SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cjx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		3 / 3 ALA A 138
VAL A 140
TRP A 144
 None
 0.91A 1micA-3cjxA:
undetectable
1micB-3cjxA:
undetectable		 1micA-3cjxA:
12.00
1micB-3cjxA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		4 / 8 TYR A 132
PHE A  63
ASN A 125
GLY A 134
 None
 1.07A 1ykiC-3cjxA:
undetectable
1ykiD-3cjxA:
undetectable		 1ykiC-3cjxA:
19.46
1ykiD-3cjxA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		3 / 3 THR A  58
PRO A 106
TYR A  78
 None
 0.84A 2dxrA-3cjxA:
undetectable		 2dxrA-3cjxA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		3 / 3 PRO A  60
LEU A  61
GLN A 102
 None
 0.57A 3hznG-3cjxA:
undetectable
3hznH-3cjxA:
undetectable		 3hznG-3cjxA:
17.89
3hznH-3cjxA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		4 / 5 ASP A 146
ILE A  35
PRO A  37
PHE A  36
 None
 0.98A 3s3vA-3cjxA:
undetectable		 3s3vA-3cjxA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		5 / 7 THR A  58
GLY A  56
PRO A 106
TYR A  78
THR A  88
 None
 1.38A 3tajA-3cjxA:
undetectable		 3tajA-3cjxA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		4 / 5 THR A  58
GLY A  56
PRO A 106
TYR A  78
 None
 0.81A 3u8qA-3cjxA:
undetectable		 3u8qA-3cjxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		4 / 6 THR A  58
GLY A  56
PRO A 106
TYR A  78
 None
 0.80A 4fjpA-3cjxA:
undetectable		 4fjpA-3cjxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		4 / 5 THR A  58
GLY A  56
PRO A 106
TYR A  78
 None
 0.82A 4grkA-3cjxA:
undetectable		 4grkA-3cjxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD
(Cupriavidus
pinatubonensis) 		4 / 8 ALA A  51
PRO A  37
LEU A  27
LEU A  24
 None
 1.21A 5dzkd-3cjxA:
undetectable
5dzkr-3cjxA:
undetectable		 5dzkd-3cjxA:
22.67
5dzkr-3cjxA:
18.18