SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cqg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107
(Homo
sapiens) 		4 / 6 LEU A 875
LEU A 865
LEU A 821
LEU A 822
 None
 0.83A 1errA-3cqgA:
undetectable		 1errA-3cqgA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107
(Homo
sapiens) 		4 / 4 ALA A 707
VAL A 711
ALA A 708
HIS A 705
 None
 1.02A 1q23A-3cqgA:
undetectable		 1q23A-3cqgA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107
(Homo
sapiens) 		4 / 4 ALA A 707
VAL A 711
ALA A 708
HIS A 705
 None
 1.01A 1q23K-3cqgA:
undetectable		 1q23K-3cqgA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107
(Homo
sapiens) 		5 / 9 LEU A 736
LEU A 689
ILE A 720
ALA A 721
ALA A 686
 None
 1.12A 3mdvA-3cqgA:
undetectable		 3mdvA-3cqgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107
(Homo
sapiens) 		4 / 7 HIS A 747
ILE A 723
ILE A 744
ALA A 743
 None
 0.87A 4lv9A-3cqgA:
undetectable		 4lv9A-3cqgA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107
(Homo
sapiens) 		4 / 5 TYR A 818
GLU A 873
LEU A 861
GLN A 870
 None
 1.02A 4qztB-3cqgA:
undetectable		 4qztB-3cqgA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107
(Homo
sapiens) 		5 / 12 LEU A 754
ARG A 751
PHE A 699
GLU A 710
LEU A 700
 None
 1.32A 5czyA-3cqgA:
undetectable		 5czyA-3cqgA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 3cqg NUCLEAR PORE COMPLEX
PROTEIN NUP107
(Homo
sapiens) 		4 / 6 ILE A 744
TYR A 724
LEU A 736
ARG A 833
 None
 1.24A 6f6jA-3cqgA:
undetectable		 6f6jA-3cqgA:
undetectable