SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BZF_A_TMQA170_1 (DIHYDROFOLATE REDUCTASE)	3cqb	PROBABLE PROTEASE HTPX HOMOLOG (Vibrio parahaemolyticus)	5 / 12	LEU A 84 LEU A 71 PHE A 54 ALA A 44 THR A 21	None None None None CL A 105 ( 4.1A)	1.06A	1bzfA-3cqbA: undetectable	1bzfA-3cqbA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V5W_A_8PRA701_2 (G-PROTEIN COUPLED RECEPTOR KINASE 2)	3cqb	PROBABLE PROTEASE HTPX HOMOLOG (Vibrio parahaemolyticus)	3 / 3	LEU A 72 MET A 75 ASP A 78	CL A 105 ( 4.3A) None None	0.89A	3v5wA-3cqbA: undetectable	3v5wA-3cqbA: 9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1478_0 (MJ0495-LIKE PROTEIN)	3cqb	PROBABLE PROTEASE HTPX HOMOLOG (Vibrio parahaemolyticus)	4 / 7	GLY A 70 THR A 69 THR A 98 PHE A 54	None	1.03A	4ac9C-3cqbA: undetectable	4ac9C-3cqbA: 11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OQR_A_2UOA502_1 (CYP105AS1)	3cqb	PROBABLE PROTEASE HTPX HOMOLOG (Vibrio parahaemolyticus)	5 / 9	VAL A 83 ILE A 14 VAL A 43 ALA A 44 ALA A 53	None	1.15A	4oqrA-3cqbA: undetectable	4oqrA-3cqbA: 12.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BZF_A_TMQA170_1","DIHYDROFOLATE REDUCTASE","3cqb","PROBABLE PROTEASE HTPX HOMOLOG","Vibrio parahaemolyticus",5,"LEU A  84;LEU A  71;PHE A  54;ALA A  44;THR A  21","None;None;None;None; CL A 105 ( 4.1A)","1.06A","1bzfA-3cqbA:undetectable","1bzfA-3cqbA:23.12"],["3V5W_A_8PRA701_2","G-PROTEIN COUPLED RECEPTOR KINASE 2","3cqb","PROBABLE PROTEASE HTPX HOMOLOG","Vibrio parahaemolyticus",3,"LEU A  72;MET A  75;ASP A  78"," CL A 105 ( 4.3A);None;None","0.89A","3v5wA-3cqbA:undetectable","3v5wA-3cqbA:9.66"],["4AC9_C_DXCC1478_0","MJ0495-LIKE PROTEIN","3cqb","PROBABLE PROTEASE HTPX HOMOLOG","Vibrio parahaemolyticus",4,"GLY A  70;THR A  69;THR A  98;PHE A  54","None","1.03A","4ac9C-3cqbA:undetectable","4ac9C-3cqbA:11.79"],["4OQR_A_2UOA502_1","CYP105AS1","3cqb","PROBABLE PROTEASE HTPX HOMOLOG","Vibrio parahaemolyticus",5,"VAL A  83;ILE A  14;VAL A  43;ALA A  44;ALA A  53","None","1.15A","4oqrA-3cqbA:undetectable","4oqrA-3cqbA:12.83"]]