SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cqo FBP32
(Morone
saxatilis) 		5 / 11 THR A  64
SER A  65
LEU A  57
VAL A  55
VAL A   6
 None
 1.43A 1q23J-3cqoA:
undetectable		 1q23J-3cqoA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3cqo FBP32
(Morone
saxatilis) 		5 / 10 THR A  64
SER A  65
LEU A  57
VAL A  55
VAL A   6
 None
 1.46A 1q23K-3cqoA:
undetectable		 1q23K-3cqoA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3cqo FBP32
(Morone
saxatilis) 		5 / 8 ILE A 114
ARG A  54
ILE A 103
VAL A 125
ALA A   7
 None
 1.16A 2nniA-3cqoA:
undetectable		 2nniA-3cqoA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 3cqo FBP32
(Morone
saxatilis) 		3 / 3 LEU A 235
TYR A 268
GLY A 266
 None
 0.61A 2ocuA-3cqoA:
undetectable		 2ocuA-3cqoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3cqo FBP32
(Morone
saxatilis) 		4 / 6 VAL A 127
PRO A  51
THR A  45
TRP A  53
 None
 1.47A 2q6oB-3cqoA:
undetectable		 2q6oB-3cqoA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3cqo FBP32
(Morone
saxatilis) 		5 / 10 VAL A 125
LEU A  57
GLY A  87
VAL A 120
GLY A 122
 None
 1.30A 3ls4H-3cqoA:
2.2		 3ls4H-3cqoA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)		 3cqo FBP32
(Morone
saxatilis) 		4 / 5 SER A 290
TYR A 146
VAL A   6
ASP A 293
 None
 1.49A 4eohB-3cqoA:
undetectable		 4eohB-3cqoA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3cqo FBP32
(Morone
saxatilis) 		6 / 12 GLY A  94
VAL A 141
ILE A  66
PHE A 116
GLY A 122
GLY A  87
 None
 1.39A 5koxA-3cqoA:
undetectable		 5koxA-3cqoA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 3cqo FBP32
(Morone
saxatilis) 		5 / 9 ALA A  28
VAL A 143
ALA A   7
VAL A 125
GLY A  10
 None
 1.28A 6bklA-3cqoA:
undetectable
6bklB-3cqoA:
undetectable
6bklC-3cqoA:
undetectable
6bklD-3cqoA:
undetectable		 6bklA-3cqoA:
6.14
6bklB-3cqoA:
6.14
6bklC-3cqoA:
6.14
6bklD-3cqoA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 3cqo FBP32
(Morone
saxatilis) 		3 / 3 ARG A 147
LYS A   4
TYR A   1
 None
 1.25A 6gnaA-3cqoA:
undetectable		 6gnaA-3cqoA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 3cqo FBP32
(Morone
saxatilis) 		3 / 3 ARG A 147
LYS A   4
TYR A   1
 None
 1.25A 6gnbA-3cqoA:
undetectable		 6gnbA-3cqoA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3cqo FBP32
(Morone
saxatilis) 		4 / 6 ASP A 293
TYR A  61
GLU A  59
GLU A 152
 None
 0.98A 6mn5A-3cqoA:
undetectable		 6mn5A-3cqoA:
15.70