SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3cng NUDIX HYDROLASE
(Nitrosomonas
europaea) 		5 / 10 ILE A  58
ALA A  59
ARG A  56
GLU A 129
ILE A 128
 None
None
None
NA  A 512 ( 4.2A)
None
 1.37A 2dm6A-3cngA:
undetectable
2dm6B-3cngA:
undetectable		 2dm6A-3cngA:
20.24
2dm6B-3cngA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 3cng NUDIX HYDROLASE
(Nitrosomonas
europaea) 		4 / 6 GLU A 129
ARG A  56
GLU A  89
GLU A  85
 NA  A 512 ( 4.2A)
None
None
NA  A 512 (-2.5A)
 1.42A 4kr3A-3cngA:
undetectable		 4kr3A-3cngA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 3cng NUDIX HYDROLASE
(Nitrosomonas
europaea) 		4 / 7 PRO A  45
VAL A  94
ALA A  92
PHE A 124
 None
 1.02A 4lb2A-3cngA:
undetectable		 4lb2A-3cngA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3cng NUDIX HYDROLASE
(Nitrosomonas
europaea) 		4 / 8 GLY A  81
GLY A  42
ILE A  40
LEU A 114
 None
None
GOL  A 501 (-4.8A)
None
 0.84A 4mwzB-3cngA:
undetectable		 4mwzB-3cngA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3cng NUDIX HYDROLASE
(Nitrosomonas
europaea) 		6 / 12 ILE A 146
ILE A  40
GLY A  70
ALA A  69
LEU A  67
LEU A  53
 None
GOL  A 501 (-4.8A)
NA  A 512 ( 4.2A)
None
None
None
 1.37A 4o1zA-3cngA:
undetectable		 4o1zA-3cngA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3cng NUDIX HYDROLASE
(Nitrosomonas
europaea) 		3 / 3 VAL A 150
LYS A 156
MET A 159
 CL  A 519 ( 3.9A)
None
None
 1.02A 5nknA-3cngA:
undetectable		 5nknA-3cngA:
17.86