SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cm1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3cm1 SSGA-LIKE
SPORULATION-SPECIFIC
CELL DIVISION
PROTEIN
(Thermobifida
fusca) 		4 / 7 TYR A 126
GLN A 122
TYR A  32
ILE A   8
 None
 1.23A 2ph9A-3cm1A:
undetectable
2ph9B-3cm1A:
undetectable		 2ph9A-3cm1A:
22.27
2ph9B-3cm1A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3cm1 SSGA-LIKE
SPORULATION-SPECIFIC
CELL DIVISION
PROTEIN
(Thermobifida
fusca) 		4 / 6 PHE A  44
LEU A  61
ALA A 102
ALA A  28
 None
 0.98A 2vcvK-3cm1A:
undetectable		 2vcvK-3cm1A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_E_VDYE6178_1
(VITAMIN D
HYDROXYLASE)		 3cm1 SSGA-LIKE
SPORULATION-SPECIFIC
CELL DIVISION
PROTEIN
(Thermobifida
fusca) 		5 / 12 ILE A  89
ILE A  40
ALA A  42
VAL A  12
LEU A 107
 None
 1.18A 3a51E-3cm1A:
undetectable		 3a51E-3cm1A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cm1 SSGA-LIKE
SPORULATION-SPECIFIC
CELL DIVISION
PROTEIN
(Thermobifida
fusca) 		4 / 8 ASN A  88
ARG A  75
ILE A  76
GLY A  70
 None
 0.99A 5nzxA-3cm1A:
undetectable		 5nzxA-3cm1A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3cm1 SSGA-LIKE
SPORULATION-SPECIFIC
CELL DIVISION
PROTEIN
(Thermobifida
fusca) 		4 / 7 THR A 114
ARG A  29
HIS A  45
ASP A  31
 None
 1.30A 6mn4E-3cm1A:
undetectable		 6mn4E-3cm1A:
22.64