SAMB301_0","PUTATIVE RNA METHYLASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 130;ASP A 149;ILE A 150;SER A 175;ASN A 191","SAH A 258 (-3.6A);SAH A 258 (-2.8A);SAH A 258 (-4.0A);SAH A 258 (-2.6A);SAH A 258 ( 3.8A)","0.55A","4pooB-3cjtA:15.0","4pooB-3cjtA:21.60"],["5G5G_C_ACTC1740_0","PUTATIVE XANTHINE DEHYDROGENASE YAGS FAD-BINDING SUBUNIT","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",4,"VAL A  35;GLU A  30;GLY A   8;LEU A  13","None","1.36A","5g5gC-3cjtA:undetectable","5g5gC-3cjtA:17.53"],["5WY0_A_SAMA800_0","SMALL RNA 2'-O-METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 128;GLY A 130;ASP A 149;ILE A 150;LEU A 192","SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-2.8A);SAH A 258 (-4.0A);None","0.63A","5wy0A-3cjtA:11.4","5wy0A-3cjtA:23.19"],["5WY0_A_SAMA800_0","SMALL RNA 2'-O-METHYLTRANSFERASE","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"GLY A 128;GLY A 130;ASP A 149;ILE A 150;LEU A 196","SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 (-2.8A);SAH A 258 (-4.0A);SAH A 258 (-4.6A)","0.60A","5wy0A-3cjtA:11.4","5wy0A-3cjtA:23.19"],["6BQ4_A_ADNA401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",7,"GLY A 128;ASP A 149;ILE A 150;ASP A 151;VAL A 154;LEU A 192;LEU A 196","SAH A 258 (-3.1A);SAH A 258 (-2.8A);SAH A 258 (-4.0A);None;None;None;SAH A 258 (-4.6A)","1.05A","6bq4A-3cjtA:12.9","6bq4A-3cjtA:13.64"],["6BQ4_B_ADNB401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",6,"GLY A 128;ASP A 149;ILE A 150;ASP A 151;VAL A 154;LEU A 192","SAH A 258 (-3.1A);SAH A 258 (-2.8A);SAH A 258 (-4.0A);None;None;None","0.89A","6bq4B-3cjtA:13.0","6bq4B-3cjtA:13.64"],["6NQA_K_SAMK500_0","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC","3cjt","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","Thermus thermophilus",5,"THR A 107;ASP A 126;GLY A 128;GLY A 130;ASN A 191","SAH A 258 (-2.9A);SAH A 258 ( 3.9A);SAH A 258 (-3.1A);SAH A 258 (-3.6A);SAH A 258 ( 3.8A)","0.97A","6nqaK-3cjtA:8.5","6nqaK-3cjtA:20.20"]]