SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cqh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		3 / 3 PHE A 232
VAL A 271
TRP A 270
 SO4  A 405 (-4.4A)
None
None
 0.75A 2cc8A-3cqhA:
undetectable		 2cc8A-3cqhA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		3 / 3 PHE A 232
VAL A 271
TRP A 270
 SO4  A 405 (-4.4A)
None
None
 0.75A 2ccbA-3cqhA:
undetectable		 2ccbA-3cqhA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEO_A_LNRA200_1
(D7R4 PROTEIN)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		5 / 12 GLU A  12
ARG A  46
ILE A  10
GLU A 255
ASP A  41
 None
 1.49A 2qeoA-3cqhA:
undetectable		 2qeoA-3cqhA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		3 / 3 PHE A 232
VAL A 271
TRP A 270
 SO4  A 405 (-4.4A)
None
None
 0.74A 2vx9A-3cqhA:
undetectable		 2vx9A-3cqhA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		4 / 7 LEU A 189
GLU A 155
ASP A 120
THR A 215
 None
 1.18A 3dzgB-3cqhA:
2.2		 3dzgB-3cqhA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		4 / 4 LEU A  15
PRO A  16
LEU A  27
ARG A 268
 None
 1.48A 3hcoA-3cqhA:
undetectable		 3hcoA-3cqhA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		4 / 4 LEU A  15
PRO A  16
LEU A  27
ARG A 268
 None
 1.21A 3hcoB-3cqhA:
undetectable		 3hcoB-3cqhA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		5 / 12 GLU A 251
TYR A  11
TYR A 183
HIS A 211
GLY A 187
 None
SO4  A 402 (-4.4A)
None
None
None
 1.41A 3rlbB-3cqhA:
undetectable		 3rlbB-3cqhA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		5 / 10 PHE A 232
ILE A 186
GLY A 187
THR A 215
PHE A 225
 SO4  A 405 (-4.4A)
None
None
None
None
 1.29A 3t3rD-3cqhA:
undetectable		 3t3rD-3cqhA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		4 / 5 LEU A  15
ILE A 250
MET A 252
PHE A  33
 None
 0.97A 4dc3B-3cqhA:
undetectable		 4dc3B-3cqhA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		4 / 7 GLU A  42
GLY A 118
TYR A 119
TYR A 122
 None
 0.72A 5uxdA-3cqhA:
undetectable		 5uxdA-3cqhA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		4 / 5 LEU A 175
PHE A 180
LEU A 138
PHE A 134
 None
 1.00A 5x19C-3cqhA:
undetectable
5x19J-3cqhA:
undetectable		 5x19C-3cqhA:
21.36
5x19J-3cqhA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE
(Escherichia
coli) 		4 / 4 ARG A  24
GLU A  12
GLU A  19
ARG A  49
 None
 0.94A 6fk2A-3cqhA:
undetectable		 6fk2A-3cqhA:
17.92