SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ctd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		3 / 3 LEU A 398
PRO A 399
LEU A 402
 None
 0.41A 1hrkA-3ctdA:
undetectable		 1hrkA-3ctdA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		3 / 3 LEU A 398
PRO A 399
LEU A 402
 None
 0.40A 3w1wB-3ctdA:
undetectable		 3w1wB-3ctdA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		4 / 5 LEU A 299
LEU A 344
ILE A 270
ARG A 271
 None
 1.03A 4klrA-3ctdA:
undetectable		 4klrA-3ctdA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		6 / 9 ASP A 311
VAL A 318
ALA A 340
TYR A 343
GLY A 308
SER A 347
 None
 1.44A 4mm5A-3ctdA:
undetectable		 4mm5A-3ctdA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		5 / 11 VAL A 318
ALA A 340
TYR A 343
GLY A 308
SER A 347
 None
 1.28A 4mm9A-3ctdA:
undetectable		 4mm9A-3ctdA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		6 / 9 ASP A 311
VAL A 318
ALA A 340
TYR A 343
GLY A 308
SER A 347
 None
 1.39A 4mmbA-3ctdA:
undetectable		 4mmbA-3ctdA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		6 / 12 ASP A 311
VAL A 318
ALA A 340
TYR A 343
GLY A 308
SER A 347
 None
 1.43A 4mmdB-3ctdA:
undetectable		 4mmdB-3ctdA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		6 / 9 ASP A 311
VAL A 318
ALA A 340
TYR A 343
GLY A 308
SER A 347
 None
 1.40A 4mmeA-3ctdA:
undetectable		 4mmeA-3ctdA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		6 / 9 ASP A 311
VAL A 318
ALA A 340
TYR A 343
GLY A 308
SER A 347
 None
 1.40A 4mmeB-3ctdA:
undetectable		 4mmeB-3ctdA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		6 / 9 ASP A 311
VAL A 318
ALA A 340
TYR A 343
GLY A 308
SER A 347
 None
 1.46A 4mmfA-3ctdA:
undetectable		 4mmfA-3ctdA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 3ctd PUTATIVE ATPASE, AAA
FAMILY
(Prochlorococcus
marinus) 		6 / 9 ASP A 311
VAL A 318
ALA A 340
TYR A 343
GLY A 308
SER A 347
 None
 1.45A 4mmfB-3ctdA:
1.4		 4mmfB-3ctdA:
17.99