SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 10 GLU A 341
GLU A 342
ALA A 345
LEU A 346
MET A 366
 None
 1.42A 1a29A-3cmgA:
undetectable		 1a29A-3cmgA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 10 PHE A 106
VAL A 150
VAL A 177
ILE A 181
LEU A  91
 None
 1.04A 1fe2A-3cmgA:
undetectable		 1fe2A-3cmgA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 PHE A 560
ALA A 379
GLU A 380
LEU A 357
 None
 0.66A 1hk2A-3cmgA:
undetectable		 1hk2A-3cmgA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.91A 1jnoA-3cmgA:
undetectable		 1jnoA-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.91A 1jnoB-3cmgA:
undetectable		 1jnoB-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.72A 1jo3A-3cmgA:
undetectable		 1jo3A-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.72A 1jo3B-3cmgA:
undetectable		 1jo3B-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.90A 1jo4A-3cmgA:
undetectable		 1jo4A-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.90A 1jo4B-3cmgA:
undetectable		 1jo4B-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.86A 1ng8A-3cmgA:
undetectable		 1ng8A-3cmgA:
5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.86A 1ng8B-3cmgA:
undetectable		 1ng8B-3cmgA:
5.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.89A 1nrmA-3cmgA:
undetectable		 1nrmA-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.89A 1nrmB-3cmgA:
undetectable		 1nrmB-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.85A 1nruA-3cmgA:
undetectable		 1nruA-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.85A 1nruB-3cmgA:
undetectable		 1nruB-3cmgA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.91A 1nt5A-3cmgA:
undetectable		 1nt5A-3cmgA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ALA A 651
VAL A 658
TRP A 659
 None
 0.91A 1nt5B-3cmgA:
undetectable		 1nt5B-3cmgA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 GLY A 385
ASN A 428
GLU A 510
ASP A 166
HIS A 359
 CL  A 820 ( 4.6A)
PO4  A 810 (-3.1A)
PO4  A 810 (-2.7A)
None
PO4  A 810 (-4.2A)
 1.46A 1qu3A-3cmgA:
undetectable		 1qu3A-3cmgA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 GLY A 385
ASN A 428
GLU A 510
HIS A 359
VAL A 164
 CL  A 820 ( 4.6A)
PO4  A 810 (-3.1A)
PO4  A 810 (-2.7A)
PO4  A 810 (-4.2A)
None
 1.42A 1qu3A-3cmgA:
undetectable		 1qu3A-3cmgA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 GLU A 410
GLU A 451
LEU A 426
 None
MPD  A 800 ( 4.3A)
None
 0.62A 1v8bA-3cmgA:
undetectable		 1v8bA-3cmgA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 ILE A 355
VAL A 322
ASN A 563
MET A 370
ARG A 590
 None
 1.32A 1wsvA-3cmgA:
undetectable		 1wsvA-3cmgA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 TRP A 604
THR A 559
TYR A 511
 None
 0.88A 2a3aA-3cmgA:
5.3		 2a3aA-3cmgA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 TRP A 604
THR A 559
TYR A 511
 None
 0.89A 2a3aB-3cmgA:
5.1		 2a3aB-3cmgA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 TRP A 604
THR A 559
TYR A 511
 None
 0.85A 2a3bA-3cmgA:
5.2		 2a3bA-3cmgA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 10 MET A 370
ALA A 345
GLU A 342
LEU A 346
ARG A 328
 None
 1.45A 2ocfA-3cmgA:
undetectable		 2ocfA-3cmgA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 VAL A 384
ASN A 428
PHE A 567
HIS A 325
HIS A 571
 None
PO4  A 810 (-3.1A)
None
None
None
 1.31A 2x2iB-3cmgA:
9.4		 2x2iB-3cmgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 VAL A 384
ASN A 428
PHE A 567
HIS A 325
HIS A 571
 None
PO4  A 810 (-3.1A)
None
None
None
 1.29A 2x2iC-3cmgA:
6.4		 2x2iC-3cmgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 VAL A 384
ASN A 428
PHE A 567
HIS A 325
HIS A 571
 None
PO4  A 810 (-3.1A)
None
None
None
 1.32A 2x2iD-3cmgA:
10.2		 2x2iD-3cmgA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 SER A 523
THR A 627
PHE A 631
 None
 0.54A 2x91A-3cmgA:
undetectable		 2x91A-3cmgA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 GLY A 531
ALA A 569
ASP A 576
GLY A  76
ASN A 581
 None
 1.31A 3jzjA-3cmgA:
undetectable		 3jzjA-3cmgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 ASN A  48
LEU A 149
SER A 147
ARG A 119
 None
 1.10A 3kp2A-3cmgA:
undetectable
3kp2B-3cmgA:
undetectable		 3kp2A-3cmgA:
13.43
3kp2B-3cmgA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ARG A 455
ASP A 368
GLN A 278
 None
 0.88A 3lcvB-3cmgA:
undetectable		 3lcvB-3cmgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEK_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 GLY A 171
ASN A  69
TYR A  80
ASN A 333
TYR A 360
 None
 1.35A 3mekA-3cmgA:
undetectable		 3mekA-3cmgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 ASP A  40
LEU A 180
ASP A 107
ASP A 176
 None
 0.91A 3n2oC-3cmgA:
6.6
3n2oD-3cmgA:
6.2		 3n2oC-3cmgA:
22.27
3n2oD-3cmgA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 HIS A 418
ASP A  40
LEU A 180
ASP A 107
 None
 1.05A 3n2oC-3cmgA:
6.6
3n2oD-3cmgA:
6.2		 3n2oC-3cmgA:
22.27
3n2oD-3cmgA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 ARG A 151
ASN A  86
ASN A 153
TRP A  68
 None
 1.16A 3n62A-3cmgA:
undetectable		 3n62A-3cmgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 ARG A 151
ASN A  86
ASN A 153
TRP A  68
 None
 1.21A 3n62B-3cmgA:
undetectable		 3n62B-3cmgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 ARG A 151
ASN A  86
ASN A 153
TRP A  68
 None
 1.20A 3n66B-3cmgA:
undetectable		 3n66B-3cmgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 PHE A 132
ARG A 126
ILE A 160
GLY A 130
 None
 0.91A 3n9jA-3cmgA:
undetectable		 3n9jA-3cmgA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 ILE A 181
LEU A 179
TYR A 142
ILE A  93
 None
 0.96A 3p50A-3cmgA:
3.4		 3p50A-3cmgA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 ILE A 181
LEU A 179
TYR A 142
ILE A  93
 None
 0.96A 3p50B-3cmgA:
3.2		 3p50B-3cmgA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 ILE A 181
LEU A 179
TYR A 142
ILE A  93
 None
 0.97A 3p50C-3cmgA:
3.3		 3p50C-3cmgA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 ILE A 181
LEU A 179
TYR A 142
ILE A  93
 None
 0.97A 3p50E-3cmgA:
3.3		 3p50E-3cmgA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ILE A 187
VAL A 293
ARG A  38
 None
 0.73A 3p73A-3cmgA:
1.8		 3p73A-3cmgA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 GLN A 414
GLU A 410
GLY A 128
GLY A 108
ALA A 131
 None
 1.15A 3tegA-3cmgA:
undetectable		 3tegA-3cmgA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 LEU A 139
GLY A 123
VAL A 148
ILE A 133
ILE A 117
 None
 0.92A 3tkgD-3cmgA:
undetectable		 3tkgD-3cmgA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 ARG A 300
VAL A 279
ASP A 371
ARG A 455
 None
 1.18A 3uy4A-3cmgA:
2.2		 3uy4A-3cmgA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 THR A 627
VAL A 658
GLU A 615
 None
 0.56A 3v4tA-3cmgA:
undetectable
3v4tD-3cmgA:
undetectable		 3v4tA-3cmgA:
21.38
3v4tD-3cmgA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ARG A 151
ARG A 119
ILE A  84
 None
 0.88A 4b7qA-3cmgA:
undetectable		 4b7qA-3cmgA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ARG A 151
ARG A 119
ILE A  84
 None
 0.77A 4b7qC-3cmgA:
undetectable		 4b7qC-3cmgA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ASN A 153
LEU A 149
PHE A  51
 None
 0.73A 4dajB-3cmgA:
undetectable		 4dajB-3cmgA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 7 LEU A 163
PHE A 400
LYS A 405
GLY A 404
 None
 1.00A 4hbfA-3cmgA:
undetectable		 4hbfA-3cmgA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 ALA A 529
GLY A 481
GLY A 484
THR A 559
GLY A 512
 None
 0.98A 4n48B-3cmgA:
undetectable		 4n48B-3cmgA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 GLN A 338
HIS A 339
ARG A 328
 None
 1.16A 4qyqA-3cmgA:
undetectable		 4qyqA-3cmgA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 GLN A 338
HIS A 339
ARG A 328
 None
 1.21A 4qyqB-3cmgA:
undetectable		 4qyqB-3cmgA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 THR A 185
ASN A 219
SER A 218
 MPD  A 801 ( 3.8A)
MPD  A 801 ( 3.9A)
None
 0.69A 4tvtA-3cmgA:
undetectable		 4tvtA-3cmgA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 10 GLY A 321
VAL A 322
THR A 377
VAL A 352
LEU A 357
 None
 1.34A 4yb6C-3cmgA:
undetectable
4yb6F-3cmgA:
undetectable		 4yb6C-3cmgA:
20.18
4yb6F-3cmgA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 10 LEU A 357
GLY A 321
VAL A 322
THR A 377
VAL A 352
 None
 1.35A 4yb6A-3cmgA:
undetectable
4yb6D-3cmgA:
undetectable		 4yb6A-3cmgA:
20.18
4yb6D-3cmgA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 10 LEU A 357
GLY A 321
VAL A 322
THR A 377
VAL A 352
 None
 1.33A 4yb6D-3cmgA:
undetectable
4yb6E-3cmgA:
undetectable		 4yb6D-3cmgA:
20.18
4yb6E-3cmgA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCM_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 GLY A 171
ASN A  69
TYR A  80
ASN A 333
TYR A 360
 None
 1.39A 5ccmA-3cmgA:
undetectable		 5ccmA-3cmgA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ASN A 477
ALA A 460
ARG A 356
 PO4  A 810 (-4.4A)
None
None
 0.65A 5cvtB-3cmgA:
2.7		 5cvtB-3cmgA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 PRO A 265
ILE A 281
SER A 205
 None
 0.73A 5fsaA-3cmgA:
undetectable		 5fsaA-3cmgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 ARG A 590
HIS A 340
ARG A 324
 None
 1.14A 5iaoC-3cmgA:
undetectable		 5iaoC-3cmgA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 10 PHE A  51
ILE A  84
PHE A  49
GLY A 171
GLY A 172
 None
None
MPD  A 802 (-4.2A)
None
None
 1.04A 5lbtA-3cmgA:
undetectable
5lbtB-3cmgA:
undetectable		 5lbtA-3cmgA:
17.54
5lbtB-3cmgA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 VAL A 164
GLY A 165
ASP A 166
GLY A 387
HIS A 571
 None
 1.14A 5nnaA-3cmgA:
undetectable		 5nnaA-3cmgA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 VAL A 164
GLY A 165
ASP A 166
GLY A 387
HIS A 571
 None
 1.15A 5nnaB-3cmgA:
1.6		 5nnaB-3cmgA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 VAL A 164
GLY A 165
ASP A 166
GLY A 387
HIS A 571
 None
 1.16A 5nnaC-3cmgA:
1.8		 5nnaC-3cmgA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 VAL A 164
GLY A 165
ASP A 166
GLY A 387
HIS A 571
 None
 1.16A 5nnaD-3cmgA:
1.6		 5nnaD-3cmgA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 9 LEU A 104
PHE A 106
VAL A 115
HIS A 125
ILE A 122
 None
 1.06A 5om2A-3cmgA:
undetectable
5om2B-3cmgA:
undetectable		 5om2A-3cmgA:
9.65
5om2B-3cmgA:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXD_A_SAMA501_0
(SMYD3
METHYLTRANSFERASE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 GLY A 171
ASN A  69
TYR A  80
ASN A 333
TYR A 360
 None
 1.36A 5xxdA-3cmgA:
undetectable		 5xxdA-3cmgA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJO_A_SAMA505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 GLY A 171
ASN A  69
TYR A  80
ASN A 333
TYR A 360
 None
 1.36A 5yjoA-3cmgA:
undetectable		 5yjoA-3cmgA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 LEU A 335
ASN A 563
LEU A 357
 None
 0.75A 6exiD-3cmgA:
undetectable		 6exiD-3cmgA:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		5 / 12 ARG A 244
VAL A 246
LEU A 248
LEU A 258
LEU A 217
 None
None
MPD  A 801 ( 4.7A)
None
None
 0.86A 6f6iA-3cmgA:
undetectable
6f6iB-3cmgA:
undetectable		 6f6iA-3cmgA:
8.62
6f6iB-3cmgA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		3 / 3 THR A 632
ALA A 637
LYS A 648
 None
 0.75A 6fgdA-3cmgA:
undetectable		 6fgdA-3cmgA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3cmg PUTATIVE
BETA-GALACTOSIDASE
(Bacteroides
fragilis) 		4 / 8 ASP A 582
HIS A 325
ARG A 572
ASP A 166
 None
 1.17A 6mn4A-3cmgA:
undetectable		 6mn4A-3cmgA:
19.65