SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 3cou NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 16
(Homo
sapiens) 		4 / 8 PHE A  57
MET A  47
PHE A 158
LEU A 175
 None
 1.21A 1ea1A-3couA:
undetectable		 1ea1A-3couA:
19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A8T_A_ADNA252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3cou NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 16
(Homo
sapiens) 		5 / 9 HIS A  24
ARG A  50
GLY A  59
ILE A 164
GLN A 170
 None
 1.20A 2a8tA-3couA:
28.5		 2a8tA-3couA:
54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A8T_A_ADNA252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3cou NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 16
(Homo
sapiens) 		6 / 9 HIS A  24
ARG A  50
GLY A  60
PHE A  61
ILE A 164
GLN A 170
 None
 0.66A 2a8tA-3couA:
28.5		 2a8tA-3couA:
54.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3cou NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 16
(Homo
sapiens) 		5 / 8 HIS A  24
GLY A  56
PHE A  61
ILE A 164
GLN A 170
 None
 0.30A 2a8tB-3couA:
28.9		 2a8tB-3couA:
54.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3cou NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 16
(Homo
sapiens) 		4 / 6 LEU A 140
PRO A  58
LEU A  77
ALA A  85
 None
 0.96A 2vcvB-3couA:
undetectable		 2vcvB-3couA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3cou NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 16
(Homo
sapiens) 		5 / 9 LEU A  46
PRO A  58
LEU A  77
ALA A  85
PHE A  88
 None
 1.06A 2vcvD-3couA:
undetectable		 2vcvD-3couA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 3cou NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 16
(Homo
sapiens) 		3 / 3 GLU A  80
HIS A 133
VAL A 137
 None
 0.88A 5trqB-3couA:
undetectable		 5trqB-3couA:
20.86