SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cnb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3cnb DNA-BINDING RESPONSE
REGULATOR, MERR
FAMILY
(Colwellia
psychrerythraea) 		5 / 12 LEU A 117
CYH A 167
ALA A 146
PHE A 127
ASP A 154
 None
 0.98A 1bx4A-3cnbA:
5.5		 1bx4A-3cnbA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 3cnb DNA-BINDING RESPONSE
REGULATOR, MERR
FAMILY
(Colwellia
psychrerythraea) 		4 / 7 PHE A  66
SER A  67
ILE A 133
ILE A 142
 None
 0.97A 1sbrB-3cnbA:
undetectable		 1sbrB-3cnbA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3cnb DNA-BINDING RESPONSE
REGULATOR, MERR
FAMILY
(Colwellia
psychrerythraea) 		5 / 12 MET A 147
LEU A  81
LEU A 177
ILE A  96
LEU A 184
 None
 1.22A 2po5A-3cnbA:
5.7		 2po5A-3cnbA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3cnb DNA-BINDING RESPONSE
REGULATOR, MERR
FAMILY
(Colwellia
psychrerythraea) 		4 / 7 LEU A 177
LEU A 172
THR A 166
THR A 180
 None
 0.88A 4z90A-3cnbA:
undetectable
4z90B-3cnbA:
undetectable
4z90C-3cnbA:
undetectable
4z90D-3cnbA:
undetectable
4z90E-3cnbA:
undetectable		 4z90A-3cnbA:
17.59
4z90B-3cnbA:
17.59
4z90C-3cnbA:
17.59
4z90D-3cnbA:
17.59
4z90E-3cnbA:
17.59