SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3csy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3csy ENVELOPE
GLYCOPROTEIN GP2
(Zaire
ebolavirus) 		5 / 7 LEU J 515
TYR J 517
THR J 519
THR J 520
LEU J 558
 None
 0.40A 5jq7B-3csyJ:
9.5		 5jq7B-3csyJ:
99.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3csy ENVELOPE
GLYCOPROTEIN GP2
(Zaire
ebolavirus) 		5 / 10 LEU J 515
TYR J 517
THR J 519
MET J 548
LEU J 558
 None
 0.66A 6f5uA-3csyJ:
undetectable
6f5uB-3csyJ:
9.6		 6f5uA-3csyJ:
21.01
6f5uB-3csyJ:
98.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 3csy ENVELOPE
GLYCOPROTEIN GP2
(Zaire
ebolavirus) 		5 / 12 LEU J 515
TYR J 517
THR J 519
MET J 548
LEU J 558
 None
 0.32A 6f6iA-3csyJ:
undetectable
6f6iB-3csyJ:
9.6		 6f6iA-3csyJ:
21.01
6f6iB-3csyJ:
98.75