SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3csg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 6 VAL A   8
VAL A  50
ILE A  60
ASN A 267
 None
 0.95A 1e06A-3csgA:
undetectable		 1e06A-3csgA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 6 TRP A 392
ILE A 104
TYR A  99
GLY A 101
 None
 1.03A 1maaB-3csgA:
undetectable
1maaD-3csgA:
undetectable		 1maaB-3csgA:
20.52
1maaD-3csgA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 10 LEU A 192
LEU A 195
ILE A 161
GLU A 153
LEU A 151
 None
 1.12A 1wopA-3csgA:
undetectable		 1wopA-3csgA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 11 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.10A 2f16H-3csgA:
undetectable
2f16I-3csgA:
undetectable		 2f16H-3csgA:
18.61
2f16I-3csgA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 11 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.11A 2f16V-3csgA:
undetectable
2f16W-3csgA:
undetectable		 2f16V-3csgA:
18.61
2f16W-3csgA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 11 ALA A 303
ILE A 108
VAL A  97
LEU A  76
ILE A  79
 None
 1.25A 2h42A-3csgA:
undetectable		 2h42A-3csgA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 12 ALA A 264
LEU A 280
PHE A 279
VAL A 293
GLY A  16
 None
 1.04A 2ve3A-3csgA:
undetectable		 2ve3A-3csgA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 12 PRO A 133
MET A 204
ILE A 199
LEU A 160
LEU A 192
 None
 1.26A 3a50E-3csgA:
undetectable		 3a50E-3csgA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 12 ILE A 108
LEU A 262
ILE A  59
VAL A  23
LEU A  20
 None
 1.00A 3a51C-3csgA:
undetectable		 3a51C-3csgA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 11 VAL A 421
PRO A 422
ILE A 441
ILE A 457
PRO A 456
 None
 1.46A 3ganA-3csgA:
undetectable		 3ganA-3csgA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 6 PRO A 126
LEU A 147
ALA A 223
PRO A 125
 None
 1.29A 3gv1A-3csgA:
undetectable
3gv1C-3csgA:
undetectable		 3gv1A-3csgA:
13.67
3gv1C-3csgA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 6 LEU A 147
ALA A 223
PRO A 125
PRO A 126
 None
 1.27A 3gv1A-3csgA:
undetectable
3gv1B-3csgA:
undetectable		 3gv1A-3csgA:
13.67
3gv1B-3csgA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 12 VAL A 343
GLY A 187
ALA A 188
LEU A 192
LEU A 160
 None
 1.01A 3hs6A-3csgA:
undetectable		 3hs6A-3csgA:
21.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 7 GLU A 153
TYR A 155
MET A 330
TRP A 340
 None
 0.81A 3jyrA-3csgA:
36.7		 3jyrA-3csgA:
88.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 11 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.12A 3mg0H-3csgA:
undetectable
3mg0I-3csgA:
undetectable		 3mg0H-3csgA:
18.61
3mg0I-3csgA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 12 VAL A 196
LEU A 160
GLY A 187
ALA A 188
LEU A 361
 None
 1.00A 3n8yB-3csgA:
undetectable		 3n8yB-3csgA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		6 / 11 GLY A 300
ALA A 301
VAL A 259
GLY A 260
THR A  93
PRO A 107
 None
 1.30A 3ufnA-3csgA:
undetectable		 3ufnA-3csgA:
14.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VFJ_A_ACTA410_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN,
C-TERMINAL FUSED BY
CYS-LYS-D-ALA-D-ALA)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 4 LYS A  15
ALA A  63
GLU A 111
LEU A 262
 None
 0.66A 3vfjA-3csgA:
54.5		 3vfjA-3csgA:
82.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 5 ASN A 267
ALA A  51
GLY A  56
ASP A  14
 None
 0.95A 4n48A-3csgA:
undetectable		 4n48A-3csgA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 7 LEU A  76
GLY A 265
ALA A 264
SER A 263
 None
 0.91A 5f1aB-3csgA:
undetectable		 5f1aB-3csgA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 12 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.15A 5l66H-3csgA:
undetectable
5l66I-3csgA:
undetectable		 5l66H-3csgA:
20.95
5l66I-3csgA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 12 GLN A  49
ALA A 269
GLY A  54
THR A  53
ALA A  52
 None
 1.15A 5l66V-3csgA:
undetectable
5l66W-3csgA:
undetectable		 5l66V-3csgA:
20.95
5l66W-3csgA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		6 / 12 ALA A 342
ALA A 338
GLY A 166
ALA A 188
PHE A 169
VAL A 181
 None
 1.43A 5w4zA-3csgA:
undetectable		 5w4zA-3csgA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		6 / 12 ALA A 342
ALA A 338
GLY A 166
ALA A 188
PHE A 169
VAL A 181
 None
 1.45A 5w4zB-3csgA:
undetectable		 5w4zB-3csgA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		3 / 3 TYR A 155
ASN A 227
LEU A 113
 None
 0.79A 6b58A-3csgA:
undetectable		 6b58A-3csgA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		5 / 11 PRO A 133
GLU A 130
PRO A 254
ALA A 163
PRO A 159
 None
 1.46A 6bm5A-3csgA:
undetectable		 6bm5A-3csgA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3csg MALTOSE-BINDING
PROTEIN MONOBODY YS1
FUSION
(Escherichia
coli) 		4 / 7 ILE A 441
VAL A 380
ALA A 383
THR A 384
 None
 0.96A 6cduC-3csgA:
undetectable
6cduD-3csgA:
undetectable		 6cduC-3csgA:
21.29
6cduD-3csgA:
21.29