SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ct7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		3 / 3 HIS A  63
MET A 135
MET A  65
 MG  A 232 (-3.3A)
MG  A 232 ( 4.9A)
MG  A 232 ( 4.8A)
 1.31A 2vj1A-3ct7A:
undetectable		 2vj1A-3ct7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		4 / 6 GLU A 171
MET A   1
PHE A 192
ILE A   3
 None
 1.25A 2w98B-3ct7A:
undetectable		 2w98B-3ct7A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		4 / 7 MET A 213
ILE A   3
HIS A  30
ILE A  22
 None
None
MG  A 232 (-3.5A)
None
 1.00A 3eteD-3ct7A:
undetectable
3eteF-3ct7A:
undetectable		 3eteD-3ct7A:
17.77
3eteF-3ct7A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC600_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		4 / 5 GLU A 101
HIS A 105
ARG A  78
ALA A  77
 None
 1.26A 3mbgB-3ct7A:
undetectable
3mbgC-3ct7A:
undetectable		 3mbgB-3ct7A:
19.48
3mbgC-3ct7A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		3 / 3 HIS A  63
HIS A  87
MET A  65
 MG  A 232 (-3.3A)
None
MG  A 232 ( 4.8A)
 0.67A 3mihA-3ct7A:
undetectable		 3mihA-3ct7A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		5 / 12 THR A  43
PHE A  48
VAL A 194
PHE A 200
HIS A  30
 None
None
None
None
MG  A 232 (-3.5A)
 1.38A 3u9fJ-3ct7A:
undetectable
3u9fK-3ct7A:
undetectable		 3u9fJ-3ct7A:
20.32
3u9fK-3ct7A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		4 / 5 ILE A  84
ALA A  77
MET A 107
ARG A 104
 None
 1.26A 4ac9B-3ct7A:
2.5
4ac9C-3ct7A:
2.6		 4ac9B-3ct7A:
16.77
4ac9C-3ct7A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		4 / 5 ILE A  84
ALA A  77
MET A 107
ARG A 104
 None
 1.26A 4acaB-3ct7A:
2.6
4acaC-3ct7A:
2.7		 4acaB-3ct7A:
16.77
4acaC-3ct7A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		4 / 5 LEU A 199
GLY A 195
ILE A  22
GLN A  18
 None
SO4  A 233 (-3.4A)
None
None
 1.21A 4ma8C-3ct7A:
undetectable		 4ma8C-3ct7A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3ct7 D-ALLULOSE-6-PHOSPHA
TE 3-EPIMERASE
(Escherichia
coli) 		5 / 12 LEU A 199
GLY A 195
CYH A 176
VAL A 172
ASP A 173
 None
SO4  A 233 (-3.4A)
None
None
MG  A 232 (-3.0A)
 1.32A 6bxlA-3ct7A:
undetectable		 6bxlA-3ct7A:
20.77