SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 12 ASP A  95
ILE A 129
HIS A  98
ILE A   4
PHE A  89
 None
 1.15A 1fkbA-3cq9A:
undetectable		 1fkbA-3cq9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 11 ASP A  95
ILE A 129
HIS A  98
ILE A   4
PHE A  89
 None
 1.17A 2dg4A-3cq9A:
undetectable		 2dg4A-3cq9A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 11 ASP A  95
ILE A 129
HIS A  98
ILE A   4
PHE A  89
 None
 1.17A 2dg9A-3cq9A:
undetectable		 2dg9A-3cq9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 12 ILE A 129
LEU A 131
ASN A 136
VAL A  97
ILE A 209
 None
 1.21A 2vn0A-3cq9A:
undetectable		 2vn0A-3cq9A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		3 / 3 LEU A  20
ARG A  36
ILE A  42
 None
 0.60A 2xn5B-3cq9A:
undetectable		 2xn5B-3cq9A:
12.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 7 TYR A 174
LEU A 169
SER A 189
ASN A 190
 None
 1.03A 3lm8A-3cq9A:
23.8
3lm8C-3cq9A:
23.3		 3lm8A-3cq9A:
41.35
3lm8C-3cq9A:
41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 7 TYR A 174
LEU A 176
SER A 189
ASN A 190
 None
 0.40A 3lm8A-3cq9A:
23.8
3lm8C-3cq9A:
23.3		 3lm8A-3cq9A:
41.35
3lm8C-3cq9A:
41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 7 TYR A 174
LEU A 169
SER A 189
ASN A 190
 None
 1.02A 3lm8B-3cq9A:
23.9
3lm8D-3cq9A:
22.3		 3lm8B-3cq9A:
41.35
3lm8D-3cq9A:
41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 7 TYR A 174
LEU A 176
SER A 189
ASN A 190
 None
 0.38A 3lm8B-3cq9A:
23.9
3lm8D-3cq9A:
22.3		 3lm8B-3cq9A:
41.35
3lm8D-3cq9A:
41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 8 TYR A 174
LEU A 169
SER A 189
ASN A 190
 None
 0.99A 3lm8A-3cq9A:
23.8
3lm8C-3cq9A:
23.3		 3lm8A-3cq9A:
41.35
3lm8C-3cq9A:
41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 8 TYR A 174
LEU A 176
SER A 189
ASN A 190
 None
 0.58A 3lm8A-3cq9A:
23.8
3lm8C-3cq9A:
23.3		 3lm8A-3cq9A:
41.35
3lm8C-3cq9A:
41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 8 TYR A 174
LEU A 169
SER A 189
ASN A 190
 None
 0.95A 3lm8B-3cq9A:
23.9
3lm8D-3cq9A:
22.3		 3lm8B-3cq9A:
41.35
3lm8D-3cq9A:
41.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 8 TYR A 174
LEU A 176
SER A 189
ASN A 190
 None
 0.41A 3lm8B-3cq9A:
23.9
3lm8D-3cq9A:
22.3		 3lm8B-3cq9A:
41.35
3lm8D-3cq9A:
41.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 7 LEU A  66
VAL A  47
LEU A  83
ASP A  50
 None
 0.93A 3rgfA-3cq9A:
undetectable		 3rgfA-3cq9A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 12 VAL A  28
GLY A  29
VAL A  48
PRO A  94
TRP A 125
 None
 1.49A 4bvaA-3cq9A:
2.7		 4bvaA-3cq9A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 12 ILE A  70
VAL A  72
ALA A  84
SER A  87
LEU A  92
 None
 0.88A 4o1zA-3cq9A:
undetectable		 4o1zA-3cq9A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		4 / 5 TYR A  16
TYR A 100
GLY A 101
GLY A  11
 None
 1.14A 5x7pA-3cq9A:
4.2		 5x7pA-3cq9A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 12 GLU A 151
LEU A 167
LEU A 176
SER A 137
LEU A 206
 None
 1.12A 6ew0B-3cq9A:
undetectable		 6ew0B-3cq9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 12 GLU A 151
LEU A 167
LEU A 176
SER A 137
LEU A 206
 None
 1.12A 6ew0D-3cq9A:
undetectable		 6ew0D-3cq9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 12 GLU A 151
LEU A 167
LEU A 176
SER A 137
LEU A 206
 None
 1.12A 6ew0H-3cq9A:
undetectable		 6ew0H-3cq9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 3cq9 UNCHARACTERIZED
PROTEIN LP_1622
(Lactobacillus
plantarum) 		5 / 12 GLU A 151
LEU A 167
LEU A 176
SER A 137
LEU A 206
 None
 1.12A 6ew0I-3cq9A:
undetectable		 6ew0I-3cq9A:
16.84