SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3cql ENDOCHITINASE
(Carica
papaya) 		4 / 7 SER A 120
TYR A 123
ASN A 122
TYR A 125
 NAG  A 245 (-3.7A)
None
None
None
 1.04A 1dssG-3cqlA:
undetectable		 1dssG-3cqlA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3cql ENDOCHITINASE
(Carica
papaya) 		5 / 11 PHE A  34
ILE A 117
ALA A 154
LEU A 155
ALA A  37
 None
NAG  A 245 (-4.3A)
None
None
None
 1.10A 1jb0B-3cqlA:
undetectable		 1jb0B-3cqlA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3cql ENDOCHITINASE
(Carica
papaya) 		3 / 3 ALA A 154
THR A  64
PHE A  41
 None
 0.58A 2c6nB-3cqlA:
undetectable		 2c6nB-3cqlA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3cql ENDOCHITINASE
(Carica
papaya) 		4 / 6 PHE A 218
ARG A 215
GLY A  83
THR A  69
 None
NDG  A 244 (-4.4A)
None
None
 1.15A 2f7fA-3cqlA:
undetectable		 2f7fA-3cqlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3cql ENDOCHITINASE
(Carica
papaya) 		5 / 11 GLY A  45
GLU A  56
PHE A  60
ALA A  38
ILE A   2
 None
 1.26A 3id5B-3cqlA:
undetectable		 3id5B-3cqlA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3cql ENDOCHITINASE
(Carica
papaya) 		5 / 11 GLY A  45
GLU A  56
PHE A  60
ALA A  38
ILE A   2
 None
 1.26A 3id5F-3cqlA:
undetectable		 3id5F-3cqlA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3cql ENDOCHITINASE
(Carica
papaya) 		5 / 11 PHE A  34
ILE A 117
ALA A 154
LEU A 155
ALA A  37
 None
NAG  A 245 (-4.3A)
None
None
None
 1.10A 3pcqB-3cqlA:
undetectable		 3pcqB-3cqlA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3cql ENDOCHITINASE
(Carica
papaya) 		4 / 7 TYR A  96
GLU A 203
GLN A 118
PRO A 241
 None
NDG  A 244 (-3.3A)
NDG  A 244 (-3.9A)
None
 1.14A 3ugrA-3cqlA:
undetectable		 3ugrA-3cqlA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 3cql ENDOCHITINASE
(Carica
papaya) 		5 / 12 GLY A  45
ILE A   2
ILE A 172
LEU A 155
LEU A  61
 None
 1.00A 4pd4C-3cqlA:
undetectable		 4pd4C-3cqlA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 3cql ENDOCHITINASE
(Carica
papaya) 		3 / 3 GLN A 211
HIS A  66
ARG A 215
 None
NDG  A 244 (-3.9A)
NDG  A 244 (-4.4A)
 1.31A 4qyqA-3cqlA:
undetectable		 4qyqA-3cqlA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 3cql ENDOCHITINASE
(Carica
papaya) 		3 / 3 GLN A 211
HIS A  66
ARG A 215
 None
NDG  A 244 (-3.9A)
NDG  A 244 (-4.4A)
 1.26A 4qyqB-3cqlA:
undetectable		 4qyqB-3cqlA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3cql ENDOCHITINASE
(Carica
papaya) 		4 / 5 ILE A   6
PHE A  28
SER A   9
ASP A  32
 None
None
None
GOL  A 248 (-3.4A)
 1.42A 4rzvB-3cqlA:
undetectable		 4rzvB-3cqlA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3cql ENDOCHITINASE
(Carica
papaya) 		5 / 12 PHE A  34
ILE A 117
ALA A 154
LEU A 155
ALA A  37
 None
NAG  A 245 (-4.3A)
None
None
None
 1.01A 5oy02-3cqlA:
undetectable		 5oy02-3cqlA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3cql ENDOCHITINASE
(Carica
papaya) 		5 / 10 PHE A  34
ILE A 117
ALA A 154
LEU A 155
ALA A  37
 None
NAG  A 245 (-4.3A)
None
None
None
 1.06A 5oy0b-3cqlA:
undetectable		 5oy0b-3cqlA:
13.72