SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ckb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_2
(GLUCOAMYLASE-471)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 SER A 265
TRP A 485
GLU A 488
LEU A 225
 None
 1.48A 1agmA-3ckbA:
undetectable		 1agmA-3ckbA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.04A 1d1vA-3ckbA:
undetectable
1d1vB-3ckbA:
undetectable		 1d1vA-3ckbA:
21.88
1d1vB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 1d1vA-3ckbA:
undetectable
1d1vB-3ckbA:
undetectable		 1d1vA-3ckbA:
21.88
1d1vB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.04A 1d1wA-3ckbA:
0.0
1d1wB-3ckbA:
undetectable		 1d1wA-3ckbA:
21.88
1d1wB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 1d1wA-3ckbA:
0.0
1d1wB-3ckbA:
undetectable		 1d1wA-3ckbA:
21.88
1d1wB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 1d1xA-3ckbA:
0.0
1d1xB-3ckbA:
0.0		 1d1xA-3ckbA:
21.88
1d1xB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 1d1xA-3ckbA:
0.0
1d1xB-3ckbA:
0.0		 1d1xA-3ckbA:
21.88
1d1xB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 1dm8A-3ckbA:
0.0
1dm8B-3ckbA:
undetectable		 1dm8A-3ckbA:
21.88
1dm8B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_B_H4BB2600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 1dm8A-3ckbA:
0.0
1dm8B-3ckbA:
undetectable		 1dm8A-3ckbA:
21.88
1dm8B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.04A 1dmiA-3ckbA:
undetectable
1dmiB-3ckbA:
undetectable		 1dmiA-3ckbA:
21.88
1dmiB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 1dmiA-3ckbA:
undetectable
1dmiB-3ckbA:
undetectable		 1dmiA-3ckbA:
21.88
1dmiB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_A_H4BA1600_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 1fopA-3ckbA:
undetectable
1fopB-3ckbA:
undetectable		 1fopA-3ckbA:
21.88
1fopB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_B_H4BB2600_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 1fopA-3ckbA:
undetectable
1fopB-3ckbA:
undetectable		 1fopA-3ckbA:
21.88
1fopB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.07A 1k2rA-3ckbA:
undetectable
1k2rB-3ckbA:
undetectable		 1k2rA-3ckbA:
19.68
1k2rB-3ckbA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.03A 1k2uA-3ckbA:
undetectable
1k2uB-3ckbA:
undetectable		 1k2uA-3ckbA:
19.68
1k2uB-3ckbA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 494
ASP A 498
TYR A 237
TRP A 164
 None
 1.42A 1kf6M-3ckbA:
2.5
1kf6N-3ckbA:
undetectable		 1kf6M-3ckbA:
20.62
1kf6N-3ckbA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.05A 1lzzA-3ckbA:
undetectable
1lzzB-3ckbA:
undetectable		 1lzzA-3ckbA:
19.68
1lzzB-3ckbA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.06A 1mmwA-3ckbA:
undetectable
1mmwB-3ckbA:
2.8		 1mmwA-3ckbA:
19.68
1mmwB-3ckbA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 458
ILE A 460
ALA A 250
ILE A 254
 None
 0.71A 1n49A-3ckbA:
undetectable		 1n49A-3ckbA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 1nseA-3ckbA:
0.0
1nseB-3ckbA:
undetectable		 1nseA-3ckbA:
21.88
1nseB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.96A 1nseA-3ckbA:
0.0
1nseB-3ckbA:
undetectable		 1nseA-3ckbA:
21.88
1nseB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 1nsiA-3ckbA:
undetectable
1nsiB-3ckbA:
undetectable		 1nsiA-3ckbA:
21.74
1nsiB-3ckbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.03A 1nsiA-3ckbA:
undetectable
1nsiB-3ckbA:
undetectable		 1nsiA-3ckbA:
21.74
1nsiB-3ckbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.06A 1p6lA-3ckbA:
undetectable
1p6lB-3ckbA:
undetectable		 1p6lA-3ckbA:
21.33
1p6lB-3ckbA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 1p6lA-3ckbA:
0.0
1p6lB-3ckbA:
0.0		 1p6lA-3ckbA:
21.33
1p6lB-3ckbA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 1p6mA-3ckbA:
undetectable
1p6mB-3ckbA:
undetectable		 1p6mA-3ckbA:
21.33
1p6mB-3ckbA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.02A 1p6mA-3ckbA:
undetectable
1p6mB-3ckbA:
undetectable		 1p6mA-3ckbA:
21.33
1p6mB-3ckbA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 1p6nA-3ckbA:
undetectable
1p6nB-3ckbA:
2.9		 1p6nA-3ckbA:
21.33
1p6nB-3ckbA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.02A 1p6nA-3ckbA:
undetectable
1p6nB-3ckbA:
2.9		 1p6nA-3ckbA:
21.33
1p6nB-3ckbA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 1q2oA-3ckbA:
0.0
1q2oB-3ckbA:
2.9		 1q2oA-3ckbA:
21.34
1q2oB-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 1q2oA-3ckbA:
undetectable
1q2oB-3ckbA:
2.9		 1q2oA-3ckbA:
21.34
1q2oB-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 1rs8A-3ckbA:
undetectable
1rs8B-3ckbA:
2.9		 1rs8A-3ckbA:
21.34
1rs8B-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.04A 1rs8A-3ckbA:
0.0
1rs8B-3ckbA:
2.9		 1rs8A-3ckbA:
21.34
1rs8B-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.05A 1rs9A-3ckbA:
3.0
1rs9B-3ckbA:
undetectable		 1rs9A-3ckbA:
21.34
1rs9B-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.03A 1rs9A-3ckbA:
3.0
1rs9B-3ckbA:
0.0		 1rs9A-3ckbA:
21.34
1rs9B-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 456
LEU A 443
ILE A 482
ARG A 495
ARG A 501
 None
 1.16A 1rx3A-3ckbA:
undetectable		 1rx3A-3ckbA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		5 / 10 GLU A 281
LEU A 267
ARG A 382
PHE A 489
ALA A 439
 None
 1.08A 1wygA-3ckbA:
undetectable		 1wygA-3ckbA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.07A 1zvlA-3ckbA:
undetectable
1zvlB-3ckbA:
2.3		 1zvlA-3ckbA:
19.49
1zvlB-3ckbA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.02A 1zvlA-3ckbA:
undetectable
1zvlB-3ckbA:
2.3		 1zvlA-3ckbA:
19.49
1zvlB-3ckbA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 1zzsA-3ckbA:
3.0
1zzsB-3ckbA:
undetectable		 1zzsA-3ckbA:
21.34
1zzsB-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.96A 1zzsA-3ckbA:
3.0
1zzsB-3ckbA:
undetectable		 1zzsA-3ckbA:
21.34
1zzsB-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZT_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.93A 1zztA-3ckbA:
0.0
1zztB-3ckbA:
0.0		 1zztA-3ckbA:
21.09
1zztB-3ckbA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZT_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 1zztA-3ckbA:
0.0
1zztB-3ckbA:
0.0		 1zztA-3ckbA:
21.09
1zztB-3ckbA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.04A 2g6kA-3ckbA:
undetectable
2g6kB-3ckbA:
undetectable		 2g6kA-3ckbA:
19.31
2g6kB-3ckbA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 2hx2A-3ckbA:
undetectable
2hx2B-3ckbA:
undetectable		 2hx2A-3ckbA:
21.34
2hx2B-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 2hx2A-3ckbA:
undetectable
2hx2B-3ckbA:
undetectable		 2hx2A-3ckbA:
21.34
2hx2B-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 294
VAL A 303
THR A 316
 None
 0.76A 2nmzA-3ckbA:
undetectable		 2nmzA-3ckbA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 294
VAL A 303
THR A 316
 None
 0.75A 2nnkA-3ckbA:
undetectable		 2nnkA-3ckbA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.02A 2nseA-3ckbA:
0.0
2nseB-3ckbA:
2.1		 2nseA-3ckbA:
21.88
2nseB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.04A 2nsiA-3ckbA:
undetectable
2nsiB-3ckbA:
undetectable		 2nsiA-3ckbA:
21.74
2nsiB-3ckbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.04A 2nsiA-3ckbA:
undetectable
2nsiB-3ckbA:
undetectable		 2nsiA-3ckbA:
21.74
2nsiB-3ckbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 2nsiC-3ckbA:
undetectable
2nsiD-3ckbA:
undetectable		 2nsiC-3ckbA:
21.74
2nsiD-3ckbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 213
TYR A 258
PRO A 285
LEU A 225
ASP A 219
 None
 1.13A 2nv4A-3ckbA:
undetectable		 2nv4A-3ckbA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.04A 3b3mA-3ckbA:
0.0
3b3mB-3ckbA:
undetectable		 3b3mA-3ckbA:
19.13
3b3mB-3ckbA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.06A 3b3oA-3ckbA:
undetectable
3b3oB-3ckbA:
undetectable		 3b3oA-3ckbA:
19.13
3b3oB-3ckbA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 3dqsA-3ckbA:
3.0
3dqsB-3ckbA:
undetectable		 3dqsA-3ckbA:
21.34
3dqsB-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 3dqsA-3ckbA:
0.0
3dqsB-3ckbA:
0.0		 3dqsA-3ckbA:
21.34
3dqsB-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.05A 3dqtA-3ckbA:
0.0
3dqtB-3ckbA:
0.0		 3dqtA-3ckbA:
21.34
3dqtB-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.06A 3dqtA-3ckbA:
undetectable
3dqtB-3ckbA:
2.9		 3dqtA-3ckbA:
21.34
3dqtB-3ckbA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 3e7gA-3ckbA:
undetectable
3e7gB-3ckbA:
undetectable		 3e7gA-3ckbA:
20.93
3e7gB-3ckbA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3e7gA-3ckbA:
undetectable
3e7gB-3ckbA:
undetectable		 3e7gA-3ckbA:
20.93
3e7gB-3ckbA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 3e7gC-3ckbA:
undetectable
3e7gD-3ckbA:
undetectable		 3e7gC-3ckbA:
20.93
3e7gD-3ckbA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 8 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3e7gC-3ckbA:
undetectable
3e7gD-3ckbA:
undetectable		 3e7gC-3ckbA:
20.93
3e7gD-3ckbA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TYR A 386
ILE A 369
GLY A 390
ARG A 313
 None
 0.84A 3elzA-3ckbA:
undetectable		 3elzA-3ckbA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		5 / 11 ALA A 439
ASN A 272
LEU A 267
GLU A 488
ASN A 277
 None
 1.23A 3jw5A-3ckbA:
undetectable		 3jw5A-3ckbA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 3jwxA-3ckbA:
undetectable
3jwxB-3ckbA:
3.0		 3jwxA-3ckbA:
21.88
3jwxB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.03A 3jwyA-3ckbA:
undetectable
3jwyB-3ckbA:
3.0		 3jwyA-3ckbA:
21.88
3jwyB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.05A 3jwzA-3ckbA:
3.0
3jwzB-3ckbA:
undetectable		 3jwzA-3ckbA:
21.88
3jwzB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3jwzA-3ckbA:
3.0
3jwzB-3ckbA:
undetectable		 3jwzA-3ckbA:
21.88
3jwzB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.07A 3jx0A-3ckbA:
undetectable
3jx0B-3ckbA:
undetectable		 3jx0A-3ckbA:
19.31
3jx0B-3ckbA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 8 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.05A 3jx1A-3ckbA:
undetectable
3jx1B-3ckbA:
undetectable		 3jx1A-3ckbA:
19.31
3jx1B-3ckbA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 294
VAL A 303
THR A 316
 None
 0.78A 3k4vA-3ckbA:
undetectable		 3k4vA-3ckbA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 294
VAL A 303
THR A 316
 None
 0.84A 3k4vD-3ckbA:
undetectable		 3k4vD-3ckbA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 3n5rA-3ckbA:
undetectable
3n5rB-3ckbA:
undetectable		 3n5rA-3ckbA:
21.88
3n5rB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3n5rA-3ckbA:
undetectable
3n5rB-3ckbA:
undetectable		 3n5rA-3ckbA:
21.88
3n5rB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.03A 3n5sA-3ckbA:
3.0
3n5sB-3ckbA:
3.0		 3n5sA-3ckbA:
21.88
3n5sB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.04A 3n5sA-3ckbA:
3.0
3n5sB-3ckbA:
3.0		 3n5sA-3ckbA:
21.88
3n5sB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 3n5tA-3ckbA:
undetectable
3n5tB-3ckbA:
undetectable		 3n5tA-3ckbA:
21.88
3n5tB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 3n5tA-3ckbA:
undetectable
3n5tB-3ckbA:
undetectable		 3n5tA-3ckbA:
21.88
3n5tB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.05A 3n67A-3ckbA:
0.0
3n67B-3ckbA:
0.0		 3n67A-3ckbA:
21.64
3n67B-3ckbA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 3n67A-3ckbA:
0.0
3n67B-3ckbA:
0.0		 3n67A-3ckbA:
21.64
3n67B-3ckbA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N68_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 3n68A-3ckbA:
0.0
3n68B-3ckbA:
2.9		 3n68A-3ckbA:
21.64
3n68B-3ckbA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N69_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 3n69A-3ckbA:
0.0
3n69B-3ckbA:
0.0		 3n69A-3ckbA:
21.64
3n69B-3ckbA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 3n6aA-3ckbA:
0.0
3n6aB-3ckbA:
0.0		 3n6aA-3ckbA:
21.64
3n6aB-3ckbA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3n6aA-3ckbA:
0.0
3n6aB-3ckbA:
0.0		 3n6aA-3ckbA:
21.64
3n6aB-3ckbA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 3n6eA-3ckbA:
0.0
3n6eB-3ckbA:
undetectable		 3n6eA-3ckbA:
21.88
3n6eB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 3n6fA-3ckbA:
undetectable
3n6fB-3ckbA:
3.0		 3n6fA-3ckbA:
21.88
3n6fB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 3n6gA-3ckbA:
undetectable
3n6gB-3ckbA:
undetectable		 3n6gA-3ckbA:
21.88
3n6gB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 294
VAL A 303
THR A 316
 None
 0.84A 3nduD-3ckbA:
undetectable		 3nduD-3ckbA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3nleA-3ckbA:
0.0
3nleB-3ckbA:
0.0		 3nleA-3ckbA:
21.88
3nleB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 3nlgA-3ckbA:
undetectable
3nlgB-3ckbA:
2.9		 3nlgA-3ckbA:
21.88
3nlgB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3nlgA-3ckbA:
undetectable
3nlgB-3ckbA:
2.9		 3nlgA-3ckbA:
21.88
3nlgB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 3nlhA-3ckbA:
undetectable
3nlhB-3ckbA:
3.0		 3nlhA-3ckbA:
21.88
3nlhB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 3nlhA-3ckbA:
0.0
3nlhB-3ckbA:
0.0		 3nlhA-3ckbA:
21.88
3nlhB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3nltA-3ckbA:
0.0
3nltB-3ckbA:
0.0		 3nltA-3ckbA:
21.88
3nltB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 3nluA-3ckbA:
0.0
3nluB-3ckbA:
0.0		 3nluA-3ckbA:
21.88
3nluB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 3nosA-3ckbA:
3.4
3nosB-3ckbA:
3.4		 3nosA-3ckbA:
21.76
3nosB-3ckbA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 3nosA-3ckbA:
3.4
3nosB-3ckbA:
3.4		 3nosA-3ckbA:
21.76
3nosB-3ckbA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 283
PHE A 157
ALA A 218
ASN A 223
 None
 0.88A 3pgyA-3ckbA:
undetectable
3pgyB-3ckbA:
undetectable		 3pgyA-3ckbA:
20.96
3pgyB-3ckbA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 294
VAL A 303
THR A 316
 None
 0.72A 3pwrA-3ckbA:
undetectable		 3pwrA-3ckbA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 3rqoA-3ckbA:
0.0
3rqoB-3ckbA:
0.0		 3rqoA-3ckbA:
21.88
3rqoB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 3rqpA-3ckbA:
0.0
3rqpB-3ckbA:
0.0		 3rqpA-3ckbA:
21.88
3rqpB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 294
VAL A 303
THR A 316
 None
 0.79A 3tl9A-3ckbA:
undetectable		 3tl9A-3ckbA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 435
GLY A 216
ILE A 286
ILE A 282
LEU A 158
 None
 1.22A 3uj7B-3ckbA:
undetectable		 3uj7B-3ckbA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 471
ARG A 382
ASP A 483
 None
 0.95A 3wipG-3ckbA:
undetectable
3wipH-3ckbA:
undetectable		 3wipG-3ckbA:
19.18
3wipH-3ckbA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 4c3aA-3ckbA:
undetectable
4c3aB-3ckbA:
undetectable		 4c3aA-3ckbA:
21.88
4c3aB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 4c3aA-3ckbA:
undetectable
4c3aB-3ckbA:
undetectable		 4c3aA-3ckbA:
21.88
4c3aB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4carA-3ckbA:
0.0
4carB-3ckbA:
0.0		 4carA-3ckbA:
21.88
4carB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 4carA-3ckbA:
0.0
4carB-3ckbA:
0.0		 4carA-3ckbA:
21.88
4carB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.97A 4cftA-3ckbA:
undetectable
4cftB-3ckbA:
undetectable		 4cftA-3ckbA:
21.88
4cftB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 4cftA-3ckbA:
undetectable
4cftB-3ckbA:
undetectable		 4cftA-3ckbA:
21.88
4cftB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 4ctyA-3ckbA:
undetectable
4ctyB-3ckbA:
3.0		 4ctyA-3ckbA:
21.88
4ctyB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 4cu0A-3ckbA:
2.9
4cu0B-3ckbA:
2.5		 4cu0A-3ckbA:
21.88
4cu0B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 4cu0A-3ckbA:
2.9
4cu0B-3ckbA:
2.5		 4cu0A-3ckbA:
21.88
4cu0B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 4cu1A-3ckbA:
3.1
4cu1B-3ckbA:
undetectable		 4cu1A-3ckbA:
21.88
4cu1B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.95A 4cu1A-3ckbA:
3.1
4cu1B-3ckbA:
undetectable		 4cu1A-3ckbA:
21.88
4cu1B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 4cwvA-3ckbA:
undetectable
4cwvB-3ckbA:
2.9		 4cwvA-3ckbA:
21.88
4cwvB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.95A 4cwvA-3ckbA:
undetectable
4cwvB-3ckbA:
2.9		 4cwvA-3ckbA:
21.88
4cwvB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4cwwA-3ckbA:
undetectable
4cwwB-3ckbA:
undetectable		 4cwwA-3ckbA:
21.88
4cwwB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 4cwwA-3ckbA:
undetectable
4cwwB-3ckbA:
undetectable		 4cwwA-3ckbA:
21.88
4cwwB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4cwxA-3ckbA:
undetectable
4cwxB-3ckbA:
2.9		 4cwxA-3ckbA:
21.88
4cwxB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 4cwxA-3ckbA:
undetectable
4cwxB-3ckbA:
2.9		 4cwxA-3ckbA:
21.88
4cwxB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 4cwyA-3ckbA:
3.2
4cwyB-3ckbA:
3.0		 4cwyA-3ckbA:
21.88
4cwyB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 4cwyA-3ckbA:
3.2
4cwyB-3ckbA:
3.0		 4cwyA-3ckbA:
21.88
4cwyB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 4cwzA-3ckbA:
undetectable
4cwzB-3ckbA:
undetectable		 4cwzA-3ckbA:
21.70
4cwzB-3ckbA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 4cwzA-3ckbA:
undetectable
4cwzB-3ckbA:
undetectable		 4cwzA-3ckbA:
21.70
4cwzB-3ckbA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4cx0A-3ckbA:
undetectable
4cx0B-3ckbA:
2.9		 4cx0A-3ckbA:
21.70
4cx0B-3ckbA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 4cx0A-3ckbA:
0.0
4cx0B-3ckbA:
0.0		 4cx0A-3ckbA:
21.70
4cx0B-3ckbA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 4cx7A-3ckbA:
undetectable
4cx7B-3ckbA:
undetectable		 4cx7A-3ckbA:
21.74
4cx7B-3ckbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 4cx7C-3ckbA:
0.0
4cx7D-3ckbA:
1.1		 4cx7C-3ckbA:
21.74
4cx7D-3ckbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_A_H4BA1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.96A 4d1oA-3ckbA:
undetectable
4d1oB-3ckbA:
undetectable		 4d1oA-3ckbA:
20.99
4d1oB-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 4d1oA-3ckbA:
undetectable
4d1oB-3ckbA:
undetectable		 4d1oA-3ckbA:
20.99
4d1oB-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 4d1pA-3ckbA:
0.0
4d1pB-3ckbA:
0.0		 4d1pA-3ckbA:
20.99
4d1pB-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 4d1pA-3ckbA:
undetectable
4d1pB-3ckbA:
2.9		 4d1pA-3ckbA:
20.99
4d1pB-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.96A 4d33A-3ckbA:
undetectable
4d33B-3ckbA:
undetectable		 4d33A-3ckbA:
21.88
4d33B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.95A 4d33A-3ckbA:
undetectable
4d33B-3ckbA:
undetectable		 4d33A-3ckbA:
21.88
4d33B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 4d34A-3ckbA:
0.0
4d34B-3ckbA:
0.0		 4d34A-3ckbA:
21.88
4d34B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 4d34A-3ckbA:
0.0
4d34B-3ckbA:
0.0		 4d34A-3ckbA:
21.88
4d34B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.96A 4d35A-3ckbA:
undetectable
4d35B-3ckbA:
undetectable		 4d35A-3ckbA:
21.88
4d35B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.93A 4d35A-3ckbA:
0.0
4d35B-3ckbA:
0.0		 4d35A-3ckbA:
21.88
4d35B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4d36A-3ckbA:
2.5
4d36B-3ckbA:
2.6		 4d36A-3ckbA:
21.88
4d36B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 4d36A-3ckbA:
0.0
4d36B-3ckbA:
0.0		 4d36A-3ckbA:
21.88
4d36B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.94A 4d37A-3ckbA:
undetectable
4d37B-3ckbA:
0.0		 4d37A-3ckbA:
21.88
4d37B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 4d37A-3ckbA:
0.0
4d37B-3ckbA:
0.0		 4d37A-3ckbA:
21.88
4d37B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.96A 4d38A-3ckbA:
undetectable
4d38B-3ckbA:
undetectable		 4d38A-3ckbA:
21.88
4d38B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 4d38A-3ckbA:
undetectable
4d38B-3ckbA:
undetectable		 4d38A-3ckbA:
21.88
4d38B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.96A 4d39A-3ckbA:
2.4
4d39B-3ckbA:
undetectable		 4d39A-3ckbA:
21.88
4d39B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 4d39A-3ckbA:
2.4
4d39B-3ckbA:
undetectable		 4d39A-3ckbA:
21.88
4d39B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 4d3aA-3ckbA:
undetectable
4d3aB-3ckbA:
undetectable		 4d3aA-3ckbA:
21.88
4d3aB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.96A 4d3aA-3ckbA:
0.0
4d3aB-3ckbA:
0.0		 4d3aA-3ckbA:
21.88
4d3aB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.03A 4d3bA-3ckbA:
2.9
4d3bB-3ckbA:
undetectable		 4d3bA-3ckbA:
19.13
4d3bB-3ckbA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.03A 4fvzA-3ckbA:
2.5
4fvzB-3ckbA:
undetectable		 4fvzA-3ckbA:
19.13
4fvzB-3ckbA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 159
GLU A 177
ASN A 134
 None
 0.88A 4imaD-3ckbA:
undetectable		 4imaD-3ckbA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4imxA-3ckbA:
undetectable
4imxB-3ckbA:
undetectable		 4imxA-3ckbA:
21.88
4imxB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 159
GLU A 177
ASN A 134
 None
 0.83A 4ip7D-3ckbA:
undetectable		 4ip7D-3ckbA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.97A 4jskA-3ckbA:
0.0
4jskB-3ckbA:
0.0		 4jskA-3ckbA:
21.88
4jskB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 4jsmA-3ckbA:
2.4
4jsmB-3ckbA:
undetectable		 4jsmA-3ckbA:
21.88
4jsmB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 4jsmA-3ckbA:
2.4
4jsmB-3ckbA:
undetectable		 4jsmA-3ckbA:
21.88
4jsmB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 4k5hA-3ckbA:
undetectable
4k5hB-3ckbA:
3.0		 4k5hA-3ckbA:
21.88
4k5hB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 4k5hA-3ckbA:
undetectable
4k5hB-3ckbA:
3.0		 4k5hA-3ckbA:
21.88
4k5hB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4k5iA-3ckbA:
undetectable
4k5iB-3ckbA:
undetectable		 4k5iA-3ckbA:
21.88
4k5iB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.94A 4k5iA-3ckbA:
undetectable
4k5iB-3ckbA:
undetectable		 4k5iA-3ckbA:
21.88
4k5iB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.97A 4k5jA-3ckbA:
0.0
4k5jB-3ckbA:
undetectable		 4k5jA-3ckbA:
21.88
4k5jB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.96A 4k5jA-3ckbA:
undetectable
4k5jB-3ckbA:
undetectable		 4k5jA-3ckbA:
21.88
4k5jB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4k5kA-3ckbA:
3.1
4k5kB-3ckbA:
undetectable		 4k5kA-3ckbA:
21.88
4k5kB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 4k5kA-3ckbA:
3.1
4k5kB-3ckbA:
undetectable		 4k5kA-3ckbA:
21.88
4k5kB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 4kcpA-3ckbA:
undetectable
4kcpB-3ckbA:
3.0		 4kcpA-3ckbA:
21.88
4kcpB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 4kcqA-3ckbA:
3.0
4kcqB-3ckbA:
undetectable		 4kcqA-3ckbA:
21.88
4kcqB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 4kcqA-3ckbA:
3.0
4kcqB-3ckbA:
undetectable		 4kcqA-3ckbA:
21.88
4kcqB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 4kcrA-3ckbA:
2.4
4kcrB-3ckbA:
undetectable		 4kcrA-3ckbA:
21.88
4kcrB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 4kcrA-3ckbA:
2.4
4kcrB-3ckbA:
undetectable		 4kcrA-3ckbA:
21.88
4kcrB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 4kcsA-3ckbA:
2.4
4kcsB-3ckbA:
undetectable		 4kcsA-3ckbA:
21.88
4kcsB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 4kcsA-3ckbA:
0.0
4kcsB-3ckbA:
0.0		 4kcsA-3ckbA:
21.88
4kcsB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 4luwA-3ckbA:
undetectable
4luwB-3ckbA:
undetectable		 4luwA-3ckbA:
21.88
4luwB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.91A 4nosA-3ckbA:
undetectable
4nosB-3ckbA:
undetectable		 4nosA-3ckbA:
20.21
4nosB-3ckbA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.95A 4nosC-3ckbA:
undetectable
4nosD-3ckbA:
undetectable		 4nosC-3ckbA:
20.21
4nosD-3ckbA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 4nosC-3ckbA:
undetectable
4nosD-3ckbA:
undetectable		 4nosC-3ckbA:
20.21
4nosD-3ckbA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 4uchA-3ckbA:
undetectable
4uchB-3ckbA:
undetectable		 4uchA-3ckbA:
19.29
4uchB-3ckbA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.08A 4uh3A-3ckbA:
undetectable
4uh3B-3ckbA:
undetectable		 4uh3A-3ckbA:
19.13
4uh3B-3ckbA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.05A 4uh6A-3ckbA:
undetectable
4uh6B-3ckbA:
2.0		 4uh6A-3ckbA:
19.65
4uh6B-3ckbA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 4uh7A-3ckbA:
undetectable
4uh7B-3ckbA:
undetectable		 4uh7A-3ckbA:
21.88
4uh7B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.94A 4uh8A-3ckbA:
undetectable
4uh8B-3ckbA:
undetectable		 4uh8A-3ckbA:
21.88
4uh8B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 4uh8A-3ckbA:
undetectable
4uh8B-3ckbA:
undetectable		 4uh8A-3ckbA:
21.88
4uh8B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 4uh9A-3ckbA:
3.0
4uh9B-3ckbA:
undetectable		 4uh9A-3ckbA:
21.88
4uh9B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 4uh9A-3ckbA:
3.0
4uh9B-3ckbA:
undetectable		 4uh9A-3ckbA:
21.88
4uh9B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 4uhaA-3ckbA:
undetectable
4uhaB-3ckbA:
0.0		 4uhaA-3ckbA:
21.88
4uhaB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 4uhaA-3ckbA:
undetectable
4uhaB-3ckbA:
0.0		 4uhaA-3ckbA:
21.88
4uhaB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.97A 4upqA-3ckbA:
undetectable
4upqB-3ckbA:
undetectable		 4upqA-3ckbA:
21.88
4upqB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 4upqA-3ckbA:
undetectable
4upqB-3ckbA:
undetectable		 4upqA-3ckbA:
21.88
4upqB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 4uprA-3ckbA:
undetectable
4uprB-3ckbA:
3.0		 4uprA-3ckbA:
21.88
4uprB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 4upsA-3ckbA:
undetectable
4upsB-3ckbA:
3.0		 4upsA-3ckbA:
21.88
4upsB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 4upsA-3ckbA:
undetectable
4upsB-3ckbA:
3.0		 4upsA-3ckbA:
21.88
4upsB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 4uptA-3ckbA:
undetectable
4uptB-3ckbA:
undetectable		 4uptA-3ckbA:
21.88
4uptB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 4v3uC-3ckbA:
2.6
4v3uD-3ckbA:
undetectable		 4v3uC-3ckbA:
19.46
4v3uD-3ckbA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.96A 5adjA-3ckbA:
undetectable
5adjB-3ckbA:
undetectable		 5adjA-3ckbA:
21.88
5adjB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.95A 5adjA-3ckbA:
undetectable
5adjB-3ckbA:
undetectable		 5adjA-3ckbA:
21.88
5adjB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 5adkA-3ckbA:
undetectable
5adkB-3ckbA:
undetectable		 5adkA-3ckbA:
21.88
5adkB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 5adkA-3ckbA:
undetectable
5adkB-3ckbA:
undetectable		 5adkA-3ckbA:
21.88
5adkB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.94A 5adlA-3ckbA:
undetectable
5adlB-3ckbA:
2.5		 5adlA-3ckbA:
21.88
5adlB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.97A 5admA-3ckbA:
undetectable
5admB-3ckbA:
2.9		 5admA-3ckbA:
21.88
5admB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 5admA-3ckbA:
undetectable
5admB-3ckbA:
2.9		 5admA-3ckbA:
21.88
5admB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 5adnA-3ckbA:
undetectable
5adnB-3ckbA:
undetectable		 5adnA-3ckbA:
21.88
5adnB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 5adnA-3ckbA:
undetectable
5adnB-3ckbA:
undetectable		 5adnA-3ckbA:
21.88
5adnB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A 233
SER A 497
ARG A 494
 None
 0.82A 5b2qA-3ckbA:
undetectable		 5b2qA-3ckbA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 284
GLU A 440
LEU A 225
LEU A 226
ARG A 229
 None
 1.39A 5dxgA-3ckbA:
0.0		 5dxgA-3ckbA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 5fj2A-3ckbA:
undetectable
5fj2B-3ckbA:
undetectable		 5fj2A-3ckbA:
21.88
5fj2B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 5fj2A-3ckbA:
undetectable
5fj2B-3ckbA:
undetectable		 5fj2A-3ckbA:
21.88
5fj2B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 5fj3A-3ckbA:
undetectable
5fj3B-3ckbA:
2.9		 5fj3A-3ckbA:
21.88
5fj3B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.02A 5fj3A-3ckbA:
undetectable
5fj3B-3ckbA:
2.9		 5fj3A-3ckbA:
21.88
5fj3B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 5fvvA-3ckbA:
undetectable
5fvvB-3ckbA:
2.5		 5fvvA-3ckbA:
19.65
5fvvB-3ckbA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 5fvxA-3ckbA:
undetectable
5fvxB-3ckbA:
2.9		 5fvxA-3ckbA:
19.65
5fvxB-3ckbA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 5fvyA-3ckbA:
undetectable
5fvyB-3ckbA:
undetectable		 5fvyA-3ckbA:
21.88
5fvyB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 5fvyA-3ckbA:
undetectable
5fvyB-3ckbA:
undetectable		 5fvyA-3ckbA:
21.88
5fvyB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 5fvzA-3ckbA:
undetectable
5fvzB-3ckbA:
3.0		 5fvzA-3ckbA:
21.88
5fvzB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 440
GLU A 488
GLU A 492
PHE A 489
 None
 1.40A 5onlA-3ckbA:
undetectable		 5onlA-3ckbA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
GLU A 492
LEU A 225
ARG A 229
 None
 0.96A 5umwB-3ckbA:
undetectable
5umwE-3ckbA:
undetectable		 5umwB-3ckbA:
8.93
5umwE-3ckbA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 5uo8A-3ckbA:
0.0
5uo8B-3ckbA:
0.0		 5uo8A-3ckbA:
20.99
5uo8B-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 5uo8C-3ckbA:
0.0
5uo8D-3ckbA:
0.0		 5uo8C-3ckbA:
20.99
5uo8D-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 5uo8C-3ckbA:
0.0
5uo8D-3ckbA:
0.0		 5uo8C-3ckbA:
20.99
5uo8D-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.05A 5uo9A-3ckbA:
0.0
5uo9B-3ckbA:
0.0		 5uo9A-3ckbA:
20.99
5uo9B-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.94A 5uo9A-3ckbA:
undetectable
5uo9B-3ckbA:
0.0		 5uo9A-3ckbA:
20.99
5uo9B-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.95A 5uo9C-3ckbA:
0.0
5uo9D-3ckbA:
0.0		 5uo9C-3ckbA:
20.99
5uo9D-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.03A 5uodA-3ckbA:
undetectable
5uodB-3ckbA:
undetectable		 5uodA-3ckbA:
21.88
5uodB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 5uodA-3ckbA:
undetectable
5uodB-3ckbA:
undetectable		 5uodA-3ckbA:
21.88
5uodB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 5vuyA-3ckbA:
2.8
5vuyB-3ckbA:
undetectable		 5vuyA-3ckbA:
19.65
5vuyB-3ckbA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.03A 5vv6A-3ckbA:
undetectable
5vv6B-3ckbA:
undetectable		 5vv6A-3ckbA:
21.88
5vv6B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 5vv6A-3ckbA:
1.9
5vv6B-3ckbA:
0.0		 5vv6A-3ckbA:
21.88
5vv6B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 5vv7A-3ckbA:
undetectable
5vv7B-3ckbA:
3.0		 5vv7A-3ckbA:
21.88
5vv7B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 5vv7A-3ckbA:
undetectable
5vv7B-3ckbA:
3.0		 5vv7A-3ckbA:
21.88
5vv7B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.04A 5vv8A-3ckbA:
2.1
5vv8B-3ckbA:
0.0		 5vv8A-3ckbA:
21.88
5vv8B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.00A 5vv8A-3ckbA:
2.1
5vv8B-3ckbA:
0.0		 5vv8A-3ckbA:
21.88
5vv8B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.94A 5vv9A-3ckbA:
1.6
5vv9B-3ckbA:
0.0		 5vv9A-3ckbA:
21.88
5vv9B-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.94A 5vvaA-3ckbA:
undetectable
5vvaB-3ckbA:
undetectable		 5vvaA-3ckbA:
21.88
5vvaB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 5vvaA-3ckbA:
1.8
5vvaB-3ckbA:
0.0		 5vvaA-3ckbA:
21.88
5vvaB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 5vvbA-3ckbA:
0.0
5vvbB-3ckbA:
0.0		 5vvbA-3ckbA:
20.99
5vvbB-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.04A 5vvbA-3ckbA:
0.0
5vvbB-3ckbA:
0.0		 5vvbA-3ckbA:
20.99
5vvbB-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 5vvbC-3ckbA:
0.0
5vvbD-3ckbA:
0.0		 5vvbC-3ckbA:
20.99
5vvbD-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 5vvbC-3ckbA:
0.0
5vvbD-3ckbA:
0.0		 5vvbC-3ckbA:
20.99
5vvbD-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.05A 5vvcA-3ckbA:
undetectable
5vvcB-3ckbA:
0.0		 5vvcA-3ckbA:
20.99
5vvcB-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.03A 5vvcC-3ckbA:
0.0
5vvcD-3ckbA:
0.0		 5vvcC-3ckbA:
20.99
5vvcD-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 5vvdA-3ckbA:
0.0
5vvdB-3ckbA:
0.0		 5vvdA-3ckbA:
20.99
5vvdB-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 5vvdC-3ckbA:
undetectable
5vvdD-3ckbA:
0.0		 5vvdC-3ckbA:
20.99
5vvdD-3ckbA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.99A 5vvgA-3ckbA:
2.2
5vvgB-3ckbA:
0.0		 5vvgA-3ckbA:
21.88
5vvgB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.96A 5vvgA-3ckbA:
0.9
5vvgB-3ckbA:
0.0		 5vvgA-3ckbA:
21.88
5vvgB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 5vvnA-3ckbA:
undetectable
5vvnB-3ckbA:
0.0		 5vvnA-3ckbA:
21.88
5vvnB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.06A 5vvnA-3ckbA:
undetectable
5vvnB-3ckbA:
undetectable		 5vvnA-3ckbA:
21.88
5vvnB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A 466
PHE A 489
ARG A 437
 None
 0.98A 5y9yA-3ckbA:
undetectable		 5y9yA-3ckbA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 456
LEU A 443
ILE A 482
ARG A 495
ARG A 501
 None
 1.30A 5z6fA-3ckbA:
undetectable		 5z6fA-3ckbA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.07A 6autA-3ckbA:
undetectable
6autB-3ckbA:
undetectable		 6autA-3ckbA:
10.98
6autB-3ckbA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 6auyA-3ckbA:
undetectable
6auyB-3ckbA:
2.9		 6auyA-3ckbA:
11.78
6auyB-3ckbA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 6auzA-3ckbA:
undetectable
6auzB-3ckbA:
2.5		 6auzA-3ckbA:
11.78
6auzB-3ckbA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.03A 6av6A-3ckbA:
undetectable
6av6B-3ckbA:
undetectable		 6av6A-3ckbA:
11.08
6av6B-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.99A 6av6A-3ckbA:
undetectable
6av6B-3ckbA:
0.0		 6av6A-3ckbA:
11.08
6av6B-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.02A 6av7A-3ckbA:
undetectable
6av7B-3ckbA:
undetectable		 6av7A-3ckbA:
11.08
6av7B-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.98A 6av7A-3ckbA:
0.0
6av7B-3ckbA:
0.0		 6av7A-3ckbA:
11.08
6av7B-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.97A 6av7C-3ckbA:
undetectable
6av7D-3ckbA:
undetectable		 6av7C-3ckbA:
11.08
6av7D-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.02A 6av7C-3ckbA:
0.0
6av7D-3ckbA:
0.0		 6av7C-3ckbA:
11.08
6av7D-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 6cieA-3ckbA:
0.0
6cieB-3ckbA:
0.0		 6cieA-3ckbA:
11.08
6cieB-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.94A 6cieA-3ckbA:
undetectable
6cieB-3ckbA:
0.0		 6cieA-3ckbA:
11.08
6cieB-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.98A 6cieC-3ckbA:
0.0
6cieD-3ckbA:
0.0		 6cieC-3ckbA:
11.08
6cieD-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.02A 6cieC-3ckbA:
0.0
6cieD-3ckbA:
0.0		 6cieC-3ckbA:
11.08
6cieD-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.94A 6cifA-3ckbA:
0.0
6cifB-3ckbA:
0.0		 6cifA-3ckbA:
11.08
6cifB-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 6cifA-3ckbA:
undetectable
6cifB-3ckbA:
undetectable		 6cifA-3ckbA:
11.08
6cifB-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 0.95A 6cifC-3ckbA:
undetectable
6cifD-3ckbA:
undetectable		 6cifC-3ckbA:
11.08
6cifD-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.97A 6cifC-3ckbA:
0.0
6cifD-3ckbA:
0.0		 6cifC-3ckbA:
11.08
6cifD-3ckbA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 373
ASP A 381
ASN A 277
 None
 0.86A 6gngB-3ckbA:
undetectable		 6gngB-3ckbA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 440
GLU A 488
GLU A 492
PHE A 489
 None
 1.40A 6hrjA-3ckbA:
undetectable		 6hrjA-3ckbA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		5 / 11 ILE A 155
ALA A 218
LEU A  55
GLY A 216
PHE A  48
 None
 1.13A 6ieyA-3ckbA:
undetectable
6ieyB-3ckbA:
undetectable		 6ieyA-3ckbA:
19.48
6ieyB-3ckbA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.01A 8nseA-3ckbA:
0.0
8nseB-3ckbA:
undetectable		 8nseA-3ckbA:
21.88
8nseB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 1.01A 8nseA-3ckbA:
0.0
8nseB-3ckbA:
undetectable		 8nseA-3ckbA:
21.88
8nseB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 437
TRP A 485
PHE A 489
GLU A 484
 None
 1.00A 9nseA-3ckbA:
0.0
9nseB-3ckbA:
1.9		 9nseA-3ckbA:
21.88
9nseB-3ckbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3ckb SUSD
(Bacteroides
thetaiotaomicron) 		4 / 6 TRP A 485
PHE A 489
GLU A 484
ARG A 437
 None
 0.96A 9nseA-3ckbA:
undetectable
9nseB-3ckbA:
undetectable		 9nseA-3ckbA:
21.88
9nseB-3ckbA:
21.88