SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3clq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 10 LEU A 229
ALA A 180
ASP A 153
ASP A 299
GLY A 177
 None
 1.20A 1d4sA-3clqA:
undetectable		 1d4sA-3clqA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 5 SER A 185
PHE A 278
VAL A 191
PHE A 194
 None
 1.30A 1oipA-3clqA:
undetectable		 1oipA-3clqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A 422
ALA A 294
VAL A 435
PRO A 419
ALA A 372
 None
 1.18A 1sg9C-3clqA:
undetectable		 1sg9C-3clqA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 4 GLY A 358
SER A 360
ILE A 436
HIS A 244
 None
 1.23A 1yajJ-3clqA:
undetectable		 1yajJ-3clqA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 SER A 163
GLY A 121
PHE A 125
VAL A 201
ALA A 118
 None
 1.21A 2avdB-3clqA:
undetectable		 2avdB-3clqA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 8 ARG A 339
PRO A 104
VAL A 318
GLY A 317
 None
 0.88A 2qd5B-3clqA:
undetectable		 2qd5B-3clqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 11 THR A 401
ILE A 422
GLY A 421
GLY A 367
PRO A 434
 None
 1.22A 2y7kA-3clqA:
undetectable		 2y7kA-3clqA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 10 THR A 401
ILE A 422
GLY A 421
GLY A 367
PRO A 434
 None
 1.28A 2y7pA-3clqA:
undetectable		 2y7pA-3clqA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		6 / 12 ILE A 227
ARG A 230
ASP A 228
ILE A 171
ALA A 293
TYR A 366
 None
 1.31A 3jb1A-3clqA:
undetectable		 3jb1A-3clqA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 THR A 365
GLY A 370
GLY A 369
ASN A 456
VAL A 435
 None
 1.03A 3nk7A-3clqA:
undetectable		 3nk7A-3clqA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 11 ILE A  74
ILE A  75
VAL A 408
SER A 394
GLY A 417
 None
 1.06A 4ac9B-3clqA:
undetectable
4ac9C-3clqA:
undetectable		 4ac9B-3clqA:
21.44
4ac9C-3clqA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 7 ALA A 159
ALA A 122
GLY A 121
ILE A  99
 None
 0.66A 4eatA-3clqA:
undetectable		 4eatA-3clqA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 8 ALA A 135
ASP A 134
ASP A 131
PRO A 445
 None
 0.86A 4eyrB-3clqA:
undetectable		 4eyrB-3clqA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 GLY A 317
ASP A 356
ILE A 440
ARG A 315
VAL A 161
 None
 1.00A 4q5mA-3clqA:
undetectable		 4q5mA-3clqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 9 ALA A 294
ASN A 437
ILE A 436
VAL A 435
GLY A 369
 None
 1.28A 4r20B-3clqA:
0.7		 4r20B-3clqA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 ASN A 173
SER A  77
ARG A  73
 None
 0.88A 5b2qA-3clqA:
0.0		 5b2qA-3clqA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 5 GLY A 250
GLU A 242
HIS A 244
ASP A 283
 None
 1.17A 5c0oH-3clqA:
undetectable		 5c0oH-3clqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		3 / 3 ASN A 437
ASP A 241
GLY A 240
 None
 0.61A 5fctB-3clqA:
undetectable		 5fctB-3clqA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 ASP A  85
LEU A 254
ALA A 219
GLN A 187
LEU A 212
 None
 1.35A 5syfB-3clqA:
undetectable		 5syfB-3clqA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 6 GLU A 389
TYR A 393
GLY A 370
GLY A 369
 None
 0.94A 5x7pB-3clqA:
undetectable		 5x7pB-3clqA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 VAL A 191
LEU A 216
MET A 208
THR A 289
GLY A 287
 None
 1.31A 6brdA-3clqA:
undetectable		 6brdA-3clqA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 5 PHE A 462
VAL A 340
MET A 313
VAL A 461
 None
 1.32A 6ekzA-3clqA:
undetectable		 6ekzA-3clqA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 3clq UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		4 / 7 GLY A 160
GLY A 287
TYR A 284
ASN A 183
 None
 0.82A 6nm4A-3clqA:
undetectable		 6nm4A-3clqA:
18.47