SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ckl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		3 / 4 VAL A 138
TRP A 173
TRP A 265
 None
 1.30A 1gmkA-3cklA:
undetectable
1gmkB-3cklA:
undetectable		 1gmkA-3cklA:
5.33
1gmkB-3cklA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		3 / 4 VAL A 136
TRP A 265
TRP A 173
 None
 1.39A 1gmkC-3cklA:
undetectable
1gmkD-3cklA:
undetectable		 1gmkC-3cklA:
5.33
1gmkD-3cklA:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.17A 1jffB-3cklA:
undetectable		 1jffB-3cklA:
20.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		6 / 10 PHE A  24
PRO A  47
LYS A  48
LYS A 107
HIS A 109
MET A 146
 STL  A 501 (-4.5A)
STL  A 501 ( 4.5A)
A3P  A 601 (-2.7A)
A3P  A 601 ( 4.8A)
STL  A 501 (-3.8A)
None
 1.19A 2d06A-3cklA:
45.3		 2d06A-3cklA:
53.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		7 / 10 PHE A  24
PRO A  47
LYS A  48
LYS A 107
HIS A 109
PHE A 143
MET A 249
 STL  A 501 (-4.5A)
STL  A 501 ( 4.5A)
A3P  A 601 (-2.7A)
A3P  A 601 ( 4.8A)
STL  A 501 (-3.8A)
STL  A 501 (-4.6A)
None
 0.51A 2d06A-3cklA:
45.3		 2d06A-3cklA:
53.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 10 PHE A  24
PRO A  47
LYS A 107
HIS A 109
MET A 146
 STL  A 501 (-4.5A)
STL  A 501 ( 4.5A)
A3P  A 601 ( 4.8A)
STL  A 501 (-3.8A)
None
 1.04A 2d06B-3cklA:
45.3		 2d06B-3cklA:
53.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		7 / 10 PHE A  24
PRO A  47
LYS A 107
HIS A 109
PHE A 143
TYR A 241
MET A 249
 STL  A 501 (-4.5A)
STL  A 501 ( 4.5A)
A3P  A 601 ( 4.8A)
STL  A 501 (-3.8A)
STL  A 501 (-4.6A)
None
None
 0.54A 2d06B-3cklA:
45.3		 2d06B-3cklA:
53.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.17A 2hxfB-3cklA:
undetectable		 2hxfB-3cklA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.17A 2hxhB-3cklA:
undetectable		 2hxhB-3cklA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.17A 2p4nB-3cklA:
undetectable		 2p4nB-3cklA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.17A 2wbeB-3cklA:
undetectable		 2wbeB-3cklA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.17A 3dcoB-3cklA:
undetectable		 3dcoB-3cklA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.19A 3edlB-3cklA:
undetectable		 3edlB-3cklA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.15A 3iz0B-3cklA:
undetectable		 3iz0B-3cklA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		4 / 6 HIS A 243
GLU A  56
ASP A  66
GLU A  68
 None
 0.88A 3vywA-3cklA:
undetectable		 3vywA-3cklA:
23.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		4 / 9 LYS A 107
HIS A 109
PHE A 143
MET A 249
 A3P  A 601 ( 4.8A)
STL  A 501 (-3.8A)
STL  A 501 (-4.6A)
None
 0.33A 4jvlA-3cklA:
44.0		 4jvlA-3cklA:
55.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.13A 5hnwB-3cklA:
undetectable		 5hnwB-3cklA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		5 / 12 LEU A  62
PHE A 211
LEU A 212
ARG A 104
PRO A 188
 None
 1.16A 5hnyB-3cklA:
undetectable		 5hnyB-3cklA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 3ckl SULFOTRANSFERASE
FAMILY CYTOSOLIC 1B
MEMBER 1
(Homo
sapiens) 		4 / 8 GLY A  93
THR A  91
LEU A  97
ASN A 100
 None
 0.98A 5hwaA-3cklA:
undetectable		 5hwaA-3cklA:
20.70