SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cm0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3cm0 ADENYLATE KINASE
(Thermus
thermophilus) 		3 / 3 THR A 151
ASP A  83
SER A  34
 None
 0.62A 2nxeA-3cm0A:
undetectable		 2nxeA-3cm0A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3cm0 ADENYLATE KINASE
(Thermus
thermophilus) 		3 / 3 THR A 151
ASP A  83
SER A  34
 None
 0.65A 2nxeB-3cm0A:
2.2		 2nxeB-3cm0A:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 3cm0 ADENYLATE KINASE
(Thermus
thermophilus) 		4 / 7 ILE A   8
ILE A  68
LEU A  69
ILE A  72
 None
 0.81A 2q83A-3cm0A:
undetectable		 2q83A-3cm0A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 3cm0 ADENYLATE KINASE
(Thermus
thermophilus) 		3 / 3 PRO A  13
GLU A 145
TYR A 147
 None
 0.71A 2zmbA-3cm0A:
undetectable		 2zmbA-3cm0A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3cm0 ADENYLATE KINASE
(Thermus
thermophilus) 		4 / 8 ILE A  81
LEU A  24
LYS A 165
GLY A 185
 None
 1.01A 3selX-3cm0A:
undetectable		 3selX-3cm0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3cm0 ADENYLATE KINASE
(Thermus
thermophilus) 		4 / 8 PRO A 153
GLU A 159
LEU A 164
LEU A 111
 None
 0.97A 4jjkA-3cm0A:
4.8		 4jjkA-3cm0A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 3cm0 ADENYLATE KINASE
(Thermus
thermophilus) 		5 / 12 ARG A  73
ALA A   6
ILE A  38
HIS A  42
LEU A  69
 None
 1.14A 4l9qA-3cm0A:
undetectable		 4l9qA-3cm0A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3cm0 ADENYLATE KINASE
(Thermus
thermophilus) 		5 / 12 GLY A  16
GLN A  20
ALA A  15
VAL A 114
ILE A 180
 None
 1.15A 4pd5A-3cm0A:
undetectable		 4pd5A-3cm0A:
19.32