SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3cs1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		5 / 11 PHE A 186
ARG A  93
ALA A 190
LEU A 176
VAL A 184
 None
 1.08A 2bxeB-3cs1A:
undetectable		 2bxeB-3cs1A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		3 / 3 LEU A 101
TRP A 192
TYR A 125
 None
 1.01A 3aicA-3cs1A:
undetectable		 3aicA-3cs1A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		3 / 3 LEU A 101
TRP A 192
TYR A 125
 None
 0.99A 3aicB-3cs1A:
undetectable		 3aicB-3cs1A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		3 / 3 LEU A 101
TRP A 192
TYR A 125
 None
 0.99A 3aicE-3cs1A:
undetectable		 3aicE-3cs1A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		3 / 3 LEU A 101
TRP A 192
TYR A 125
 None
 0.97A 3aicF-3cs1A:
undetectable		 3aicF-3cs1A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		3 / 3 LEU A 101
TRP A 192
TYR A 125
 None
 0.99A 3aicH-3cs1A:
undetectable		 3aicH-3cs1A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		4 / 8 ILE A  38
TRP A  31
PHE A 130
ARG A  33
 None
 1.24A 3ccfB-3cs1A:
undetectable		 3ccfB-3cs1A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		3 / 3 LYS A  59
LYS A  67
SER A  72
 None
CSX  A  66 ( 2.8A)
None
 1.08A 5odiA-3cs1A:
undetectable		 5odiA-3cs1A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 3cs1 FLAGELLAR
CALCIUM-BINDING
PROTEIN
(Trypanosoma
cruzi) 		3 / 3 ARG A 120
PHE A 130
LEU A 198
 None
 0.86A 5veuA-3cs1A:
undetectable		 5veuA-3cs1A:
19.14