SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3csq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 VAL A 246
TRP A 225
TRP A 243
 None
 1.22A 2xdcC-3csqA:
undetectable
2xdcD-3csqA:
undetectable		 2xdcC-3csqA:
3.45
2xdcD-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 VAL A 246
TRP A 243
TRP A 225
 None
 1.30A 2xdcC-3csqA:
undetectable
2xdcD-3csqA:
undetectable		 2xdcC-3csqA:
3.45
2xdcD-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 TRP A 243
VAL A 246
TRP A 225
 None
 1.31A 2xdcC-3csqA:
undetectable
2xdcD-3csqA:
undetectable		 2xdcC-3csqA:
3.45
2xdcD-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 TRP A 243
VAL A 246
TRP A 225
 None
 1.29A 2xdcE-3csqA:
undetectable
2xdcF-3csqA:
undetectable		 2xdcE-3csqA:
3.45
2xdcF-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 TRP A 243
VAL A 246
TRP A 225
 None
 1.31A 2y5mE-3csqA:
undetectable
2y5mF-3csqA:
undetectable		 2y5mE-3csqA:
3.45
2y5mF-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 TRP A 243
VAL A 246
TRP A 225
 None
 1.31A 2y6nC-3csqA:
undetectable
2y6nD-3csqA:
undetectable		 2y6nC-3csqA:
3.45
2y6nD-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 TRP A 243
VAL A 246
TRP A 225
 None
 1.32A 2y6nE-3csqA:
undetectable
2y6nF-3csqA:
undetectable		 2y6nE-3csqA:
3.45
2y6nF-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 MET A  42
GLU A 100
ASN A 102
 None
 1.12A 3a27A-3csqA:
undetectable		 3a27A-3csqA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 8 TRP A 225
TRP A 279
PHE A 281
MET A 265
 None
 1.02A 3b3pA-3csqA:
undetectable
3b3pB-3csqA:
undetectable		 3b3pA-3csqA:
22.65
3b3pB-3csqA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_3
(PHOSPHOLIPASE A2)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 4 LYS A 287
ASN A 282
PHE A 281
TRP A 243
 None
 1.04A 3bjwF-3csqA:
0.0		 3bjwF-3csqA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 5 HIS A 278
HIS A 247
ASP A 195
HIS A 280
 None
None
ZN  A 335 (-2.1A)
ZN  A 335 (-3.1A)
 0.90A 3c0zA-3csqA:
undetectable		 3c0zA-3csqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 6 HIS A 278
HIS A 247
ASP A 195
HIS A 280
 None
None
ZN  A 335 (-2.1A)
ZN  A 335 (-3.1A)
 0.91A 3c0zC-3csqA:
undetectable		 3c0zC-3csqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 6 GLY A  51
TYR A  87
GLU A  93
GLY A  66
 None
 1.03A 3e9rA-3csqA:
undetectable		 3e9rA-3csqA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 6 GLY A  51
TYR A  87
GLU A  93
GLY A  66
 None
 1.01A 3e9rC-3csqA:
undetectable		 3e9rC-3csqA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 VAL A 246
TRP A 225
TRP A 243
 None
 1.19A 3zq8A-3csqA:
undetectable
3zq8B-3csqA:
undetectable		 3zq8A-3csqA:
3.45
3zq8B-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 VAL A 246
TRP A 243
TRP A 225
 None
 1.27A 3zq8A-3csqA:
undetectable
3zq8B-3csqA:
undetectable		 3zq8A-3csqA:
3.45
3zq8B-3csqA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 LEU A  22
MET A  42
LEU A  39
MET A  38
ILE A  98
 None
 1.13A 4j24B-3csqA:
undetectable		 4j24B-3csqA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 LEU A  22
MET A  42
LEU A  39
MET A  38
ILE A  98
 None
 1.17A 4j24C-3csqA:
undetectable		 4j24C-3csqA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 LEU A  22
MET A  42
LEU A  39
MET A  38
ILE A  98
 None
 1.17A 4j26B-3csqA:
undetectable		 4j26B-3csqA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 ASP A 195
TRP A 292
SER A 187
 ZN  A 335 (-2.1A)
None
ZN  A 335 ( 4.2A)
 1.03A 4lrhB-3csqA:
undetectable		 4lrhB-3csqA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 ASP A 195
TRP A 292
SER A 187
 ZN  A 335 (-2.1A)
None
ZN  A 335 ( 4.2A)
 1.01A 4lrhF-3csqA:
undetectable		 4lrhF-3csqA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 5 GLY A  40
ARG A 147
GLY A 148
GLU A 146
 None
 1.12A 4z2eB-3csqA:
undetectable
4z2eC-3csqA:
undetectable		 4z2eB-3csqA:
21.22
4z2eC-3csqA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 SER A 220
HIS A 278
HIS A 247
ASP A 195
HIS A 280
 None
None
None
ZN  A 335 (-2.1A)
ZN  A 335 (-3.1A)
 1.16A 5eeiA-3csqA:
undetectable		 5eeiA-3csqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 SER A 220
HIS A 278
HIS A 247
ASP A 195
HIS A 280
 None
None
None
ZN  A 335 (-2.1A)
ZN  A 335 (-3.1A)
 1.15A 5eeiB-3csqA:
undetectable		 5eeiB-3csqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 SER A 220
HIS A 278
HIS A 247
ASP A 195
HIS A 280
 None
None
None
ZN  A 335 (-2.1A)
ZN  A 335 (-3.1A)
 1.15A 5eenA-3csqA:
undetectable		 5eenA-3csqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 SER A 220
HIS A 278
HIS A 247
ASP A 195
HIS A 280
 None
None
None
ZN  A 335 (-2.1A)
ZN  A 335 (-3.1A)
 1.15A 5eenB-3csqA:
undetectable		 5eenB-3csqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 SER A 220
HIS A 278
HIS A 247
ASP A 195
HIS A 280
 None
None
None
ZN  A 335 (-2.1A)
ZN  A 335 (-3.1A)
 1.20A 5ef8A-3csqA:
undetectable		 5ef8A-3csqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 SER A 220
HIS A 278
HIS A 247
ASP A 195
HIS A 280
 None
None
None
ZN  A 335 (-2.1A)
ZN  A 335 (-3.1A)
 1.19A 5ef8B-3csqA:
undetectable		 5ef8B-3csqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 3csq MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 5 TYR A  87
LYS A  88
GLU A  58
GLY A  59
 None
 1.07A 5jhdJ-3csqA:
undetectable		 5jhdJ-3csqA:
22.19