SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3csz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3csz MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 7 GLN A 106
PHE A 132
ASN A 104
GLU A 100
 NAG  A 202 (-3.3A)
None
None
None
 1.37A 1t9wA-3cszA:
undetectable		 1t9wA-3cszA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3csz MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		3 / 3 MET A  42
GLU A 100
ASN A 102
 None
 1.12A 3a27A-3cszA:
undetectable		 3a27A-3cszA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3csz MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 6 GLY A  51
TYR A  87
GLU A  93
GLY A  66
 None
 1.03A 3e9rA-3cszA:
undetectable		 3e9rA-3cszA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3csz MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 6 GLY A  51
TYR A  87
GLU A  93
GLY A  66
 None
 1.02A 3e9rC-3cszA:
undetectable		 3e9rC-3cszA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3csz MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 LEU A  22
MET A  42
LEU A  39
MET A  38
ILE A  98
 None
 1.16A 4j24B-3cszA:
undetectable		 4j24B-3cszA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 3csz MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 LEU A  22
MET A  42
LEU A  39
MET A  38
ILE A  98
 None
 1.20A 4j24C-3cszA:
undetectable		 4j24C-3cszA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3csz MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		5 / 12 LEU A  22
MET A  42
LEU A  39
MET A  38
ILE A  98
 None
 1.21A 4j26B-3cszA:
undetectable		 4j26B-3cszA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 3csz MORPHOGENESIS
PROTEIN 1
(Bacillus
virus
phi29) 		4 / 5 TYR A  87
LYS A  88
GLU A  58
GLY A  59
 None
 1.01A 5jhdJ-3cszA:
undetectable		 5jhdJ-3cszA:
19.92