SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  40
VAL A  39
LEU A 159
LEU A 135
 None
 0.87A 1cqpA-3cn7A:
4.2
1cqpB-3cn7A:
4.9		 1cqpA-3cn7A:
21.10
1cqpB-3cn7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  45
THR A  43
LEU A 135
VAL A  39
 None
 0.82A 1t86A-3cn7A:
undetectable		 1t86A-3cn7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A  23
GLY A  21
LEU A  19
GLY A 111
TYR A 140
PRO A 142
 None
 1.19A 1y4lA-3cn7A:
undetectable		 1y4lA-3cn7A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 7 PHE A  45
THR A  43
LEU A 135
VAL A  39
 None
 0.82A 2cppA-3cn7A:
undetectable		 2cppA-3cn7A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		3 / 3 SER A  65
HIS A 121
ASP A 145
 None
 0.67A 2oxtA-3cn7A:
2.2		 2oxtA-3cn7A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 116
GLY A 133
PHE A 124
PHE A 144
 None
 0.95A 2qwxA-3cn7A:
3.1
2qwxB-3cn7A:
undetectable		 2qwxA-3cn7A:
21.58
2qwxB-3cn7A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  39
GLY A 208
ILE A 108
THR A  43
LEU A 215
 None
 1.29A 3bexC-3cn7A:
undetectable
3bexD-3cn7A:
undetectable		 3bexC-3cn7A:
21.59
3bexD-3cn7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A  43
LEU A 215
VAL A  39
GLY A 208
ILE A 108
 None
 1.29A 3bexE-3cn7A:
undetectable
3bexF-3cn7A:
undetectable		 3bexE-3cn7A:
21.59
3bexF-3cn7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A  43
LEU A 215
VAL A  39
GLY A 208
ILE A 108
 None
 1.35A 3bf1C-3cn7A:
undetectable
3bf1D-3cn7A:
undetectable		 3bf1C-3cn7A:
21.59
3bf1D-3cn7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 11 VAL A  39
GLY A 208
ILE A 108
THR A  43
LEU A 215
 None
 1.30A 3bf1E-3cn7A:
undetectable
3bf1F-3cn7A:
undetectable		 3bf1E-3cn7A:
21.59
3bf1F-3cn7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A  43
LEU A 215
VAL A  39
GLY A 208
ILE A 108
 None
 1.33A 3bf1E-3cn7A:
undetectable
3bf1F-3cn7A:
undetectable		 3bf1E-3cn7A:
21.59
3bf1F-3cn7A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 7 LEU A  40
SER A  42
ARG A  44
ILE A  16
PHE A  45
 None
 1.48A 3ln1B-3cn7A:
undetectable		 3ln1B-3cn7A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 124
ALA A 141
PHE A 144
ALA A 136
 None
 0.88A 3t3sD-3cn7A:
undetectable		 3t3sD-3cn7A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 9 ALA A  50
LEU A  93
LEU A  19
LEU A  47
ILE A  17
 None
 1.20A 3wdmC-3cn7A:
undetectable		 3wdmC-3cn7A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 7 PHE A  45
THR A  43
LEU A 135
VAL A  39
 None
 0.81A 4cp4A-3cn7A:
undetectable		 4cp4A-3cn7A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  45
THR A  43
LEU A 135
VAL A  39
 None
 0.84A 4l4aA-3cn7A:
undetectable		 4l4aA-3cn7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  45
THR A  43
LEU A 135
VAL A  39
 None
 0.88A 4l4dA-3cn7A:
undetectable		 4l4dA-3cn7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  45
THR A  43
LEU A 135
VAL A  39
 None
 0.82A 4l4eA-3cn7A:
undetectable		 4l4eA-3cn7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  45
THR A  43
LEU A 135
VAL A  39
 None
 0.84A 4l4fA-3cn7A:
undetectable		 4l4fA-3cn7A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA301_1
(CHITOSANASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		4 / 4 ASP A  25
GLY A  23
PRO A  64
GLN A 114
 None
 1.39A 4oltA-3cn7A:
0.0		 4oltA-3cn7A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 208
HIS A 205
ASP A 206
ILE A 108
LEU A  36
 None
 1.32A 4pooA-3cn7A:
3.7		 4pooA-3cn7A:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 194
MET A 195
TYR A 193
 None
 0.95A 4qa0B-3cn7A:
2.6		 4qa0B-3cn7A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 194
MET A 195
TYR A 193
 None
 0.92A 4qa0A-3cn7A:
undetectable		 4qa0A-3cn7A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 194
MET A 195
TYR A 193
 None
 0.89A 4qa2B-3cn7A:
3.0		 4qa2B-3cn7A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		3 / 3 SER A  65
ASP A 145
ASP A  79
 None
 0.82A 4uckA-3cn7A:
undetectable		 4uckA-3cn7A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A 122
ALA A 123
GLY A 115
GLY A 116
ALA A 117
 None
 1.01A 5lf3K-3cn7A:
undetectable
5lf3L-3cn7A:
undetectable		 5lf3K-3cn7A:
24.14
5lf3L-3cn7A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3cn7 CARBOXYLESTERASE
(Pseudomonas
aeruginosa) 		5 / 11 THR A 122
ALA A 123
GLY A 115
GLY A 116
ALA A 117
 None
 1.02A 5lf3Y-3cn7A:
undetectable
5lf3Z-3cn7A:
undetectable		 5lf3Y-3cn7A:
24.14
5lf3Z-3cn7A:
23.65