SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cq5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 110
HIS A 134
THR A 135
ILE A 164
 None
 0.70A 1c9sI-3cq5A:
undetectable
1c9sJ-3cq5A:
undetectable		 1c9sI-3cq5A:
13.50
1c9sJ-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 10 GLY A 110
HIS A 134
THR A 135
ILE A 164
GLY A 132
 None
 1.19A 1c9sN-3cq5A:
undetectable
1c9sO-3cq5A:
undetectable		 1c9sN-3cq5A:
13.50
1c9sO-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 110
HIS A 134
THR A 135
ILE A 164
 None
 0.63A 1c9sU-3cq5A:
undetectable
1c9sV-3cq5A:
undetectable		 1c9sU-3cq5A:
13.50
1c9sV-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 TYR A 239
LEU A 237
SER A 227
HIS A 126
LEU A 102
 None
None
PMP  A 401 (-2.6A)
None
None
 1.18A 1fmlA-3cq5A:
undetectable		 1fmlA-3cq5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 TYR A 239
LEU A 237
SER A 227
HIS A 126
LEU A 102
 None
None
PMP  A 401 (-2.6A)
None
None
 1.18A 1fmlB-3cq5A:
undetectable		 1fmlB-3cq5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 9 GLY A 132
GLY A 110
HIS A 134
THR A 135
ILE A 164
 None
 1.13A 1gtfD-3cq5A:
undetectable
1gtfE-3cq5A:
undetectable		 1gtfD-3cq5A:
13.50
1gtfE-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 9 GLY A 110
HIS A 134
THR A 135
ILE A 164
GLY A 132
 None
 1.19A 1gtfR-3cq5A:
undetectable
1gtfS-3cq5A:
undetectable		 1gtfR-3cq5A:
13.50
1gtfS-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 110
HIS A 134
THR A 135
ILE A 164
 None
 0.72A 1gtnA-3cq5A:
undetectable
1gtnB-3cq5A:
undetectable		 1gtnA-3cq5A:
13.50
1gtnB-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 10 GLY A  97
LEU A 129
GLN A 103
THR A 225
GLY A 238
 PMP  A 401 (-3.6A)
None
None
PMP  A 401 (-3.2A)
PMP  A 401 ( 4.5A)
 1.38A 1kvlA-3cq5A:
undetectable		 1kvlA-3cq5A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 PHE A 315
PHE A 325
LEU A 355
VAL A 291
ALA A 301
 None
 1.30A 1q23A-3cq5A:
undetectable
1q23B-3cq5A:
undetectable		 1q23A-3cq5A:
22.56
1q23B-3cq5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 110
HIS A 134
THR A 135
ILE A 164
 None
 0.69A 1utdB-3cq5A:
undetectable
1utdC-3cq5A:
undetectable		 1utdB-3cq5A:
13.50
1utdC-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 110
HIS A 134
THR A 135
ILE A 164
 None
 0.71A 1utdF-3cq5A:
undetectable
1utdG-3cq5A:
undetectable		 1utdF-3cq5A:
13.50
1utdG-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 110
HIS A 134
THR A 135
ILE A 164
 None
 0.68A 1utdI-3cq5A:
undetectable
1utdJ-3cq5A:
undetectable		 1utdI-3cq5A:
13.50
1utdJ-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 110
HIS A 134
THR A 135
ILE A 164
 None
 0.68A 1utdJ-3cq5A:
undetectable
1utdK-3cq5A:
undetectable		 1utdJ-3cq5A:
13.50
1utdK-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 10 GLY A 110
HIS A 134
THR A 135
ILE A 164
GLY A 132
 None
 1.17A 1utdU-3cq5A:
undetectable
1utdV-3cq5A:
undetectable		 1utdU-3cq5A:
13.50
1utdV-3cq5A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  75
LEU A 237
ALA A 265
ILE A 268
ALA A  68
 None
 0.95A 2bxcA-3cq5A:
undetectable		 2bxcA-3cq5A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 6 ALA A 249
PHE A 109
ILE A 193
VAL A 221
PHE A 240
 None
 1.40A 2cizA-3cq5A:
undetectable		 2cizA-3cq5A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 ASP A 276
LEU A  45
ALA A  44
ALA A 270
PHE A 232
 None
 1.23A 2ejtA-3cq5A:
3.8		 2ejtA-3cq5A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 10 ILE A 101
LEU A  92
ALA A  95
VAL A 250
ILE A 247
 None
 1.06A 2nnjA-3cq5A:
undetectable		 2nnjA-3cq5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 ALA A 153
ILE A 148
HIS A 126
THR A 178
 None
 0.81A 3dtuC-3cq5A:
undetectable
3dtuD-3cq5A:
undetectable		 3dtuC-3cq5A:
21.90
3dtuD-3cq5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 7 GLY A 329
VAL A  28
ILE A 332
GLN A 323
 None
 0.83A 3fi0E-3cq5A:
undetectable		 3fi0E-3cq5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 GLY A 329
VAL A  28
ILE A 332
GLN A 323
 None
 0.81A 3fi0I-3cq5A:
undetectable		 3fi0I-3cq5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 7 GLY A 329
VAL A  28
ILE A 332
GLN A 323
 None
 0.82A 3fi0P-3cq5A:
undetectable		 3fi0P-3cq5A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		3 / 3 ASP A 197
PHE A 166
SER A 124
 PMP  A 401 (-2.7A)
None
SO4  A 402 ( 3.7A)
 0.69A 3i5uB-3cq5A:
4.9		 3i5uB-3cq5A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 7 LEU A 298
VAL A 335
ILE A 332
ARG A 142
 None
 1.30A 3ik3B-3cq5A:
undetectable		 3ik3B-3cq5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		3 / 3 PRO A 170
SER A 305
ASN A 172
 None
None
SO4  A 402 ( 3.4A)
 0.83A 3lslG-3cq5A:
undetectable		 3lslG-3cq5A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 THR A 343
ARG A 342
GLY A 313
PHE A 312
 None
SO4  A 402 (-3.0A)
None
None
 1.04A 3tzfB-3cq5A:
undetectable		 3tzfB-3cq5A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 7 LEU A 271
ARG A 224
PRO A  41
SER A  42
 None
 1.23A 4klrA-3cq5A:
2.4		 4klrA-3cq5A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 PHE A 309
TYR A 200
THR A 174
VAL A 335
 None
PMP  A 401 (-4.3A)
None
None
 1.10A 4l4dA-3cq5A:
undetectable		 4l4dA-3cq5A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 PHE A 309
TYR A 200
THR A 174
VAL A 335
 None
PMP  A 401 (-4.3A)
None
None
 1.12A 4l4eA-3cq5A:
undetectable		 4l4eA-3cq5A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 PHE A 309
TYR A 200
THR A 174
VAL A 335
 None
PMP  A 401 (-4.3A)
None
None
 1.12A 4l4fA-3cq5A:
undetectable		 4l4fA-3cq5A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  32
VAL A 291
GLY A 299
PHE A 312
THR A 343
 None
 1.31A 4mubA-3cq5A:
undetectable		 4mubA-3cq5A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 5 LEU A 259
ASP A  67
ARG A  72
ILE A 247
 None
 1.21A 4mwrA-3cq5A:
undetectable		 4mwrA-3cq5A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 11 ILE A 268
LEU A 237
LEU A 259
ALA A  94
LEU A  75
 None
 0.94A 4p65E-3cq5A:
undetectable
4p65F-3cq5A:
undetectable
4p65J-3cq5A:
undetectable
4p65L-3cq5A:
undetectable		 4p65E-3cq5A:
5.69
4p65F-3cq5A:
9.39
4p65J-3cq5A:
9.39
4p65L-3cq5A:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  75
ILE A 268
LEU A 237
LEU A 259
ALA A  94
 None
 0.99A 4p65B-3cq5A:
undetectable
4p65D-3cq5A:
undetectable
4p65I-3cq5A:
undetectable
4p65J-3cq5A:
undetectable		 4p65B-3cq5A:
9.39
4p65D-3cq5A:
9.39
4p65I-3cq5A:
5.69
4p65J-3cq5A:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 LEU A  75
ILE A 268
LEU A 237
LEU A 259
ALA A  94
 None
 1.05A 4p65F-3cq5A:
undetectable
4p65H-3cq5A:
undetectable
4p65K-3cq5A:
undetectable
4p65L-3cq5A:
undetectable		 4p65F-3cq5A:
9.39
4p65H-3cq5A:
9.39
4p65K-3cq5A:
5.69
4p65L-3cq5A:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		3 / 3 MET A 150
ASP A 176
PHE A 146
 None
 0.92A 4xeyA-3cq5A:
undetectable		 4xeyA-3cq5A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		3 / 3 MET A 150
ASP A 176
PHE A 146
 None
 0.96A 4xeyB-3cq5A:
undetectable		 4xeyB-3cq5A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 7 ILE A 362
GLY A 299
PHE A 311
ASP A 314
 None
 1.01A 5hieA-3cq5A:
undetectable		 5hieA-3cq5A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		5 / 12 ILE A 247
THR A 210
PHE A 109
ALA A 108
SER A  98
 None
None
None
None
PMP  A 401 (-3.3A)
 1.31A 5iwuA-3cq5A:
undetectable		 5iwuA-3cq5A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 6 ASN A  33
LEU A 331
ARG A 328
GLY A 329
 None
 1.09A 5o4yA-3cq5A:
undetectable		 5o4yA-3cq5A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 8 SER A 122
THR A 168
PHE A 137
ILE A 164
 None
PMP  A 401 (-3.9A)
None
None
 1.12A 5vkqB-3cq5A:
3.3
5vkqC-3cq5A:
3.3		 5vkqB-3cq5A:
12.49
5vkqC-3cq5A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 6 GLY A 175
ASN A 171
ASP A 176
ARG A 142
 None
 1.21A 6dwdA-3cq5A:
undetectable
6dwdC-3cq5A:
undetectable		 6dwdA-3cq5A:
20.32
6dwdC-3cq5A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE
(Corynebacterium
glutamicum) 		4 / 5 GLY A 175
ASN A 171
ASP A 176
ARG A 142
 None
 1.20A 6dwdB-3cq5A:
undetectable
6dwdD-3cq5A:
undetectable		 6dwdB-3cq5A:
20.32
6dwdD-3cq5A:
20.32