SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		5 / 11 GLY A 166
GLY A 167
SER A 169
VAL A  12
HIS A  41
 FMT  A 219 (-3.5A)
FMT  A 219 (-3.6A)
FMT  A 219 (-2.6A)
None
FMT  A 219 (-3.9A)
 1.10A 1mx1A-3cp7A:
undetectable		 1mx1A-3cp7A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		5 / 12 GLY A 166
GLY A 167
SER A 169
VAL A  12
HIS A  41
 FMT  A 219 (-3.5A)
FMT  A 219 (-3.6A)
FMT  A 219 (-2.6A)
None
FMT  A 219 (-3.9A)
 1.00A 1mx1F-3cp7A:
undetectable		 1mx1F-3cp7A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		6 / 12 SER A 168
GLY A 170
GLY A 171
TRP A 173
ASP A  91
ASP A  87
 None
 1.14A 4b17A-3cp7A:
undetectable		 4b17A-3cp7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		5 / 12 VAL A  12
GLY A  40
SER A 169
SER A 168
GLY A 171
 None
None
FMT  A 219 (-2.6A)
None
None
 1.14A 4mmdB-3cp7A:
undetectable		 4mmdB-3cp7A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		4 / 7 THR A  35
ALA A  37
THR A  38
ALA A  39
 None
 1.01A 4qw0K-3cp7A:
undetectable		 4qw0K-3cp7A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		5 / 12 GLY A  64
GLY A 138
SER A 143
TYR A 128
PRO A   3
 None
 1.16A 4rtsA-3cp7A:
undetectable		 4rtsA-3cp7A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		4 / 6 GLY A  10
SER A  24
TYR A 130
GLY A 171
 None
 0.73A 5k4pA-3cp7A:
undetectable		 5k4pA-3cp7A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		5 / 12 HIS A  41
ASP A  91
GLY A 167
SER A 169
VAL A 197
 FMT  A 219 (-3.9A)
None
FMT  A 219 (-3.6A)
FMT  A 219 (-2.6A)
None
 1.05A 6c2mC-3cp7A:
6.1		 6c2mC-3cp7A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 3cp7 ALKALINE SERINE
PROTEASE AL20
(Nesterenkonia
aethiopica) 		4 / 6 TYR A 211
VAL A  77
VAL A  96
THR A  35
 None
 1.17A 6f32B-3cp7A:
undetectable		 6f32B-3cp7A:
18.88