SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cmu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A 121
PRO A 151
THR A 150
 None
 0.88A 1a7yB-3cmuA:
undetectable		 1a7yB-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A1121
PRO A1151
THR A1150
 None
 0.89A 1a7yB-3cmuA:
undetectable		 1a7yB-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A2121
PRO A2151
THR A2150
 None
 0.89A 1a7yB-3cmuA:
undetectable		 1a7yB-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A5121
PRO A5151
THR A5150
 None
 0.89A 1a7yB-3cmuA:
undetectable		 1a7yB-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A 263
GLU A 273
LYS A 310
LEU A 107
GLY A  43
 None
 1.35A 1d4fB-3cmuA:
undetectable		 1d4fB-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A1263
GLU A1273
LYS A1310
LEU A1107
GLY A1043
 None
 1.31A 1d4fB-3cmuA:
undetectable		 1d4fB-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A2263
GLU A2273
LYS A2310
LEU A2107
GLY A2043
 None
 1.30A 1d4fB-3cmuA:
undetectable		 1d4fB-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A3263
GLU A3273
LYS A3310
LEU A3107
GLY A3043
 None
 1.31A 1d4fB-3cmuA:
undetectable		 1d4fB-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A4263
GLU A4273
LYS A4310
LEU A4107
GLY A4043
 None
 1.32A 1d4fB-3cmuA:
undetectable		 1d4fB-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A5263
GLU A5273
LYS A5310
LEU A5107
GLY A5043
 None
 1.39A 1d4fB-3cmuA:
undetectable		 1d4fB-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A 263
GLU A 273
LYS A 310
LEU A 107
GLY A  43
 None
 1.28A 1d4fD-3cmuA:
undetectable		 1d4fD-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A1263
GLU A1273
LYS A1310
LEU A1107
GLY A1043
 None
 1.24A 1d4fD-3cmuA:
undetectable		 1d4fD-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A2263
GLU A2273
LYS A2310
LEU A2107
GLY A2043
 None
 1.23A 1d4fD-3cmuA:
undetectable		 1d4fD-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A3263
GLU A3273
LYS A3310
LEU A3107
GLY A3043
 None
 1.25A 1d4fD-3cmuA:
undetectable		 1d4fD-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A4263
GLU A4273
LYS A4310
LEU A4107
GLY A4043
 None
 1.24A 1d4fD-3cmuA:
undetectable		 1d4fD-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A5263
GLU A5273
LYS A5310
LEU A5107
GLY A5043
 None
 1.30A 1d4fD-3cmuA:
undetectable		 1d4fD-3cmuA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 8 LEU A1215
LEU A1149
GLY A1122
ILE A 159
MET A1175
 None
 1.50A 1n13A-3cmuA:
undetectable
1n13F-3cmuA:
undetectable		 1n13A-3cmuA:
2.68
1n13F-3cmuA:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A  99
ALA A  98
GLU A  96
LEU A 107
ILE A 102
 None
None
ALF  A 501 ( 2.4A)
None
None
 1.01A 1s9pD-3cmuA:
undetectable		 1s9pD-3cmuA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A2099
ALA A2098
GLU A2096
LEU A2107
ILE A2102
 None
None
ALF  A2501 ( 2.5A)
None
None
 1.01A 1s9pD-3cmuA:
undetectable		 1s9pD-3cmuA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A3099
ALA A3098
GLU A3096
LEU A3107
ILE A3102
 None
None
ALF  A3501 ( 2.7A)
None
None
 1.01A 1s9pD-3cmuA:
undetectable		 1s9pD-3cmuA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A 143
LEU A 166
ALA A 167
ALA A 174
ALA A 214
 None
 1.09A 1sa1C-3cmuA:
undetectable
1sa1D-3cmuA:
undetectable		 1sa1C-3cmuA:
12.85
1sa1D-3cmuA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A1143
LEU A1166
ALA A1167
ALA A1174
ALA A1214
 None
 1.09A 1sa1C-3cmuA:
undetectable
1sa1D-3cmuA:
undetectable		 1sa1C-3cmuA:
12.85
1sa1D-3cmuA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A2143
LEU A2166
ALA A2167
ALA A2174
ALA A2214
 None
 1.10A 1sa1C-3cmuA:
undetectable
1sa1D-3cmuA:
undetectable		 1sa1C-3cmuA:
12.85
1sa1D-3cmuA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A3143
LEU A3166
ALA A3167
ALA A3174
ALA A3214
 None
 1.10A 1sa1C-3cmuA:
undetectable
1sa1D-3cmuA:
undetectable		 1sa1C-3cmuA:
12.85
1sa1D-3cmuA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A4143
LEU A4166
ALA A4167
ALA A4174
ALA A4214
 None
 1.10A 1sa1C-3cmuA:
undetectable
1sa1D-3cmuA:
undetectable		 1sa1C-3cmuA:
12.85
1sa1D-3cmuA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A5143
LEU A5166
ALA A5167
ALA A5174
ALA A5214
 None
 1.09A 1sa1C-3cmuA:
undetectable
1sa1D-3cmuA:
undetectable		 1sa1C-3cmuA:
12.85
1sa1D-3cmuA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A 150
THR A 121
PRO A 151
 None
 0.86A 1unjF-3cmuA:
undetectable		 1unjF-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A1150
THR A1121
PRO A1151
 None
 0.86A 1unjF-3cmuA:
undetectable		 1unjF-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A 150
THR A 121
PRO A 151
 None
 0.87A 1unjL-3cmuA:
undetectable		 1unjL-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A 121
PRO A 151
THR A 150
 None
 0.86A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A1121
PRO A1151
THR A1150
 None
 0.86A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A2121
PRO A2151
THR A2150
 None
 0.86A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A3121
PRO A3151
THR A3150
 None
 0.87A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A5121
PRO A5151
THR A5150
 None
 0.86A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A 150
THR A 121
PRO A 151
 None
 0.84A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A1150
THR A1121
PRO A1151
 None
 0.84A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A2150
THR A2121
PRO A2151
 None
 0.85A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A3150
THR A3121
PRO A3151
 None
 0.85A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A4150
THR A4121
PRO A4151
 None
 0.85A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A5150
THR A5121
PRO A5151
 None
 0.85A 1unjR-3cmuA:
undetectable		 1unjR-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A 121
PRO A 151
THR A 150
 None
 0.86A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A1121
PRO A1151
THR A1150
 None
 0.87A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A2121
PRO A2151
THR A2150
 None
 0.87A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A5121
PRO A5151
THR A5150
 None
 0.87A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A 150
THR A 121
PRO A 151
 None
 0.85A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A1150
THR A1121
PRO A1151
 None
 0.85A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A2150
THR A2121
PRO A2151
 None
 0.86A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A3150
THR A3121
PRO A3151
 None
 0.86A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A4150
THR A4121
PRO A4151
 None
 0.86A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A5150
THR A5121
PRO A5151
 None
 0.85A 1unjX-3cmuA:
undetectable		 1unjX-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A 121
PRO A 151
THR A 150
 None
 0.87A 1unmF-3cmuA:
undetectable		 1unmF-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A1121
PRO A1151
THR A1150
 None
 0.87A 1unmF-3cmuA:
undetectable		 1unmF-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A2121
PRO A2151
THR A2150
 None
 0.87A 1unmF-3cmuA:
undetectable		 1unmF-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 THR A5121
PRO A5151
THR A5150
 None
 0.87A 1unmF-3cmuA:
undetectable		 1unmF-3cmuA:
0.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 LYS A1248
THR A 209
SER A  70
ARG A 226
 ALF  A 501 (-2.1A)
None
ADP  A 502 (-2.9A)
None
 1.08A 1xr2B-3cmuA:
undetectable		 1xr2B-3cmuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 LYS A2248
THR A1209
SER A1070
ARG A1226
 ALF  A1501 (-2.3A)
None
ADP  A1502 (-2.9A)
None
 1.07A 1xr2B-3cmuA:
undetectable		 1xr2B-3cmuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 LYS A3248
THR A2209
SER A2070
ARG A2226
 ALF  A2501 (-2.2A)
None
ADP  A2502 (-2.6A)
None
 1.08A 1xr2B-3cmuA:
undetectable		 1xr2B-3cmuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 LYS A4248
THR A3209
SER A3070
ARG A3226
 ALF  A3501 (-2.3A)
None
ADP  A3502 (-2.7A)
None
 1.06A 1xr2B-3cmuA:
undetectable		 1xr2B-3cmuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 LYS A5248
THR A4209
SER A4070
ARG A4226
 ALF  A4501 (-2.6A)
None
ADP  A4502 (-2.7A)
None
 1.07A 1xr2B-3cmuA:
undetectable		 1xr2B-3cmuA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 SER A1333
ASP A1032
CYH A 116
 None
 1.10A 2br4E-3cmuA:
undetectable		 2br4E-3cmuA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A  80
ALA A  81
ARG A  85
LEU A 107
ILE A 262
 None
 1.10A 2h77A-3cmuA:
undetectable		 2h77A-3cmuA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A1080
ALA A1081
ARG A1085
LEU A1107
ILE A1262
 None
 1.11A 2h77A-3cmuA:
undetectable		 2h77A-3cmuA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A2080
ALA A2081
ARG A2085
LEU A2107
ILE A2262
 None
 1.10A 2h77A-3cmuA:
undetectable		 2h77A-3cmuA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A3080
ALA A3081
ARG A3085
LEU A3107
ILE A3262
 None
 1.11A 2h77A-3cmuA:
undetectable		 2h77A-3cmuA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A4080
ALA A4081
ARG A4085
LEU A4107
ILE A4262
 None
 1.11A 2h77A-3cmuA:
undetectable		 2h77A-3cmuA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A5080
ALA A5081
ARG A5085
LEU A5107
ILE A5262
 None
 1.10A 2h77A-3cmuA:
undetectable		 2h77A-3cmuA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 GLU A 273
LEU A 274
LEU A  45
LEU A  47
ILE A  40
 None
 1.14A 2qxsA-3cmuA:
undetectable		 2qxsA-3cmuA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 ARG A3226
GLU A2068
SER A3070
 None
None
ADP  A3502 (-2.7A)
 0.88A 2xkkA-3cmuA:
undetectable
2xkkC-3cmuA:
undetectable		 2xkkA-3cmuA:
17.81
2xkkC-3cmuA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 ARG A4226
GLU A3068
SER A4070
 None
None
ADP  A4502 (-2.7A)
 0.91A 2xkkA-3cmuA:
undetectable
2xkkC-3cmuA:
undetectable		 2xkkA-3cmuA:
17.81
2xkkC-3cmuA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ARG A 222
PHE A 191
PRO A  57
ILE A 192
VAL A 143
 None
 1.28A 2zznA-3cmuA:
undetectable		 2zznA-3cmuA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ARG A1222
PHE A1191
PRO A1057
ILE A1192
VAL A1143
 None
 1.28A 2zznA-3cmuA:
undetectable		 2zznA-3cmuA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ARG A2222
PHE A2191
PRO A2057
ILE A2192
VAL A2143
 None
 1.28A 2zznA-3cmuA:
undetectable		 2zznA-3cmuA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ARG A3222
PHE A3191
PRO A3057
ILE A3192
VAL A3143
 None
 1.28A 2zznA-3cmuA:
undetectable		 2zznA-3cmuA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ARG A4222
PHE A4191
PRO A4057
ILE A4192
VAL A4143
 None
 1.28A 2zznA-3cmuA:
undetectable		 2zznA-3cmuA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ARG A5222
PHE A5191
PRO A5057
ILE A5192
VAL A5143
 None
 1.28A 2zznA-3cmuA:
undetectable		 2zznA-3cmuA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 GLY A3180
ASP A3139
ILE A3190
LEU A3056
ASN A3186
 None
 1.19A 3eeoA-3cmuA:
undetectable		 3eeoA-3cmuA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 11 ALA A2133
ARG A2134
ILE A2141
LEU A2178
LEU A2126
 None
 1.21A 3kw2A-3cmuA:
undetectable		 3kw2A-3cmuA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 11 ALA A3133
ARG A3134
ILE A3141
LEU A3178
LEU A3126
 None
 1.20A 3kw2A-3cmuA:
undetectable		 3kw2A-3cmuA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 11 ALA A4133
ARG A4134
ILE A4141
LEU A4178
LEU A4126
 None
 1.20A 3kw2A-3cmuA:
undetectable		 3kw2A-3cmuA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 11 ALA A5133
ARG A5134
ILE A5141
LEU A5178
LEU A5126
 None
 1.21A 3kw2A-3cmuA:
undetectable		 3kw2A-3cmuA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A 143
ILE A 128
ALA A 125
GLU A 127
ALA A 174
 None
 0.82A 3mdvB-3cmuA:
undetectable		 3mdvB-3cmuA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A1143
ILE A1128
ALA A1125
GLU A1127
ALA A1174
 None
 0.82A 3mdvB-3cmuA:
undetectable		 3mdvB-3cmuA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A2143
ILE A2128
ALA A2125
GLU A2127
ALA A2174
 None
 0.82A 3mdvB-3cmuA:
undetectable		 3mdvB-3cmuA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A3143
ILE A3128
ALA A3125
GLU A3127
ALA A3174
 None
 0.83A 3mdvB-3cmuA:
undetectable		 3mdvB-3cmuA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A4143
ILE A4128
ALA A4125
GLU A4127
ALA A4174
 None
 0.83A 3mdvB-3cmuA:
undetectable		 3mdvB-3cmuA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 VAL A5143
ILE A5128
ALA A5125
GLU A5127
ALA A5174
 None
 0.83A 3mdvB-3cmuA:
undetectable		 3mdvB-3cmuA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 11 THR A1074
ALA A1081
GLY A1108
ALA A1104
ASP A1100
 ADP  A1502 (-3.5A)
None
None
None
ADP  A1502 (-4.0A)
 1.35A 3mg0H-3cmuA:
undetectable
3mg0I-3cmuA:
undetectable		 3mg0H-3cmuA:
8.39
3mg0I-3cmuA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 11 THR A2074
ALA A2081
GLY A2108
ALA A2104
ASP A2100
 ADP  A2502 (-3.9A)
None
None
None
ADP  A2502 (-4.2A)
 1.35A 3mg0H-3cmuA:
undetectable
3mg0I-3cmuA:
undetectable		 3mg0H-3cmuA:
8.39
3mg0I-3cmuA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 11 THR A3074
ALA A3081
GLY A3108
ALA A3104
ASP A3100
 ADP  A3502 (-3.7A)
None
None
None
ADP  A3502 (-4.4A)
 1.35A 3mg0H-3cmuA:
undetectable
3mg0I-3cmuA:
undetectable		 3mg0H-3cmuA:
8.39
3mg0I-3cmuA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 11 THR A5074
ALA A5081
GLY A5108
ALA A5104
ASP A5100
 ADP  A5502 (-3.9A)
None
None
None
ADP  A5502 (-3.8A)
 1.36A 3mg0H-3cmuA:
undetectable
3mg0I-3cmuA:
undetectable		 3mg0H-3cmuA:
8.39
3mg0I-3cmuA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		6 / 11 ALA A1050
ALA A1258
VAL A1246
ALA A1053
GLY A1054
SER A1329
 None
 1.34A 3mg0K-3cmuA:
undetectable
3mg0L-3cmuA:
undetectable		 3mg0K-3cmuA:
7.39
3mg0L-3cmuA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		6 / 11 ALA A3050
ALA A3258
VAL A3246
ALA A3053
GLY A3054
SER A3329
 None
 1.33A 3mg0K-3cmuA:
undetectable
3mg0L-3cmuA:
undetectable		 3mg0K-3cmuA:
7.39
3mg0L-3cmuA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		6 / 12 ALA A3050
ALA A3258
VAL A3246
ALA A3053
GLY A3054
SER A3329
 None
 1.34A 3mg0Y-3cmuA:
undetectable
3mg0Z-3cmuA:
undetectable		 3mg0Y-3cmuA:
7.39
3mg0Z-3cmuA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 PHE A 260
ASN A 269
ILE A 268
GLY A 267
THR A  74
 None
None
None
None
ADP  A 502 (-3.9A)
 1.22A 3t3rB-3cmuA:
undetectable		 3t3rB-3cmuA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 PHE A1260
ASN A1269
ILE A1268
GLY A1267
THR A1074
 None
None
None
None
ADP  A1502 (-3.5A)
 1.23A 3t3rB-3cmuA:
undetectable		 3t3rB-3cmuA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 PHE A2260
ASN A2269
ILE A2268
GLY A2267
THR A2074
 None
None
None
None
ADP  A2502 (-3.9A)
 1.24A 3t3rB-3cmuA:
undetectable		 3t3rB-3cmuA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 PHE A3260
ASN A3269
ILE A3268
GLY A3267
THR A3074
 None
None
None
None
ADP  A3502 (-3.7A)
 1.24A 3t3rB-3cmuA:
undetectable		 3t3rB-3cmuA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 PHE A4260
ASN A4269
ILE A4268
GLY A4267
THR A4074
 None
None
None
None
ADP  A4502 (-3.8A)
 1.22A 3t3rB-3cmuA:
undetectable		 3t3rB-3cmuA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 PHE A5260
ASN A5269
ILE A5268
GLY A5267
THR A5074
 None
None
None
None
ADP  A5502 (-3.9A)
 1.17A 3t3rB-3cmuA:
undetectable		 3t3rB-3cmuA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 PHE A2260
ASN A2269
ILE A2268
GLY A2267
THR A2074
 None
None
None
None
ADP  A2502 (-3.9A)
 1.24A 3t3rD-3cmuA:
undetectable		 3t3rD-3cmuA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 GLY A  55
LEU A  45
LEU A 328
LEU A  51
ILE A  49
 None
 1.17A 3wdmB-3cmuA:
undetectable		 3wdmB-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 GLY A1055
LEU A1045
LEU A1328
LEU A1051
ILE A1049
 None
 1.15A 3wdmB-3cmuA:
undetectable		 3wdmB-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 GLY A2055
LEU A2045
LEU A2328
LEU A2051
ILE A2049
 None
 1.11A 3wdmB-3cmuA:
undetectable		 3wdmB-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 GLY A3055
LEU A3045
LEU A3328
LEU A3051
ILE A3049
 None
 1.16A 3wdmB-3cmuA:
undetectable		 3wdmB-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 GLY A4055
LEU A4045
LEU A4328
LEU A4051
ILE A4049
 None
 1.14A 3wdmB-3cmuA:
undetectable		 3wdmB-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 GLY A5055
LEU A5045
LEU A5328
LEU A5051
ILE A5049
 None
 1.19A 3wdmB-3cmuA:
undetectable		 3wdmB-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 GLY A  55
LEU A  45
LEU A 328
LEU A  51
ILE A  49
 None
 1.21A 3wdmC-3cmuA:
undetectable		 3wdmC-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 GLY A2055
LEU A2045
LEU A2328
LEU A2051
ILE A2049
 None
 1.19A 3wdmC-3cmuA:
undetectable		 3wdmC-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 GLY A4055
LEU A4045
LEU A4328
LEU A4051
ILE A4049
 None
 1.22A 3wdmC-3cmuA:
undetectable		 3wdmC-3cmuA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A  64
ASP A  48
GLY A  43
SER A  44
PHE A 260
 None
 1.10A 4bwlC-3cmuA:
undetectable		 4bwlC-3cmuA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A1064
ASP A1048
GLY A1043
SER A1044
PHE A1260
 None
 1.10A 4bwlC-3cmuA:
undetectable		 4bwlC-3cmuA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A4064
ASP A4048
GLY A4043
SER A4044
PHE A4260
 None
 1.10A 4bwlC-3cmuA:
undetectable		 4bwlC-3cmuA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A5064
ASP A5048
GLY A5043
SER A5044
PHE A5260
 None
 1.10A 4bwlC-3cmuA:
undetectable		 4bwlC-3cmuA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A4128
ALA A4125
GLY A4122
GLY A5180
ASN A5181
 None
 1.18A 4jlgA-3cmuA:
undetectable		 4jlgA-3cmuA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A  80
ALA A  81
ARG A  85
LEU A 107
ILE A 262
 None
 1.17A 4lnwA-3cmuA:
undetectable		 4lnwA-3cmuA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A2080
ALA A2081
ARG A2085
LEU A2107
ILE A2262
 None
 1.17A 4lnwA-3cmuA:
undetectable		 4lnwA-3cmuA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A5080
ALA A5081
ARG A5085
LEU A5107
ILE A5262
 None
 1.17A 4lnwA-3cmuA:
undetectable		 4lnwA-3cmuA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 ARG A 134
GLN A1016
GLU A 127
 None
 0.93A 4tvtA-3cmuA:
undetectable		 4tvtA-3cmuA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 ARG A1134
GLN A2016
GLU A1127
 None
 0.92A 4tvtA-3cmuA:
undetectable		 4tvtA-3cmuA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 ARG A2134
GLN A3016
GLU A2127
 None
 0.92A 4tvtA-3cmuA:
undetectable		 4tvtA-3cmuA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		3 / 3 ARG A3134
GLN A4016
GLU A3127
 None
 0.90A 4tvtA-3cmuA:
undetectable		 4tvtA-3cmuA:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 VAL A 143
ILE A 128
ALA A 125
ALA A 174
 None
 0.74A 4zf8A-3cmuA:
undetectable		 4zf8A-3cmuA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 VAL A1143
ILE A1128
ALA A1125
ALA A1174
 None
 0.75A 4zf8A-3cmuA:
undetectable		 4zf8A-3cmuA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 VAL A2143
ILE A2128
ALA A2125
ALA A2174
 None
 0.74A 4zf8A-3cmuA:
undetectable		 4zf8A-3cmuA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 VAL A3143
ILE A3128
ALA A3125
ALA A3174
 None
 0.74A 4zf8A-3cmuA:
undetectable		 4zf8A-3cmuA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 VAL A4143
ILE A4128
ALA A4125
ALA A4174
 None
 0.74A 4zf8A-3cmuA:
undetectable		 4zf8A-3cmuA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 VAL A5143
ILE A5128
ALA A5125
ALA A5174
 None
 0.74A 4zf8A-3cmuA:
undetectable		 4zf8A-3cmuA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 GLY A2054
GLY A2052
PRO A2331
LEU A2047
LYS A2321
 None
 1.15A 5bw4A-3cmuA:
undetectable		 5bw4A-3cmuA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ALA A  82
GLU A 320
GLY A  43
GLY A  55
 None
 0.79A 5e26A-3cmuA:
undetectable
5e26B-3cmuA:
undetectable		 5e26A-3cmuA:
11.25
5e26B-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ALA A1082
GLU A1320
GLY A1043
GLY A1055
 None
 0.82A 5e26A-3cmuA:
undetectable
5e26B-3cmuA:
undetectable		 5e26A-3cmuA:
11.25
5e26B-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ALA A2082
GLU A2320
GLY A2043
GLY A2055
 None
 0.82A 5e26A-3cmuA:
undetectable
5e26B-3cmuA:
undetectable		 5e26A-3cmuA:
11.25
5e26B-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ALA A3082
GLU A3320
GLY A3043
GLY A3055
 None
 0.84A 5e26A-3cmuA:
undetectable
5e26B-3cmuA:
undetectable		 5e26A-3cmuA:
11.25
5e26B-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ALA A4082
GLU A4320
GLY A4043
GLY A4055
 None
 0.83A 5e26A-3cmuA:
undetectable
5e26B-3cmuA:
undetectable		 5e26A-3cmuA:
11.25
5e26B-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 GLU A 320
GLY A  43
GLY A  55
ALA A  82
 None
 0.78A 5e26C-3cmuA:
undetectable
5e26D-3cmuA:
undetectable		 5e26C-3cmuA:
11.25
5e26D-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 GLU A1320
GLY A1043
GLY A1055
ALA A1082
 None
 0.80A 5e26C-3cmuA:
undetectable
5e26D-3cmuA:
undetectable		 5e26C-3cmuA:
11.25
5e26D-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 GLU A2320
GLY A2043
GLY A2055
ALA A2082
 None
 0.80A 5e26C-3cmuA:
undetectable
5e26D-3cmuA:
undetectable		 5e26C-3cmuA:
11.25
5e26D-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 GLU A3320
GLY A3043
GLY A3055
ALA A3082
 None
 0.82A 5e26C-3cmuA:
undetectable
5e26D-3cmuA:
undetectable		 5e26C-3cmuA:
11.25
5e26D-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 GLU A4320
GLY A4043
GLY A4055
ALA A4082
 None
 0.80A 5e26C-3cmuA:
undetectable
5e26D-3cmuA:
undetectable		 5e26C-3cmuA:
11.25
5e26D-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 GLU A5320
GLY A5043
GLY A5055
ALA A5082
 None
 0.89A 5e26C-3cmuA:
undetectable
5e26D-3cmuA:
undetectable		 5e26C-3cmuA:
11.25
5e26D-3cmuA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 ILE A 251
GLY A  55
THR A  42
LEU A  51
LEU A  75
 None
 1.20A 5fhzB-3cmuA:
undetectable		 5fhzB-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 ILE A1251
GLY A1055
THR A1042
LEU A1051
LEU A1075
 None
 1.20A 5fhzB-3cmuA:
undetectable		 5fhzB-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 ILE A2251
GLY A2055
THR A2042
LEU A2051
LEU A2075
 None
 1.20A 5fhzB-3cmuA:
undetectable		 5fhzB-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 ILE A3251
GLY A3055
THR A3042
LEU A3051
LEU A3075
 None
 1.20A 5fhzB-3cmuA:
undetectable		 5fhzB-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 ILE A4251
GLY A4055
THR A4042
LEU A4051
LEU A4075
 None
 1.20A 5fhzB-3cmuA:
undetectable		 5fhzB-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 9 ILE A5251
GLY A5055
THR A5042
LEU A5051
LEU A5075
 None
 1.20A 5fhzB-3cmuA:
undetectable		 5fhzB-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A 251
GLY A  55
THR A  42
LEU A  51
LEU A  75
 None
 1.28A 5fhzC-3cmuA:
undetectable		 5fhzC-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A1251
GLY A1055
THR A1042
LEU A1051
LEU A1075
 None
 1.29A 5fhzC-3cmuA:
undetectable		 5fhzC-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A2251
GLY A2055
THR A2042
LEU A2051
LEU A2075
 None
 1.28A 5fhzC-3cmuA:
undetectable		 5fhzC-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A3251
GLY A3055
THR A3042
LEU A3051
LEU A3075
 None
 1.29A 5fhzC-3cmuA:
undetectable		 5fhzC-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A4251
GLY A4055
THR A4042
LEU A4051
LEU A4075
 None
 1.28A 5fhzC-3cmuA:
undetectable		 5fhzC-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 10 ILE A5251
GLY A5055
THR A5042
LEU A5051
LEU A5075
 None
 1.28A 5fhzC-3cmuA:
undetectable		 5fhzC-3cmuA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 ILE A5049
ALA A5050
SER A5041
GLY A5054
VAL A5323
 None
 1.15A 5i75A-3cmuA:
undetectable		 5i75A-3cmuA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A  74
ALA A  81
GLY A 108
ALA A 104
ASP A 100
 ADP  A 502 (-3.9A)
None
None
None
ADP  A 502 (-4.2A)
 1.37A 5l5zH-3cmuA:
undetectable
5l5zI-3cmuA:
undetectable		 5l5zH-3cmuA:
8.35
5l5zI-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A1074
ALA A1081
GLY A1108
ALA A1104
ASP A1100
 ADP  A1502 (-3.5A)
None
None
None
ADP  A1502 (-4.0A)
 1.36A 5l5zH-3cmuA:
undetectable
5l5zI-3cmuA:
undetectable		 5l5zH-3cmuA:
8.35
5l5zI-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A2074
ALA A2081
GLY A2108
ALA A2104
ASP A2100
 ADP  A2502 (-3.9A)
None
None
None
ADP  A2502 (-4.2A)
 1.36A 5l5zH-3cmuA:
undetectable
5l5zI-3cmuA:
undetectable		 5l5zH-3cmuA:
8.35
5l5zI-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A3074
ALA A3081
GLY A3108
ALA A3104
ASP A3100
 ADP  A3502 (-3.7A)
None
None
None
ADP  A3502 (-4.4A)
 1.36A 5l5zH-3cmuA:
undetectable
5l5zI-3cmuA:
undetectable		 5l5zH-3cmuA:
8.35
5l5zI-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A4074
ALA A4081
GLY A4108
ALA A4104
ASP A4100
 ADP  A4502 (-3.8A)
None
None
None
ADP  A4502 (-4.2A)
 1.37A 5l5zH-3cmuA:
undetectable
5l5zI-3cmuA:
undetectable		 5l5zH-3cmuA:
8.35
5l5zI-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A5074
ALA A5081
GLY A5108
ALA A5104
ASP A5100
 ADP  A5502 (-3.9A)
None
None
None
ADP  A5502 (-3.8A)
 1.37A 5l5zH-3cmuA:
undetectable
5l5zI-3cmuA:
undetectable		 5l5zH-3cmuA:
8.35
5l5zI-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A  74
ALA A  81
GLY A 108
ALA A 104
ASP A 100
 ADP  A 502 (-3.9A)
None
None
None
ADP  A 502 (-4.2A)
 1.38A 5l5zV-3cmuA:
undetectable
5l5zW-3cmuA:
undetectable		 5l5zV-3cmuA:
8.35
5l5zW-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A1074
ALA A1081
GLY A1108
ALA A1104
ASP A1100
 ADP  A1502 (-3.5A)
None
None
None
ADP  A1502 (-4.0A)
 1.37A 5l5zV-3cmuA:
undetectable
5l5zW-3cmuA:
undetectable		 5l5zV-3cmuA:
8.35
5l5zW-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A2074
ALA A2081
GLY A2108
ALA A2104
ASP A2100
 ADP  A2502 (-3.9A)
None
None
None
ADP  A2502 (-4.2A)
 1.37A 5l5zV-3cmuA:
undetectable
5l5zW-3cmuA:
undetectable		 5l5zV-3cmuA:
8.35
5l5zW-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A3074
ALA A3081
GLY A3108
ALA A3104
ASP A3100
 ADP  A3502 (-3.7A)
None
None
None
ADP  A3502 (-4.4A)
 1.37A 5l5zV-3cmuA:
undetectable
5l5zW-3cmuA:
undetectable		 5l5zV-3cmuA:
8.35
5l5zW-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A4074
ALA A4081
GLY A4108
ALA A4104
ASP A4100
 ADP  A4502 (-3.8A)
None
None
None
ADP  A4502 (-4.2A)
 1.38A 5l5zV-3cmuA:
undetectable
5l5zW-3cmuA:
undetectable		 5l5zV-3cmuA:
8.35
5l5zW-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 THR A5074
ALA A5081
GLY A5108
ALA A5104
ASP A5100
 ADP  A5502 (-3.9A)
None
None
None
ADP  A5502 (-3.8A)
 1.37A 5l5zV-3cmuA:
undetectable
5l5zW-3cmuA:
undetectable		 5l5zV-3cmuA:
8.35
5l5zW-3cmuA:
7.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 ASN A1249
PHE A1255
THR A  74
GLY A  71
 None
None
ADP  A 502 (-3.9A)
ADP  A 502 (-3.0A)
 0.95A 5nzxA-3cmuA:
undetectable		 5nzxA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 ASN A2249
PHE A2255
THR A1074
GLY A1071
 None
None
ADP  A1502 (-3.5A)
ADP  A1502 (-2.8A)
 0.97A 5nzxA-3cmuA:
undetectable		 5nzxA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 ASN A4249
PHE A4255
THR A3074
GLY A3071
 None
None
ADP  A3502 (-3.7A)
ADP  A3502 (-2.7A)
 0.96A 5nzxA-3cmuA:
undetectable		 5nzxA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 8 ASN A5249
PHE A5255
THR A4074
GLY A4071
 None
None
ADP  A4502 (-3.8A)
ADP  A4502 (-2.8A)
 0.97A 5nzxA-3cmuA:
undetectable		 5nzxA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ASN A1249
PHE A1255
THR A  74
GLY A  71
 None
None
ADP  A 502 (-3.9A)
ADP  A 502 (-3.0A)
 0.92A 5nzyA-3cmuA:
undetectable		 5nzyA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ASN A2249
PHE A2255
THR A1074
GLY A1071
 None
None
ADP  A1502 (-3.5A)
ADP  A1502 (-2.8A)
 0.95A 5nzyA-3cmuA:
undetectable		 5nzyA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ASN A3249
PHE A3255
THR A2074
GLY A2071
 None
None
ADP  A2502 (-3.9A)
ADP  A2502 (-2.8A)
 1.01A 5nzyA-3cmuA:
undetectable		 5nzyA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ASN A4249
PHE A4255
THR A3074
GLY A3071
 None
None
ADP  A3502 (-3.7A)
ADP  A3502 (-2.7A)
 0.95A 5nzyA-3cmuA:
undetectable		 5nzyA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 7 ASN A5249
PHE A5255
THR A4074
GLY A4071
 None
None
ADP  A4502 (-3.8A)
ADP  A4502 (-2.8A)
 0.95A 5nzyA-3cmuA:
undetectable		 5nzyA-3cmuA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 SER A4185
VAL A4138
ALA A5009
ALA A4137
GLY A4136
 None
 1.20A 5tzoB-3cmuA:
undetectable		 5tzoB-3cmuA:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 SER A1185
VAL A1138
ALA A2009
ALA A1137
GLY A1136
 None
 1.37A 5tzoC-3cmuA:
undetectable		 5tzoC-3cmuA:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 SER A3185
VAL A3138
ALA A4009
ALA A3137
GLY A3136
 None
 1.36A 5tzoC-3cmuA:
undetectable		 5tzoC-3cmuA:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 SER A4185
VAL A4138
ALA A5009
ALA A4137
GLY A4136
 None
 1.34A 5tzoC-3cmuA:
undetectable		 5tzoC-3cmuA:
5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A 126
PHE A 191
ILE A  93
ALA A  91
GLY A  59
 None
 1.02A 5veuA-3cmuA:
undetectable		 5veuA-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A1126
PHE A1191
ILE A1093
ALA A1091
GLY A1059
 None
 1.02A 5veuA-3cmuA:
undetectable		 5veuA-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A2126
PHE A2191
ILE A2093
ALA A2091
GLY A2059
 None
 1.02A 5veuA-3cmuA:
undetectable		 5veuA-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A3126
PHE A3191
ILE A3093
ALA A3091
GLY A3059
 None
 1.02A 5veuA-3cmuA:
undetectable		 5veuA-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A4126
PHE A4191
ILE A4093
ALA A4091
GLY A4059
 None
 1.02A 5veuA-3cmuA:
undetectable		 5veuA-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A5126
PHE A5191
ILE A5093
ALA A5091
GLY A5059
 None
 1.03A 5veuA-3cmuA:
undetectable		 5veuA-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A 126
PHE A 191
ILE A  93
ALA A  91
GLY A  59
 None
 1.02A 5veuH-3cmuA:
undetectable		 5veuH-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A1126
PHE A1191
ILE A1093
ALA A1091
GLY A1059
 None
 1.02A 5veuH-3cmuA:
undetectable		 5veuH-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A2126
PHE A2191
ILE A2093
ALA A2091
GLY A2059
 None
 1.02A 5veuH-3cmuA:
undetectable		 5veuH-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A3126
PHE A3191
ILE A3093
ALA A3091
GLY A3059
 None
 1.03A 5veuH-3cmuA:
undetectable		 5veuH-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A4126
PHE A4191
ILE A4093
ALA A4091
GLY A4059
 None
 1.02A 5veuH-3cmuA:
undetectable		 5veuH-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 3cmu PROTEIN RECA
(Escherichia
coli) 		5 / 12 LEU A5126
PHE A5191
ILE A5093
ALA A5091
GLY A5059
 None
 1.03A 5veuH-3cmuA:
undetectable		 5veuH-3cmuA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 GLU A 320
LYS A 322
GLU A 318
ALA A 316
 None
 1.18A 6an0A-3cmuA:
undetectable		 6an0A-3cmuA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 GLU A1320
LYS A1322
GLU A1318
ALA A1316
 None
 1.21A 6an0A-3cmuA:
undetectable		 6an0A-3cmuA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 GLU A2320
LYS A2322
GLU A2318
ALA A2316
 None
 1.19A 6an0A-3cmuA:
undetectable		 6an0A-3cmuA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 GLU A3320
LYS A3322
GLU A3318
ALA A3316
 None
 1.19A 6an0A-3cmuA:
undetectable		 6an0A-3cmuA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 GLU A4320
LYS A4322
GLU A4318
ALA A4316
 None
 1.19A 6an0A-3cmuA:
undetectable		 6an0A-3cmuA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 6 GLU A5320
LYS A5322
GLU A5318
ALA A5316
 None
 1.19A 6an0A-3cmuA:
undetectable		 6an0A-3cmuA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 5 ILE A  93
SER A 117
ALA A 131
LEU A 178
 None
 0.98A 6dwnA-3cmuA:
undetectable		 6dwnA-3cmuA:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 5 ILE A1093
SER A1117
ALA A1131
LEU A1178
 None
 0.97A 6dwnA-3cmuA:
undetectable		 6dwnA-3cmuA:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 5 ILE A2093
SER A2117
ALA A2131
LEU A2178
 None
 0.97A 6dwnA-3cmuA:
undetectable		 6dwnA-3cmuA:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 5 ILE A3093
SER A3117
ALA A3131
LEU A3178
 None
 0.97A 6dwnA-3cmuA:
undetectable		 6dwnA-3cmuA:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 5 ILE A4093
SER A4117
ALA A4131
LEU A4178
 None
 0.97A 6dwnA-3cmuA:
undetectable		 6dwnA-3cmuA:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3cmu PROTEIN RECA
(Escherichia
coli) 		4 / 5 ILE A5093
SER A5117
ALA A5131
LEU A5178
 None
 0.97A 6dwnA-3cmuA:
undetectable		 6dwnA-3cmuA:
3.47