SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cpg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 GLU A 251
ARG A  35
GLU A 211
ALA A 255
GLY A 257
 None
 1.28A 1cmaA-3cpgA:
undetectable
1cmaB-3cpgA:
undetectable		 1cmaA-3cpgA:
20.65
1cmaB-3cpgA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 ALA A 255
GLY A 257
GLU A 251
ARG A  35
GLU A 211
 None
 1.26A 1mj2A-3cpgA:
undetectable
1mj2B-3cpgA:
undetectable		 1mj2A-3cpgA:
20.65
1mj2B-3cpgA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 ALA A 255
GLY A 257
GLU A 251
ARG A  35
GLU A 211
 None
 1.29A 1mj2C-3cpgA:
undetectable
1mj2D-3cpgA:
undetectable		 1mj2C-3cpgA:
20.65
1mj2D-3cpgA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 ALA A 255
GLY A 257
GLU A 251
ARG A  35
GLU A 211
 None
 1.29A 1mjoC-3cpgA:
undetectable
1mjoD-3cpgA:
undetectable		 1mjoC-3cpgA:
20.65
1mjoD-3cpgA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 5 ILE A  36
LEU A  33
VAL A  29
ALA A  22
 None
 0.97A 1mz9C-3cpgA:
undetectable		 1mz9C-3cpgA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 LEU A  12
GLU A  82
PHE A 117
ILE A  75
GLU A  77
 None
 1.28A 1rnrA-3cpgA:
undetectable		 1rnrA-3cpgA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 LEU A  12
GLU A  82
PHE A 117
ILE A  75
GLU A  77
 None
 1.31A 1rnrB-3cpgA:
undetectable		 1rnrB-3cpgA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 9 PHE A 268
LEU A  52
VAL A  72
GLY A  71
ILE A  25
 None
 1.32A 2a1oB-3cpgA:
undetectable		 2a1oB-3cpgA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 11 ILE A 267
ALA A  55
MET A  74
SER A 258
THR A  56
 None
 0.89A 2blaA-3cpgA:
undetectable		 2blaA-3cpgA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 6 ILE A 150
ARG A 153
LEU A 132
LEU A 146
 None
 1.04A 2rlfA-3cpgA:
undetectable
2rlfD-3cpgA:
undetectable		 2rlfA-3cpgA:
8.87
2rlfD-3cpgA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_A_HNQA255_1
(CATHEPSIN B)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 7 GLN A 199
GLY A 162
HIS A 114
HIS A 118
 None
 0.96A 3ai8A-3cpgA:
undetectable		 3ai8A-3cpgA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 5 VAL A 134
VAL A 131
GLN A  81
ARG A  79
 None
 1.36A 3bjwH-3cpgA:
undetectable		 3bjwH-3cpgA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 5 VAL A 134
VAL A 131
GLN A  81
ARG A  79
 None
 1.39A 3bjwB-3cpgA:
undetectable		 3bjwB-3cpgA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		3 / 3 LEU A  52
LEU A  33
ARG A  31
 None
 0.70A 3hcnB-3cpgA:
3.0		 3hcnB-3cpgA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 ALA A  91
LEU A  90
ILE A 138
ILE A 120
PRO A  80
 None
 0.80A 3mb5A-3cpgA:
undetectable		 3mb5A-3cpgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 10 ILE A 267
ALA A  55
MET A  74
SER A 258
THR A  56
 None
 1.04A 3qg2A-3cpgA:
undetectable		 3qg2A-3cpgA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 8 ARG A 262
GLY A 200
GLY A 205
ASN A 168
 None
 0.98A 3v3nB-3cpgA:
undetectable		 3v3nB-3cpgA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 8 ARG A 262
GLY A 200
GLY A 205
ASN A 168
 None
 0.98A 3v3nC-3cpgA:
undetectable		 3v3nC-3cpgA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 ASP A 237
ALA A 187
GLY A 200
LEU A 201
GLY A 195
 None
 0.99A 5i73A-3cpgA:
undetectable		 5i73A-3cpgA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		5 / 12 ASP A 237
ALA A 187
GLY A 200
LEU A 201
GLY A 195
 None
 1.01A 5i75A-3cpgA:
undetectable		 5i75A-3cpgA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3cpg UNCHARACTERIZED
PROTEIN
(Bifidobacterium
adolescentis) 		4 / 5 ILE A 138
LEU A 101
GLY A 102
PHE A 117
 None
 0.93A 5kmdC-3cpgA:
undetectable
5kmdD-3cpgA:
undetectable		 5kmdC-3cpgA:
18.58
5kmdD-3cpgA:
18.58