SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cnn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermotoga
maritima) 		4 / 5 ARG A 213
ALA A 240
LYS A 239
GLU A 234
 None
 1.17A 1e7cA-3cnnA:
undetectable		 1e7cA-3cnnA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermotoga
maritima) 		4 / 5 LEU A 168
GLU A 246
ALA A 166
LEU A 174
 None
 1.20A 1eta1-3cnnA:
undetectable		 1eta1-3cnnA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermotoga
maritima) 		5 / 11 LEU A  90
THR A  81
GLY A  84
THR A 114
ILE A 115
 None
None
None
GTP  A 263 (-3.5A)
None
 1.28A 3bf1C-3cnnA:
undetectable
3bf1D-3cnnA:
undetectable		 3bf1C-3cnnA:
22.26
3bf1D-3cnnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermotoga
maritima) 		4 / 5 ASP A 250
ARG A 194
ILE A 191
VAL A 243
 None
 1.08A 3eigA-3cnnA:
2.2		 3eigA-3cnnA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermotoga
maritima) 		5 / 12 ASN A  54
THR A  24
ILE A  79
THR A  81
LEU A  94
 GTP  A 263 (-3.7A)
None
None
None
None
 1.11A 3iv6A-3cnnA:
undetectable		 3iv6A-3cnnA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermotoga
maritima) 		5 / 12 LEU A  18
VAL A  22
LEU A 119
ILE A 148
LEU A  52
 None
 1.12A 4y0qA-3cnnA:
undetectable		 4y0qA-3cnnA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermotoga
maritima) 		4 / 6 ARG A  29
ALA A  31
PRO A  34
PHE A  71
 None
 1.22A 5odqA-3cnnA:
undetectable		 5odqA-3cnnA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN
(Thermotoga
maritima) 		5 / 12 PHE A 185
ILE A 159
ALA A 165
LEU A 169
ALA A 188
 None
 1.30A 5oy02-3cnnA:
undetectable		 5oy02-3cnnA:
13.74