SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cr3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 7 PHE C  88
VAL C  90
ILE C   7
GLY C  95
 None
 0.92A 11gsA-3cr3C:
undetectable		 11gsA-3cr3C:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 8 PHE C  88
VAL C  90
ILE C   7
GLY C  95
 None
 0.92A 2gssA-3cr3C:
undetectable		 2gssA-3cr3C:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 8 PHE C  88
VAL C  90
ILE C   7
GLY C  95
 None
 0.92A 2gssB-3cr3C:
undetectable		 2gssB-3cr3C:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A933_1
(ANDROGEN RECEPTOR)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		5 / 10 ILE C  34
GLY A  76
GLU C  41
ASN C  39
GLU C  38
 None
 1.39A 2piwA-3cr3C:
undetectable		 2piwA-3cr3C:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		5 / 12 ILE C 112
ILE C  53
ILE C  87
THR C  86
VAL C   8
 None
 1.14A 2qo5A-3cr3C:
undetectable		 2qo5A-3cr3C:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 5 SER C  45
ARG C  48
PRO C  12
GLY C  35
 None
 1.10A 2y7kB-3cr3C:
undetectable		 2y7kB-3cr3C:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 6 SER C  45
ARG C  48
PRO C  12
GLY C  35
 None
 1.34A 2y7pA-3cr3C:
undetectable		 2y7pA-3cr3C:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		4 / 7 TRP A  10
VAL A 191
THR A 100
LEU A 103
 None
 1.07A 3arrA-3cr3A:
undetectable		 3arrA-3cr3A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		4 / 7 TRP A  10
VAL A 191
THR A 100
TRP A 128
 None
 0.98A 3arrA-3cr3A:
undetectable		 3arrA-3cr3A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		5 / 12 GLN A 178
ASP A 126
GLY A 120
SER A 169
ALA A 157
 None
 1.09A 3d91A-3cr3A:
undetectable		 3d91A-3cr3A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		5 / 9 LEU A 187
VAL A 191
ILE A 104
LEU A 135
THR A   6
 None
 1.35A 3fl9H-3cr3A:
undetectable		 3fl9H-3cr3A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 8 PHE C  88
VAL C  90
ILE C   7
GLY C  95
 None
 0.95A 3hjoA-3cr3C:
undetectable		 3hjoA-3cr3C:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis;
Lactococcus
lactis) 		5 / 12 ASP A  34
GLY C  43
SER C   9
PHE C  65
ILE C  42
 MG  A1213 (-2.7A)
None
None
None
None
 1.04A 3k13C-3cr3A:
undetectable		 3k13C-3cr3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 7 GLU C  54
VAL C  77
VAL C   6
ALA C  52
 None
 1.06A 3kp6B-3cr3C:
undetectable		 3kp6B-3cr3C:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis;
Lactococcus
lactis) 		5 / 12 HIS C  10
ASP A  36
HIS A  37
GLY A  33
LEU A  28
 None
MG  A1212 (-2.5A)
ADP  A1211 (-4.0A)
None
None
 0.97A 4blvB-3cr3C:
undetectable		 4blvB-3cr3C:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		5 / 11 SER A  79
MET A  90
PHE A  64
THR A  48
ALA A  51
 ADP  A1211 (-2.8A)
None
None
None
None
 1.37A 4dx7A-3cr3A:
1.5		 4dx7A-3cr3A:
12.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 7 LEU C  67
ILE C  42
THR C  44
GLY A  77
 None
None
None
ADP  A1211 (-3.3A)
 0.92A 4eqlB-3cr3C:
undetectable		 4eqlB-3cr3C:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 6 LEU C  67
ILE C  42
THR C  44
GLY A  77
 None
None
None
ADP  A1211 (-3.3A)
 0.86A 4l39A-3cr3C:
undetectable		 4l39A-3cr3C:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		4 / 7 LEU C  67
ILE C  42
THR C  44
GLY A  77
 None
None
None
ADP  A1211 (-3.3A)
 0.88A 4l39B-3cr3C:
undetectable		 4l39B-3cr3C:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		4 / 6 ASP A  36
ASP A  34
TYR A 164
ASP A  29
 MG  A1212 (-2.5A)
MG  A1213 (-2.7A)
None
MG  A1212 ( 2.6A)
 1.13A 4mdaA-3cr3A:
undetectable		 4mdaA-3cr3A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		4 / 6 ASP A  36
ASP A  34
TYR A 164
ASP A  29
 MG  A1212 (-2.5A)
MG  A1213 (-2.7A)
None
MG  A1212 ( 2.6A)
 1.06A 4mdbA-3cr3A:
undetectable		 4mdbA-3cr3A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		3 / 3 ALA A 140
ASN A 144
LEU A 145
 None
 0.44A 5i1nC-3cr3A:
undetectable		 5i1nC-3cr3A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		3 / 3 ALA C  70
ASN C  73
LEU C  74
 None
 0.41A 5i1nC-3cr3C:
undetectable		 5i1nC-3cr3C:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		3 / 3 ALA C  70
ASN C  73
LEU C  74
 None
 0.38A 5i1oC-3cr3C:
undetectable		 5i1oC-3cr3C:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		3 / 3 ALA C  70
ASN C  73
LEU C  74
 None
 0.39A 5i1pA-3cr3C:
undetectable		 5i1pA-3cr3C:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		3 / 3 ALA A 140
ASN A 144
LEU A 145
 None
 0.44A 5i1pD-3cr3A:
undetectable		 5i1pD-3cr3A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM
(Lactococcus
lactis) 		3 / 3 ALA C  70
ASN C  73
LEU C  74
 None
 0.46A 5i1pD-3cr3C:
undetectable		 5i1pD-3cr3C:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		4 / 8 LEU A  71
MET A  45
LEU A  52
ILE A  63
 None
 0.93A 5mzjA-3cr3A:
2.7		 5mzjA-3cr3A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE, ADP-BINDING
SUBUNIT DHAL
(Lactococcus
lactis) 		4 / 7 GLN A 118
GLY A 120
TYR A  83
ASP A 174
 None
None
None
ADP  A1211 (-2.7A)
 0.90A 5vlmE-3cr3A:
undetectable		 5vlmE-3cr3A:
21.96