SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cpq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A  51
VAL A  55
LYS A  56
ILE A  30
 None
 0.79A 2piwA-3cpqA:
undetectable		 2piwA-3cpqA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		5 / 10 THR A  29
VAL A  41
VAL A  66
ASP A  54
ILE A  30
 None
 1.47A 2qboA-3cpqA:
undetectable		 2qboA-3cpqA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		4 / 5 VAL A  42
TYR A  67
VAL A   9
SER A  97
 None
 1.11A 2x45A-3cpqA:
undetectable		 2x45A-3cpqA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1161_1
(ALLERGEN ARG R 1)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		4 / 4 VAL A  42
TYR A  67
VAL A   9
SER A  97
 None
 1.15A 2x45B-3cpqA:
undetectable		 2x45B-3cpqA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		4 / 5 VAL A  42
TYR A  67
VAL A   9
SER A  97
 None
 1.11A 2x45C-3cpqA:
undetectable		 2x45C-3cpqA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		5 / 12 VAL A   9
ILE A  99
ILE A  71
LEU A  89
ILE A  64
 None
 1.04A 4pd4C-3cpqA:
undetectable		 4pd4C-3cpqA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  25
ASP A  54
VAL A  55
ALA A  44
LEU A  43
 None
 1.02A 5kocA-3cpqA:
undetectable		 5kocA-3cpqA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  77
GLY A  25
ASP A  54
VAL A  55
ILE A  47
 None
 0.94A 5kqrA-3cpqA:
undetectable		 5kqrA-3cpqA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  77
GLY A  25
ASP A  54
VAL A  55
ILE A  47
 None
 0.92A 5m5bA-3cpqA:
undetectable		 5m5bA-3cpqA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3cpq 50S RIBOSOMAL
PROTEIN L30E
(Methanocaldococc
us
jannaschii) 		5 / 12 GLY A  77
GLY A  25
ASP A  54
VAL A  55
ILE A  47
 None
 0.91A 5njvD-3cpqA:
undetectable		 5njvD-3cpqA:
22.45