SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3cmi PEROXIREDOXIN HYR1
(Saccharomyces
cerevisiae) 		4 / 8 MET A  93
VAL A  88
THR A  89
PHE A  90
 None
 1.15A 2kotB-3cmiA:
undetectable		 2kotB-3cmiA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3cmi PEROXIREDOXIN HYR1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A  20
TYR A   5
LYS A  25
 None
 1.21A 2othA-3cmiA:
undetectable		 2othA-3cmiA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3cmi PEROXIREDOXIN HYR1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A  98
ARG A 141
VAL A 106
PHE A 130
 None
 1.30A 5addA-3cmiA:
undetectable
5addB-3cmiA:
undetectable		 5addA-3cmiA:
19.09
5addB-3cmiA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3cmi PEROXIREDOXIN HYR1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A  98
ARG A 141
VAL A 106
PHE A 130
 None
 1.40A 5adeA-3cmiA:
undetectable
5adeB-3cmiA:
undetectable		 5adeA-3cmiA:
19.09
5adeB-3cmiA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3cmi PEROXIREDOXIN HYR1
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 159
LEU A 131
TYR A  49
GLN A  21
 None
 1.16A 5hbsA-3cmiA:
undetectable		 5hbsA-3cmiA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3cmi PEROXIREDOXIN HYR1
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 124
SER A 144
SER A 143
 None
 1.06A 6gbfA-3cmiA:
undetectable		 6gbfA-3cmiA:
15.65