SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cnc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 VAL A 303
VAL A 305
TRP A 324
 None
 0.99A 1av2A-3cncA:
undetectable
1av2B-3cncA:
undetectable		 1av2A-3cncA:
6.11
1av2B-3cncA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 LEU A 188
LEU A 186
ILE A 197
SER A 239
VAL A 305
 None
 1.12A 2hrcA-3cncA:
undetectable		 2hrcA-3cncA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 7 LEU A 186
LEU A 240
SER A 238
VAL A 305
 None
 0.95A 3d2tA-3cncA:
undetectable		 3d2tA-3cncA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 7 LEU A 186
LEU A 225
SER A 323
THR A 306
 None
 1.05A 3lm8A-3cncA:
undetectable
3lm8C-3cncA:
undetectable		 3lm8A-3cncA:
20.82
3lm8C-3cncA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 8 PHE A 227
TYR A 318
ASN A 308
GLU A 351
 None
 1.11A 3rqwC-3cncA:
undetectable
3rqwD-3cncA:
undetectable		 3rqwC-3cncA:
22.73
3rqwD-3cncA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 8 GLU A 351
PHE A 227
TYR A 318
ASN A 308
 None
 1.11A 3rqwF-3cncA:
undetectable
3rqwJ-3cncA:
undetectable		 3rqwF-3cncA:
22.73
3rqwJ-3cncA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 ASN A 172
ALA A 171
LYS A 185
 None
 0.93A 3runA-3cncA:
undetectable		 3runA-3cncA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 VAL A 305
PHE A 346
SER A 347
LEU A 190
VAL A 191
 None
 1.16A 4eckA-3cncA:
undetectable		 4eckA-3cncA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		3 / 3 ASP A 283
ASN A 321
SER A 266
 None
 0.83A 4obwA-3cncA:
undetectable		 4obwA-3cncA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 LEU A 225
MET A 252
LEU A 163
ASN A 245
GLY A 231
 None
 1.01A 4qckA-3cncA:
undetectable		 4qckA-3cncA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		5 / 12 LEU A 188
LEU A 190
LEU A 240
ALA A 260
MET A 264
 None
 1.12A 5og9B-3cncA:
undetectable		 5og9B-3cncA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3cnc FIBER PROTEIN
(Human
mastadenovirus
B) 		4 / 5 LEU A 213
THR A 210
THR A 338
GLY A 205
 None
 1.19A 6gtqA-3cncA:
undetectable		 6gtqA-3cncA:
24.44