SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 12 THR A 168
ARG A 228
GLU A 171
GLY A 163
GLY A 165
 None
 1.20A 1httB-3cnyA:
undetectable		 1httB-3cnyA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 12 THR A 168
ARG A 228
GLU A 171
GLY A 163
GLY A 165
 None
 1.22A 1httD-3cnyA:
undetectable		 1httD-3cnyA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 12 ALA A 106
GLY A  72
ALA A 149
HIS A  94
PHE A  91
 None
None
None
EDO  A 302 ( 3.7A)
None
 1.04A 1ve3A-3cnyA:
undetectable		 1ve3A-3cnyA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 12 ALA A 106
GLY A  72
ALA A 149
HIS A  94
PHE A  91
 None
None
None
EDO  A 302 ( 3.7A)
None
 1.03A 1ve3B-3cnyA:
undetectable		 1ve3B-3cnyA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 6 ILE A  16
HIS A 159
HIS A 161
HIS A 192
 None
 0.87A 1y93A-3cnyA:
undetectable		 1y93A-3cnyA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 11 GLY A 165
ASP A 189
THR A 164
GLY A 163
HIS A 161
 None
 1.40A 2hmaA-3cnyA:
undetectable		 2hmaA-3cnyA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 9 THR A  47
PHE A  44
GLU A  48
GLY A  17
ILE A  16
 None
 1.38A 2w98A-3cnyA:
undetectable		 2w98A-3cnyA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 8 GLY A 249
ILE A 193
VAL A 214
TYR A 188
 None
 0.85A 2yoeB-3cnyA:
undetectable
2yoeC-3cnyA:
undetectable		 2yoeB-3cnyA:
22.28
2yoeC-3cnyA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 5 ILE A  16
HIS A 159
HIS A 161
HIS A 192
 None
 0.96A 3ljgA-3cnyA:
undetectable		 3ljgA-3cnyA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 5 THR A  47
ILE A  70
PHE A  53
LEU A  36
 None
 1.36A 3tf1A-3cnyA:
undetectable		 3tf1A-3cnyA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9W_A_VGHA1158_1
(7,8-DIHYDRO-8-OXOGUA
NINE TRIPHOSPHATASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 12 PHE A 243
MET A 242
VAL A 219
ASP A 189
PHE A 234
 None
 1.44A 4c9wA-3cnyA:
undetectable		 4c9wA-3cnyA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 8 SER A 109
GLN A 111
PHE A 243
ILE A  16
 None
 0.98A 4dx7B-3cnyA:
undetectable		 4dx7B-3cnyA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 8 MET A 285
ALA A 286
PHE A 216
THR A 190
 None
 0.90A 4ltwA-3cnyA:
undetectable		 4ltwA-3cnyA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 4 HIS A 192
GLU A  48
HIS A 213
LEU A 260
 None
 1.07A 4m2rA-3cnyA:
undetectable		 4m2rA-3cnyA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		3 / 3 SER A  76
TYR A  78
ASP A  22
 None
 0.81A 4rp8C-3cnyA:
undetectable		 4rp8C-3cnyA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 12 THR A 168
ARG A 228
GLU A 171
GLY A 163
GLY A 165
 None
 1.24A 5e3iA-3cnyA:
undetectable		 5e3iA-3cnyA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 11 THR A 168
ARG A 228
GLU A 171
GLY A 163
GLY A 165
 None
 1.26A 5e3iB-3cnyA:
undetectable		 5e3iB-3cnyA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 8 GLU A  48
HIS A 159
VAL A 107
ASP A 189
HIS A 192
 None
 1.36A 5f8yA-3cnyA:
undetectable		 5f8yA-3cnyA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 8 GLU A  48
HIS A 159
VAL A 107
ASP A 189
HIS A 192
 None
 1.34A 5f8yB-3cnyA:
undetectable		 5f8yB-3cnyA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 5 ILE A  16
HIS A 159
HIS A 161
HIS A 192
 None
 0.90A 5n5kA-3cnyA:
undetectable		 5n5kA-3cnyA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 11 LEU A 251
GLY A 249
GLY A 247
VAL A 271
THR A 244
 None
 1.04A 5o96G-3cnyA:
undetectable		 5o96G-3cnyA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 10 LEU A 251
GLY A 249
GLY A 247
VAL A 271
THR A 244
 None
 0.98A 5o96G-3cnyA:
undetectable
5o96H-3cnyA:
undetectable		 5o96G-3cnyA:
23.28
5o96H-3cnyA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		5 / 12 ILE A 166
PHE A  91
LEU A 183
THR A 179
LEU A 175
 None
 1.23A 5xxiA-3cnyA:
undetectable		 5xxiA-3cnyA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 5 HIS A 192
GLU A  48
HIS A 213
LEU A 260
 None
 1.06A 6bc9A-3cnyA:
undetectable		 6bc9A-3cnyA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3cny INOSITOL CATABOLISM
PROTEIN IOLE
(Lactobacillus
plantarum) 		4 / 8 ASP A  21
ARG A  19
GLU A 272
GLN A  45
 None
 0.98A 6fbvD-3cnyA:
undetectable		 6fbvD-3cnyA:
13.48