SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3coi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DRE_A_MTXA161_1 (DIHYDROFOLATE REDUCTASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 12	ALA A 302 MET A 288 LEU A 138 ILE A 212 LEU A 156	None	1.24A	1dreA-3coiA: undetectable	1dreA-3coiA: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IHI_A_IU5A326_1 (3-ALPHA-HYDROXYSTERO ID DEHYDROGENASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 10	TYR A 132 VAL A 131 VAL A 209 ILE A 206 GLU A 317	None	1.31A	1ihiA-3coiA: undetectable	1ihiA-3coiA: 22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IHI_B_IU5B327_1 (3-ALPHA-HYDROXYSTERO ID DEHYDROGENASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 9	TYR A 132 VAL A 131 VAL A 209 ILE A 206 GLU A 317	None	1.31A	1ihiB-3coiA: 0.0	1ihiB-3coiA: 22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_E_BEZE509_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 7	ILE A 127 GLU A 124 PHE A 274 ALA A 277	None	1.01A	1oniD-3coiA: undetectable 1oniE-3coiA: undetectable	1oniD-3coiA: 18.36 1oniE-3coiA: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OS6_A_DXCA75_0 (PPCA)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 8	ILE A 166 LEU A 156 MET A 213 GLY A 210	None	0.74A	1os6A-3coiA: undetectable	1os6A-3coiA: 12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XKK_A_FMMA91_2 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 9	VAL A 39 LYS A 54 LEU A 87 LEU A 105 MET A 110	None	0.75A	1xkkA-3coiA: 19.1	1xkkA-3coiA: 26.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J9D_A_ACTA1117_0 (HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	3 / 3	ASP A 150 ARG A 149 ARG A 189	None	1.08A	2j9dA-3coiA: undetectable 2j9dC-3coiA: undetectable	2j9dA-3coiA: 18.65 2j9dC-3coiA: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QX4_B_ML1B233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 7	GLY A 240 THR A 265 PHE A 270 PHE A 274	None	1.11A	2qx4A-3coiA: undetectable 2qx4B-3coiA: undetectable	2qx4A-3coiA: 22.71 2qx4B-3coiA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1375_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	3 / 3	LEU A 229 TYR A 228 GLN A 231	None	0.70A	2wekA-3coiA: undetectable	2wekA-3coiA: 23.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GCS_A_BAXA401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 12	VAL A 39 ALA A 52 GLU A 72 LEU A 76 HIS A 148 LEU A 167	None	0.95A	3gcsA-3coiA: 38.3	3gcsA-3coiA: 61.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GCS_A_BAXA401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	7 / 12	VAL A 39 ALA A 52 LEU A 75 LEU A 76 ILE A 141 HIS A 148 LEU A 167	None	0.92A	3gcsA-3coiA: 38.3	3gcsA-3coiA: 61.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GCS_A_BAXA401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	7 / 12	VAL A 39 ALA A 52 LEU A 76 ILE A 85 ILE A 141 HIS A 148 LEU A 167	None	0.88A	3gcsA-3coiA: 38.3	3gcsA-3coiA: 61.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GP0_A_NILA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	9 / 12	VAL A 39 ALA A 52 GLU A 72 LEU A 75 LEU A 76 ILE A 85 HIS A 148 ALA A 157 LEU A 167	None	0.80A	3gp0A-3coiA: 36.5	3gp0A-3coiA: 60.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GP0_A_NILA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 12	VAL A 39 GLU A 72 LEU A 75 LEU A 76 HIS A 148 ASP A 168	None	1.08A	3gp0A-3coiA: 36.5	3gp0A-3coiA: 60.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GP0_A_NILA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 7	LYS A 54 VAL A 84 LEU A 105 ILE A 166	None	0.60A	3gp0A-3coiA: 36.5	3gp0A-3coiA: 60.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3GP0_A_NILA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 7	VAL A 84 LEU A 105 MET A 110 ILE A 166	None	0.60A	3gp0A-3coiA: 36.5	3gp0A-3coiA: 60.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HEC_A_STIA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 12	GLU A 72 LEU A 75 LEU A 76 ILE A 85 ASP A 168	None	0.95A	3hecA-3coiA: 37.7	3hecA-3coiA: 61.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HEC_A_STIA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	7 / 12	VAL A 31 ALA A 52 GLU A 72 LEU A 75 LEU A 76 ILE A 85 LEU A 167	None	0.68A	3hecA-3coiA: 37.7	3hecA-3coiA: 61.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HEG_A_BAXA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 12	VAL A 31 VAL A 39 ALA A 52 GLU A 72 LEU A 76 ILE A 141	None	0.76A	3hegA-3coiA: 37.5	3hegA-3coiA: 61.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HEG_A_BAXA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 12	VAL A 31 VAL A 39 ALA A 52 LEU A 75 LEU A 76 ILE A 141	None	0.71A	3hegA-3coiA: 37.5	3hegA-3coiA: 61.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HEG_A_BAXA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 12	VAL A 31 VAL A 39 ALA A 52 LEU A 76 ILE A 85 ILE A 141	None	0.55A	3hegA-3coiA: 37.5	3hegA-3coiA: 61.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HEG_A_BAXA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 6	VAL A 84 HIS A 148 ILE A 166 LEU A 167	None	0.60A	3hegA-3coiA: 37.5	3hegA-3coiA: 61.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3LFA_A_1N1A361_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 8	VAL A 31 ALA A 52 GLU A 72 LEU A 105 MET A 110	None	0.56A	3lfaA-3coiA: 38.8	3lfaA-3coiA: 61.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OHT_A_1N1A1000_1 (P38A)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	7 / 12	VAL A 31 GLY A 32 VAL A 39 ALA A 52 LEU A 76 ILE A 85 LEU A 167	None	0.44A	3ohtA-3coiA: 32.5	3ohtA-3coiA: 58.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OHT_B_1N1B1000_1 (P38A)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 12	GLY A 32 VAL A 39 ALA A 52 LEU A 76 ILE A 85 LEU A 167	None	0.43A	3ohtB-3coiA: 32.6	3ohtB-3coiA: 58.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_B_SAMB300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	3 / 3	TYR A 36 ASP A 168 ASP A 113	None	0.79A	3ou6B-3coiA: undetectable	3ou6B-3coiA: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SEL_X_DXCX75_0 (CYTOCHROME C7)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 8	ILE A 166 LEU A 156 MET A 213 GLY A 210	None	0.78A	3selX-3coiA: undetectable	3selX-3coiA: 12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SJ1_X_DXCX75_0 (CYTOCHROME C7)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 6	ILE A 166 LEU A 156 MET A 213 GLY A 210	None	0.80A	3sj1X-3coiA: undetectable	3sj1X-3coiA: 13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRI_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 5	LEU A 171 GLY A 170 ILE A 85 VAL A 84	None	0.92A	3wriA-3coiA: undetectable	3wriA-3coiA: 21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRI_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 5	LEU A 171 GLY A 170 ILE A 85 VAL A 84	None	0.90A	3wriB-3coiA: undetectable	3wriB-3coiA: 21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AN2_A_EUIA1382_1 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 12	ASP A 150 LYS A 152 ASN A 155 ASP A 168 GLY A 170	None	0.73A	4an2A-3coiA: 20.5	4an2A-3coiA: 27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HAJ_A_DXCA75_0 (PPCA)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 7	ILE A 166 LEU A 156 MET A 213 GLY A 210	None	0.80A	4hajA-3coiA: undetectable	4hajA-3coiA: 12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HC3_A_DXCA75_0 (PPCA)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 7	ILE A 166 LEU A 156 MET A 213 GLY A 210	None	0.74A	4hc3A-3coiA: undetectable	4hc3A-3coiA: 11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IFG_A_1E8A601_1 (CALMODULIN-DOMAIN PROTEIN KINASE 1)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 12	GLY A 32 VAL A 39 ALA A 52 LYS A 54 LEU A 87 LEU A 105	None	0.50A	4ifgA-3coiA: 20.8	4ifgA-3coiA: 25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_A_8PRA601_1 (RHODOPSIN KINASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 7	VAL A 39 ALA A 52 LEU A 56 MET A 107 LEU A 167	None	1.27A	4l9iA-3coiA: 8.2	4l9iA-3coiA: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_A_8PRA601_1 (RHODOPSIN KINASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 7	VAL A 39 ALA A 52 MET A 107 MET A 110 ASP A 113	None	0.81A	4l9iA-3coiA: 8.2	4l9iA-3coiA: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_B_8PRB601_1 (RHODOPSIN KINASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 8	GLY A 34 ALA A 52 LYS A 54 MET A 107 LEU A 167	None	1.49A	4l9iB-3coiA: 21.5	4l9iB-3coiA: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_B_8PRB601_1 (RHODOPSIN KINASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 8	GLY A 34 ALA A 52 LYS A 54 MET A 107 MET A 110 ASP A 113	None	1.09A	4l9iB-3coiA: 21.5	4l9iB-3coiA: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_B_8PRB601_1 (RHODOPSIN KINASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 8	GLY A 34 VAL A 39 ALA A 52 MET A 107 LEU A 167	None	1.16A	4l9iB-3coiA: 21.5	4l9iB-3coiA: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9I_B_8PRB601_1 (RHODOPSIN KINASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 8	GLY A 34 VAL A 39 ALA A 52 MET A 107 MET A 110 ASP A 113	None	0.84A	4l9iB-3coiA: 21.5	4l9iB-3coiA: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZDY_A_1YNA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	3 / 3	ALA A 255 TYR A 258 PRO A 191	None	0.51A	4zdyA-3coiA: undetectable	4zdyA-3coiA: 21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZJ_F_AZ1F2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAR-DAR-DAR)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	5 / 7	GLY A 32 GLY A 34 GLY A 37 VAL A 39 LEU A 56	None	0.81A	5izjB-3coiA: 22.6	5izjB-3coiA: 27.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_B_ADNB401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 9	GLY A 32 VAL A 39 ALA A 52 ILE A 85 MET A 107 MET A 110	None	0.67A	5lw1B-3coiA: 36.0	5lw1B-3coiA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_B_ADNB401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 9	VAL A 39 ALA A 52 ILE A 85 MET A 107 MET A 110 LEU A 167	None	0.82A	5lw1B-3coiA: 36.0	5lw1B-3coiA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_E_ADNE401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 10	GLY A 32 VAL A 39 ALA A 52 ILE A 85 MET A 107 MET A 110	None	0.66A	5lw1E-3coiA: 35.9	5lw1E-3coiA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_E_ADNE401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 10	VAL A 39 ALA A 52 ILE A 85 MET A 107 MET A 110 LEU A 167	None	0.80A	5lw1E-3coiA: 35.9	5lw1E-3coiA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LW1_H_ADNH401_1 (MITOGEN-ACTIVATED PROTEIN KINASE 8)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	6 / 9	GLY A 32 VAL A 39 ALA A 52 MET A 107 MET A 110 LEU A 167	None	0.78A	5lw1H-3coiA: 36.1	5lw1H-3coiA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M66_A_ADNA502_2 (ADENOSYLHOMOCYSTEINA SE)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 4	GLN A 272 THR A 239 GLU A 286 LEU A 217	None	1.31A	5m66A-3coiA: undetectable	5m66A-3coiA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5V0V_A_8QSA615_1 (SERUM ALBUMIN)	3coi	MITOGEN-ACTIVATED PROTEIN KINASE 13 (Homo sapiens)	4 / 8	LEU A 167 VAL A 84 LEU A 151 ILE A 141	None	0.89A	5v0vA-3coiA: undetectable	5v0vA-3coiA: 19.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DRE_A_MTXA161_1","DIHYDROFOLATE REDUCTASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"ALA A 302;MET A 288;LEU A 138;ILE A 212;LEU A 156","None","1.24A","1dreA-3coiA:undetectable","1dreA-3coiA:18.98"],["1IHI_A_IU5A326_1","3-ALPHA-HYDROXYSTEROID DEHYDROGENASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"TYR A 132;VAL A 131;VAL A 209;ILE A 206;GLU A 317","None","1.31A","1ihiA-3coiA:undetectable","1ihiA-3coiA:22.82"],["1IHI_B_IU5B327_1","3-ALPHA-HYDROXYSTEROID DEHYDROGENASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"TYR A 132;VAL A 131;VAL A 209;ILE A 206;GLU A 317","None","1.31A","1ihiB-3coiA:0.0","1ihiB-3coiA:22.82"],["1ONI_E_BEZE509_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"ILE A 127;GLU A 124;PHE A 274;ALA A 277","None","1.01A","1oniD-3coiA:undetectable;1oniE-3coiA:undetectable","1oniD-3coiA:18.36;1oniE-3coiA:18.36"],["1OS6_A_DXCA75_0","PPCA","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"ILE A 166;LEU A 156;MET A 213;GLY A 210","None","0.74A","1os6A-3coiA:undetectable","1os6A-3coiA:12.37"],["1XKK_A_FMMA91_2","EPIDERMAL GROWTH FACTOR RECEPTOR","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"VAL A  39;LYS A  54;LEU A  87;LEU A 105;MET A 110","None","0.75A","1xkkA-3coiA:19.1","1xkkA-3coiA:26.48"],["2J9D_A_ACTA1117_0","HYPOTHETICAL NITROGEN REGULATORY PII-LIKE PROTEIN MJ0059","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",3,"ASP A 150;ARG A 149;ARG A 189","None","1.08A","2j9dA-3coiA:undetectable;2j9dC-3coiA:undetectable","2j9dA-3coiA:18.65;2j9dC-3coiA:18.65"],["2QX4_B_ML1B233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"GLY A 240;THR A 265;PHE A 270;PHE A 274","None","1.11A","2qx4A-3coiA:undetectable;2qx4B-3coiA:undetectable","2qx4A-3coiA:22.71;2qx4B-3coiA:22.71"],["2WEK_A_DIFA1375_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",3,"LEU A 229;TYR A 228;GLN A 231","None","0.70A","2wekA-3coiA:undetectable","2wekA-3coiA:23.10"],["3GCS_A_BAXA401_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"VAL A  39;ALA A  52;GLU A  72;LEU A  76;HIS A 148;LEU A 167","None","0.95A","3gcsA-3coiA:38.3","3gcsA-3coiA:61.02"],["3GCS_A_BAXA401_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",7,"VAL A  39;ALA A  52;LEU A  75;LEU A  76;ILE A 141;HIS A 148;LEU A 167","None","0.92A","3gcsA-3coiA:38.3","3gcsA-3coiA:61.02"],["3GCS_A_BAXA401_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",7,"VAL A  39;ALA A  52;LEU A  76;ILE A  85;ILE A 141;HIS A 148;LEU A 167","None","0.88A","3gcsA-3coiA:38.3","3gcsA-3coiA:61.02"],["3GP0_A_NILA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 11","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",9,"VAL A  39;ALA A  52;GLU A  72;LEU A  75;LEU A  76;ILE A  85;HIS A 148;ALA A 157;LEU A 167","None","0.80A","3gp0A-3coiA:36.5","3gp0A-3coiA:60.06"],["3GP0_A_NILA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 11","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"VAL A  39;GLU A  72;LEU A  75;LEU A  76;HIS A 148;ASP A 168","None","1.08A","3gp0A-3coiA:36.5","3gp0A-3coiA:60.06"],["3GP0_A_NILA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 11","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"LYS A  54;VAL A  84;LEU A 105;ILE A 166","None","0.60A","3gp0A-3coiA:36.5","3gp0A-3coiA:60.06"],["3GP0_A_NILA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 11","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"VAL A  84;LEU A 105;MET A 110;ILE A 166","None","0.60A","3gp0A-3coiA:36.5","3gp0A-3coiA:60.06"],["3HEC_A_STIA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"GLU A  72;LEU A  75;LEU A  76;ILE A  85;ASP A 168","None","0.95A","3hecA-3coiA:37.7","3hecA-3coiA:61.89"],["3HEC_A_STIA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",7,"VAL A  31;ALA A  52;GLU A  72;LEU A  75;LEU A  76;ILE A  85;LEU A 167","None","0.68A","3hecA-3coiA:37.7","3hecA-3coiA:61.89"],["3HEG_A_BAXA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"VAL A  31;VAL A  39;ALA A  52;GLU A  72;LEU A  76;ILE A 141","None","0.76A","3hegA-3coiA:37.5","3hegA-3coiA:61.89"],["3HEG_A_BAXA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"VAL A  31;VAL A  39;ALA A  52;LEU A  75;LEU A  76;ILE A 141","None","0.71A","3hegA-3coiA:37.5","3hegA-3coiA:61.89"],["3HEG_A_BAXA1_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"VAL A  31;VAL A  39;ALA A  52;LEU A  76;ILE A  85;ILE A 141","None","0.55A","3hegA-3coiA:37.5","3hegA-3coiA:61.89"],["3HEG_A_BAXA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"VAL A  84;HIS A 148;ILE A 166;LEU A 167","None","0.60A","3hegA-3coiA:37.5","3hegA-3coiA:61.89"],["3LFA_A_1N1A361_1","MITOGEN-ACTIVATED PROTEIN KINASE 14","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"VAL A  31;ALA A  52;GLU A  72;LEU A 105;MET A 110","None","0.56A","3lfaA-3coiA:38.8","3lfaA-3coiA:61.30"],["3OHT_A_1N1A1000_1","P38A","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",7,"VAL A  31;GLY A  32;VAL A  39;ALA A  52;LEU A  76;ILE A  85;LEU A 167","None","0.44A","3ohtA-3coiA:32.5","3ohtA-3coiA:58.11"],["3OHT_B_1N1B1000_1","P38A","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"GLY A  32;VAL A  39;ALA A  52;LEU A  76;ILE A  85;LEU A 167","None","0.43A","3ohtB-3coiA:32.6","3ohtB-3coiA:58.11"],["3OU6_B_SAMB300_1","SAM-DEPENDENT METHYLTRANSFERASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",3,"TYR A  36;ASP A 168;ASP A 113","None","0.79A","3ou6B-3coiA:undetectable","3ou6B-3coiA:20.68"],["3SEL_X_DXCX75_0","CYTOCHROME C7","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"ILE A 166;LEU A 156;MET A 213;GLY A 210","None","0.78A","3selX-3coiA:undetectable","3selX-3coiA:12.37"],["3SJ1_X_DXCX75_0","CYTOCHROME C7","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"ILE A 166;LEU A 156;MET A 213;GLY A 210","None","0.80A","3sj1X-3coiA:undetectable","3sj1X-3coiA:13.06"],["3WRI_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"LEU A 171;GLY A 170;ILE A  85;VAL A  84","None","0.92A","3wriA-3coiA:undetectable","3wriA-3coiA:21.28"],["3WRI_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"LEU A 171;GLY A 170;ILE A  85;VAL A  84","None","0.90A","3wriB-3coiA:undetectable","3wriB-3coiA:21.28"],["4AN2_A_EUIA1382_1","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"ASP A 150;LYS A 152;ASN A 155;ASP A 168;GLY A 170","None","0.73A","4an2A-3coiA:20.5","4an2A-3coiA:27.22"],["4HAJ_A_DXCA75_0","PPCA","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"ILE A 166;LEU A 156;MET A 213;GLY A 210","None","0.80A","4hajA-3coiA:undetectable","4hajA-3coiA:12.37"],["4HC3_A_DXCA75_0","PPCA","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"ILE A 166;LEU A 156;MET A 213;GLY A 210","None","0.74A","4hc3A-3coiA:undetectable","4hc3A-3coiA:11.34"],["4IFG_A_1E8A601_1","CALMODULIN-DOMAIN PROTEIN KINASE 1","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"GLY A  32;VAL A  39;ALA A  52;LYS A  54;LEU A  87;LEU A 105","None","0.50A","4ifgA-3coiA:20.8","4ifgA-3coiA:25.62"],["4L9I_A_8PRA601_1","RHODOPSIN KINASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"VAL A  39;ALA A  52;LEU A  56;MET A 107;LEU A 167","None","1.27A","4l9iA-3coiA:8.2","4l9iA-3coiA:22.16"],["4L9I_A_8PRA601_1","RHODOPSIN KINASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"VAL A  39;ALA A  52;MET A 107;MET A 110;ASP A 113","None","0.81A","4l9iA-3coiA:8.2","4l9iA-3coiA:22.16"],["4L9I_B_8PRB601_1","RHODOPSIN KINASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"GLY A  34;ALA A  52;LYS A  54;MET A 107;LEU A 167","None","1.49A","4l9iB-3coiA:21.5","4l9iB-3coiA:22.16"],["4L9I_B_8PRB601_1","RHODOPSIN KINASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"GLY A  34;ALA A  52;LYS A  54;MET A 107;MET A 110;ASP A 113","None","1.09A","4l9iB-3coiA:21.5","4l9iB-3coiA:22.16"],["4L9I_B_8PRB601_1","RHODOPSIN KINASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"GLY A  34;VAL A  39;ALA A  52;MET A 107;LEU A 167","None","1.16A","4l9iB-3coiA:21.5","4l9iB-3coiA:22.16"],["4L9I_B_8PRB601_1","RHODOPSIN KINASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"GLY A  34;VAL A  39;ALA A  52;MET A 107;MET A 110;ASP A 113","None","0.84A","4l9iB-3coiA:21.5","4l9iB-3coiA:22.16"],["4ZDY_A_1YNA602_2","LANOSTEROL 14-ALPHA DEMETHYLASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",3,"ALA A 255;TYR A 258;PRO A 191","None","0.51A","4zdyA-3coiA:undetectable","4zdyA-3coiA:21.18"],["5IZJ_F_AZ1F2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAR-DAR-DAR","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",5,"GLY A  32;GLY A  34;GLY A  37;VAL A  39;LEU A  56","None","0.81A","5izjB-3coiA:22.6","5izjB-3coiA:27.13"],["5LW1_B_ADNB401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"GLY A  32;VAL A  39;ALA A  52;ILE A  85;MET A 107;MET A 110","None","0.67A","5lw1B-3coiA:36.0","5lw1B-3coiA:11.93"],["5LW1_B_ADNB401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"VAL A  39;ALA A  52;ILE A  85;MET A 107;MET A 110;LEU A 167","None","0.82A","5lw1B-3coiA:36.0","5lw1B-3coiA:11.93"],["5LW1_E_ADNE401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"GLY A  32;VAL A  39;ALA A  52;ILE A  85;MET A 107;MET A 110","None","0.66A","5lw1E-3coiA:35.9","5lw1E-3coiA:11.93"],["5LW1_E_ADNE401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"VAL A  39;ALA A  52;ILE A  85;MET A 107;MET A 110;LEU A 167","None","0.80A","5lw1E-3coiA:35.9","5lw1E-3coiA:11.93"],["5LW1_H_ADNH401_1","MITOGEN-ACTIVATED PROTEIN KINASE 8","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",6,"GLY A  32;VAL A  39;ALA A  52;MET A 107;MET A 110;LEU A 167","None","0.78A","5lw1H-3coiA:36.1","5lw1H-3coiA:11.93"],["5M66_A_ADNA502_2","ADENOSYLHOMOCYSTEINASE","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"GLN A 272;THR A 239;GLU A 286;LEU A 217","None","1.31A","5m66A-3coiA:undetectable","5m66A-3coiA:21.56"],["5V0V_A_8QSA615_1","SERUM ALBUMIN","3coi","MITOGEN-ACTIVATED PROTEIN KINASE 13","Homo sapiens",4,"LEU A 167;VAL A  84;LEU A 151;ILE A 141","None","0.89A","5v0vA-3coiA:undetectable","5v0vA-3coiA:19.10"]]