SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3clv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3clv RAB5 PROTEIN,
PUTATIVE
(Plasmodium
falciparum) 		5 / 10 ILE A  97
THR A  10
VAL A  24
ILE A  23
ILE A 194
 None
 1.31A 3kpbD-3clvA:
undetectable		 3kpbD-3clvA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 3clv RAB5 PROTEIN,
PUTATIVE
(Plasmodium
falciparum) 		4 / 5 THR A 100
GLY A  14
VAL A 123
TYR A 114
 None
 1.13A 4grkA-3clvA:
undetectable		 4grkA-3clvA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 3clv RAB5 PROTEIN,
PUTATIVE
(Plasmodium
falciparum) 		3 / 3 SER A  21
LYS A  20
SER A  22
 GDP  A 211 (-2.6A)
GDP  A 211 (-2.8A)
GDP  A 211 (-2.7A)
 0.81A 6az3P-3clvA:
undetectable		 6az3P-3clvA:
19.25