SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3co5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ID5_B_SAMB301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	3co5	PUTATIVE TWO-COMPONENT SYSTEM TRANSCRIPTIONAL RESPONSE REGULATOR (Neisseria gonorrhoeae)	5 / 11	TYR A 209 GLY A 211 ASP A 212 ILE A 213 GLN A 221	None	1.34A	3id5B-3co5A: undetectable	3id5B-3co5A: 23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ID5_F_SAMF301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	3co5	PUTATIVE TWO-COMPONENT SYSTEM TRANSCRIPTIONAL RESPONSE REGULATOR (Neisseria gonorrhoeae)	5 / 11	TYR A 209 GLY A 211 ASP A 212 ILE A 213 GLN A 221	None	1.34A	3id5F-3co5A: undetectable	3id5F-3co5A: 23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M6T_A_SAMA201_0 (RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG, LINKER, RNA POLYMERASE-ASSOCIATE D PROTEIN LEO1)	3co5	PUTATIVE TWO-COMPONENT SYSTEM TRANSCRIPTIONAL RESPONSE REGULATOR (Neisseria gonorrhoeae)	4 / 4	ILE A 239 VAL A 184 VAL A 207 ARG A 237	None	1.33A	4m6tA-3co5A: undetectable	4m6tA-3co5A: 22.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ID5_B_SAMB301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","3co5","PUTATIVE TWO-COMPONENT SYSTEM TRANSCRIPTIONAL RESPONSE REGULATOR","Neisseria gonorrhoeae",5,"TYR A 209;GLY A 211;ASP A 212;ILE A 213;GLN A 221","None","1.34A","3id5B-3co5A:undetectable","3id5B-3co5A:23.71"],["3ID5_F_SAMF301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","3co5","PUTATIVE TWO-COMPONENT SYSTEM TRANSCRIPTIONAL RESPONSE REGULATOR","Neisseria gonorrhoeae",5,"TYR A 209;GLY A 211;ASP A 212;ILE A 213;GLN A 221","None","1.34A","3id5F-3co5A:undetectable","3id5F-3co5A:23.71"],["4M6T_A_SAMA201_0","RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG, LINKER, RNA POLYMERASE-ASSOCIATED PROTEIN LEO1","3co5","PUTATIVE TWO-COMPONENT SYSTEM TRANSCRIPTIONAL RESPONSE REGULATOR","Neisseria gonorrhoeae",4,"ILE A 239;VAL A 184;VAL A 207;ARG A 237","None","1.33A","4m6tA-3co5A:undetectable","4m6tA-3co5A:22.05"]]