SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3clj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 8 LEU A 108
GLY A  73
ILE A  72
VAL A 104
ILE A 105
 None
 1.08A 1d4yB-3cljA:
undetectable		 1d4yB-3cljA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 9 ILE A  51
VAL A 104
ILE A  98
ILE A  46
ILE A  50
 None
 0.92A 1hshB-3cljA:
undetectable		 1hshB-3cljA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 108
GLY A  73
ILE A  72
VAL A 104
ILE A 105
 None
 0.97A 2avoA-3cljA:
undetectable		 2avoA-3cljA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 112
ASP A 111
LEU A 108
LEU A  66
GLY A  23
 None
 0.82A 2jfaB-3cljA:
undetectable		 2jfaB-3cljA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 136
ILE A  72
THR A  33
ASP A  78
ILE A 130
 None
 0.96A 2jn3A-3cljA:
undetectable		 2jn3A-3cljA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 108
GLY A  73
ILE A  72
VAL A 104
ILE A 105
 None
 0.96A 2o4pB-3cljA:
undetectable		 2o4pB-3cljA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 8 SER A  60
SER A 116
GLY A  64
CYH A  57
GLY A  23
 None
 1.37A 2vinA-3cljA:
undetectable		 2vinA-3cljA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 133
GLU A 122
SER A 134
 None
 0.89A 2xkkA-3cljA:
undetectable
2xkkC-3cljA:
undetectable		 2xkkA-3cljA:
12.77
2xkkC-3cljA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 108
GLY A  73
ILE A  72
VAL A 104
ILE A 105
 None
 1.00A 3d1yB-3cljA:
undetectable		 3d1yB-3cljA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		6 / 12 ARG A  55
LEU A 108
GLY A  73
ILE A  72
VAL A 104
ILE A 105
 None
 1.08A 3ndtB-3cljA:
undetectable		 3ndtB-3cljA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		6 / 12 ARG A  55
LEU A 108
GLY A  73
ILE A  72
VAL A 104
ILE A 105
 None
 1.31A 3tl9B-3cljA:
undetectable		 3tl9B-3cljA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFX_A_ACTA404_0
(THIAMINE
BIOSYNTHESIS
LIPOPROTEIN APBE)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		4 / 5 SER A  54
ARG A  55
LEU A 108
ASP A 111
 None
 1.45A 4ifxA-3cljA:
undetectable		 4ifxA-3cljA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG1_A_ACTA504_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		4 / 5 SER A  54
ARG A  55
LEU A 108
ASP A 111
 None
 1.41A 4ig1A-3cljA:
undetectable		 4ig1A-3cljA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  66
SER A  54
LEU A 101
LEU A 127
LEU A 108
 None
 1.32A 4or0A-3cljA:
undetectable		 4or0A-3cljA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 112
ASP A 111
LEU A 108
LEU A  66
GLY A  23
 None
 0.77A 4xi3B-3cljA:
undetectable		 4xi3B-3cljA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 3clj PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 108
GLY A  73
ILE A  72
VAL A 104
ILE A 105
 None
 1.12A 5kr2D-3cljA:
undetectable		 5kr2D-3cljA:
19.50