SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3col'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3col PUTATIVE
TRANSCRIPTION
REGULATOR
(Lactobacillus
plantarum) 		3 / 3 GLN A  92
ILE A 144
HIS A 152
 None
 0.66A 1fm9A-3colA:
undetectable		 1fm9A-3colA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3col PUTATIVE
TRANSCRIPTION
REGULATOR
(Lactobacillus
plantarum) 		3 / 3 GLN A  92
ILE A 144
HIS A 152
 None
 0.62A 1k74A-3colA:
undetectable		 1k74A-3colA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3col PUTATIVE
TRANSCRIPTION
REGULATOR
(Lactobacillus
plantarum) 		4 / 6 ARG A  65
ILE A 107
THR A 164
ALA A  99
 None
 0.87A 1w0gA-3colA:
undetectable		 1w0gA-3colA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3col PUTATIVE
TRANSCRIPTION
REGULATOR
(Lactobacillus
plantarum) 		4 / 5 ILE A 182
TYR A 172
ARG A 171
THR A 165
 None
 1.23A 3abkN-3colA:
2.1
3abkW-3colA:
undetectable		 3abkN-3colA:
18.07
3abkW-3colA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3col PUTATIVE
TRANSCRIPTION
REGULATOR
(Lactobacillus
plantarum) 		4 / 8 ILE A 110
ASN A  50
VAL A  28
GLY A  27
 None
 0.84A 3em0B-3colA:
undetectable		 3em0B-3colA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3col PUTATIVE
TRANSCRIPTION
REGULATOR
(Lactobacillus
plantarum) 		5 / 12 GLY A  24
LEU A  21
VAL A  28
VAL A  16
VAL A  58
 None
 1.13A 5dpdA-3colA:
undetectable		 5dpdA-3colA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3col PUTATIVE
TRANSCRIPTION
REGULATOR
(Lactobacillus
plantarum) 		3 / 3 GLN A  92
ILE A 144
HIS A 152
 None
 0.67A 5z12B-3colA:
undetectable		 5z12B-3colA:
17.26